2021年9月
Cytologic features of Oral Squamous Cell Carcinoma in an Indo-Pacific Bottlenose Dolphin (Tursiops aduncus): Papanicolaou Stain and Immunocytochemistry Using Liquid-based Cytology
Veterinary Clinical Pathology
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- 巻
- 50
- 号
- 3
- 開始ページ
- 404
- 終了ページ
- 409
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1111/vcp.12996
Although oral cytology using Papanicolaou stain is useful for the early detection of oral premalignant lesions and squamous cell carcinoma (SCC) in people, little work has been conducted on this topic in veterinary medicine. This paper describes the features of oral cytology using Papanicolaou stain and immunocytochemistry on liquid-based cytology slides in a case of oral SCC in an Indo-Pacific bottlenose dolphin (Tursiops aduncus). In this case, dysplastic cells with koilocyte-like changes and SCC cells were identified using the Papanicolaou stain. These cells were positive for p53 using an immunocytochemistry analysis. A cytologic diagnosis of SCC was made. We believe that the early detection of premalignant oral lesions and SCC in dolphins can be significantly improved with cytology using liquid-based cytology, Papanicolaou staining, and immunocytochemistry.
- リンク情報
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- DOI
- https://doi.org/10.1111/vcp.12996
- PubMed
- https://www.ncbi.nlm.nih.gov/pubmed/34472131
- 共同研究・競争的資金等の研究課題
- 健康長寿をもたらす夏眠反応同定とその制御
- ID情報
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- DOI : 10.1111/vcp.12996
- PubMed ID : 34472131