論文

査読有り 国際誌
2019年5月

Medusozoan genomes inform the evolution of the jellyfish body plan.

Nature ecology & evolution
  • Konstantin Khalturin
  • ,
  • Chuya Shinzato
  • ,
  • Maria Khalturina
  • ,
  • Mayuko Hamada
  • ,
  • Manabu Fujie
  • ,
  • Ryo Koyanagi
  • ,
  • Miyuki Kanda
  • ,
  • Hiroki Goto
  • ,
  • Friederike Anton-Erxleben
  • ,
  • Masaya Toyokawa
  • ,
  • Sho Toshino
  • ,
  • Noriyuki Satoh

3
5
開始ページ
811
終了ページ
822
記述言語
英語
掲載種別
DOI
10.1038/s41559-019-0853-y

Cnidarians are astonishingly diverse in body form and lifestyle, including the presence of a jellyfish stage in medusozoans and its absence in anthozoans. Here, we sequence the genomes of Aurelia aurita (a scyphozoan) and Morbakka virulenta (a cubozoan) to understand the molecular mechanisms responsible for the origin of the jellyfish body plan. We show that the magnitude of genetic differences between the two jellyfish types is equivalent, on average, to the level of genetic differences between humans and sea urchins in the bilaterian lineage. About one-third of Aurelia genes with jellyfish-specific expression have no matches in the genomes of the coral and sea anemone, indicating that the polyp-to-jellyfish transition requires a combination of conserved and novel, medusozoa-specific genes. While no genomic region is specifically associated with the ability to produce a jellyfish stage, the arrangement of genes involved in the development of a nematocyte-a phylum-specific cell type-is highly structured and conserved in cnidarian genomes; thus, it represents a phylotypic gene cluster.

リンク情報
DOI
https://doi.org/10.1038/s41559-019-0853-y
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/30988488