Ohta, Shigeki

J-GLOBAL         Last updated: Nov 28, 2019 at 04:25
 
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Name
Ohta, Shigeki
E-mail
shiohtakeio.jp
URL
http://keiocancer.com/
Affiliation
Keio University
Section
School of Medicine Institute for Advanced Medical Research (Division of Cellular Signaling)
Job title
Senior Assistant Professor (Non-tenured)/Assistant Professor (Non-tenured)
Degree
Ph.D(Osaka University)
Research funding number
20365406

Research Areas

 
 

Education

 
Mar 1991
   
 
Faculty of Science, Osaka University
 
Mar 1997
   
 
Life Science, Graduate School, Division of Natural Science, Osaka University
 

Published Papers

 
Hirao N, Iwata T, Tanaka K, Nishio H, Nakamura M, Morisada T, Morii K, Maruyama N, Katoh Y, Yaguchi T, Ohta S, Kukimoto I, Aoki D, Kawakami Y
Gynecol Oncol   31478   Sep 2019   [Refereed]
Ohta, Shigeki, Kawakami, Yutaka, Okano, Hideyuki
ONCOTARGET   8(29) 46706-46707   Jul 2017
Saito, Katsuya, Ohta, Shigeki, Kawakami, Yutaka, Yoshida, Kazunari, Toda, Masahiro
JOURNAL OF NEURO-ONCOLOGY   132(1) 63-74   Mar 2017
Modeling of CHARGE syndrome using patient-derived iPSC reveals the defective migration of neural crest cells harboring CHD7 mutations.
Okuno H, Mihara FR, Ohta S, Fukuda K, Kurosawa K, Akamatsu W, Sanosaka1 T, Kohyama1 J, Ohyama M, Takahashi T, Swigut T, Wysocka J, Kosaki K, Okano H.
elife   6 e21114   2017   [Refereed]

Misc

 
シングルセル解析による抗腫瘍免疫応答の解明
大多茂樹、河上裕
医学のあゆみ   271(2)    Oct 2019   [Invited]
iPS細胞からの神経堤細胞誘導
大多茂樹、奥野博庸、岡野栄之
日本臨床社   115-120   Jun 2015   [Invited]
がん幹細胞を標的とした免疫療法
3. 河上裕、松下麻衣子、植田良、塚本信夫、大多茂樹
日本臨床   70(12) 2142-2146   Dec 2012
ヒトiPS細胞からのメラノサイトの作製
大多茂樹、河上裕.
医学のあゆみ   239(14) 1365-1370   Dec 2011

Books etc

 
Cell and Molecular Biology of Stem Cells and Imaging of Stem Cells
OHTA SHIGEKI (Part:Joint Work, Chapter 10: The Potential of Using Induced Pluripotent Stem Cells in Skin Diseases (pages 223–245))
Wiley   Aug 2014   ISBN:9781118284100
ヒトiPS細胞からのメラノサイトの作製
OHTA SHIGEKI (Part:Joint Work)
シーエムシー出版   Jul 2013   

Conference Activities & Talks

 
Peripheral blood CD8+T cell subsets correlated with PD-1 Ab response in melanoma patients by scRNA-seq analysis.
Ohta S, Matsumoto D, Nagumo H, Fujita T, Takahashi A, Namikawa K, Kitano A, Yamazaki N, Kawakami Y.
5th CRI-CIMT-EATI-AACR Interbational cancer immunotherapy conference.   26 Sep 2019   
Analysis of the regulatory mechanism underlying brain tumor-initiating cell proliferation by MIF.
Ohta S, Morimoto Y, Tokumitsu A, Sone T, Sakamoto A, Toda M, Kawakami Y, Okano H.
26 Jul 2019   
Functional analyses of TPT1 in neural stem/progenitor cells and glioma initiating cells.
OHTA SHIGEKI
The International Society for Neurochemistry   22 Aug 2017   
Macrophage migration inhibitory factor (MIF) supports the cell proliferation in brain tumor-initiating cells.
OHTA SHIGEKI
STEM CELLS & GENE THERAPY   Oct 2016   
MIFによるグリオーマ幹細胞増殖促進
OHTA SHIGEKI
第75回日本癌学会学術総会   Sep 2016   

Teaching Experience

 
 

Research Grants & Projects

 
子宮頸癌に対する腫瘍浸潤T細胞療法(TIL療法)実施にむけたTIL培養法の開発
Project Year: Apr 2019 - Today    Investigator(s): 岩田卓
MIFによる神経幹細胞制御機構の統合的理解
Project Year: Apr 2017 - Today    Investigator(s): 大多茂樹
がん免疫病態の個体差の解明とその制御による個別化がん治療の開発
Project Year: Apr 2014 - Mar 2019
Functional analyses of TCTP in neural stem/progenitor cells
MEXT,JSPS: Grant-in-Aid for Scientific Research
Project Year: Apr 2014 - Mar 2017    Investigator(s): 大多 茂樹
MIF (Macrophage migration inhibitory factor) was identified as a functional molecule, which supports the proliferation of murine neural stem/progenitor cells (NSPCs). We also identified a new factor TCTP1 (Tumor Protein Translationally-Controlled ...
CHDファミリーによる神経幹細胞およびグリオーマ幹細胞制御機構の解明
Project Year: Apr 2011 - Mar 2014

Patents

 
US 20040092448 A1 : Method of enhancing neural stem cell proliferation, differentiation, and survival using pituitary adenylate cyclase activating polypeptide (PACAP)