Yasuyuki Fujita

Profile Information

Affiliation: Chief, Dermatology, Sapporo City General Hospital
: Hokkaido University

Degree: 医学博士(北海道大学)

J-GLOBAL ID: 200901029514151292
researchmap Member ID: 5000090051

External link: http://www.derm-hokudai.jp/

Research Interests

Research Areas

Life sciences / Dermatology /

Research History

Apr, 2019 - Present

Dermatology, Sapporo City General Hospital
Oct, 2015 - Mar, 2019

Associate Professor, Dermatology, Hokkaido University Hospital
Jan, 2011 - Sep, 2015

Assistant Professor, Dermatology, Hokkaido University Hospital

Education

Apr, 2006 - Dec, 2010

Graduate School of Medicine, Hokkaido University
Apr, 1996 - Mar, 2002

Hokkaido University

Awards

Major Papers

175

Rash after consumption of game meat

Yuka Maya, Yasuyuki Fujita, Fumihiro Kodama, Satoko Shimizu

BMJ, n508-n508, Mar 10, 2021 Peer-reviewedCorresponding author
Intravenous allogeneic multilineage-differentiating stress-enduring cells in adults with dystrophic epidermolysis bullosa: a phase 1/2 open-label study.

Y Fujita, T Nohara, S Takashima, K Natsuga, M Adachi, K Yoshida, S Shinkuma, T Takeichi, H Nakamura, O Wada …

Journal of the European Academy of Dermatology and Venereology : JEADV, Mar 3, 2021 Peer-reviewedLead authorCorresponding author
Intravenous Injection of Muse Cells as a Potential Therapeutic Approach for Epidermolysis Bullosa.

Yasuyuki Fujita, Miho Komatsu, San Eun Lee, Yoshihiro Kushida, Chihiro Nakayama-Nishimura, Wakana Matsumura, Shota Takashima, Satoru Shinkuma, Toshifumi Nomura, Naoya Masutomi …

The Journal of investigative dermatology, 141(1) 198-202, Jan, 2021 Peer-reviewedLead authorCorresponding author
Cultured Epidermal Autografts from Clinically Revertant Skin as a Potential Wound Treatment for Recessive Dystrophic Epidermolysis Bullosa.

Matsumura W, Fujita Y, Shinkuma S, Suzuki S, Yokoshiki S, Goto H, Hayashi H, Ono K, Inoie M, Takashima S …

The Journal of investigative dermatology, 139(10) 2115-2124, Oct, 2019 Peer-reviewedLead authorCorresponding author
The development of induced pluripotent stem cell-derived mesenchymal stem/stromal cells from normal human and RDEB epidermal keratinocytes.

Chihiro Nakayama, Yasuyuki Fujita, Wakana Matsumura, Inkin Ujiie, Shota Takashima, Satoru Shinkuma, Toshifumi Nomura, Riichiro Abe, Hiroshi Shimizu

Journal of dermatological science, 91(3) 301-310, Sep, 2018 Peer-reviewedCorresponding author
Establishment of integration-free induced pluripotent stem cells from human recessive dystrophic epidermolysis bullosa keratinocytes.

Wakana Matsumura, Yasuyuki Fujita, Chihiro Nakayama, Satoru Shinkuma, Shotaro Suzuki, Toshifumi Nomura, Riichiro Abe, Hiroshi Shimizu

Journal of dermatological science, 89(3) 263-271, Mar, 2018 Peer-reviewedCorresponding author
Eosinophilic annular erythema is clinically characterized by central pigmentation reflecting basal melanosis: a clinicopathological study of 10 cases

S. Nakazato, Y. Fujita, S. Shinkuma, T. Nomura, H. Shimizu

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, 31(11) 1916-1923, Nov, 2017 Peer-reviewedCorresponding author
Renal failure in dogs kept by a man with severe psoriasis

Y. Fujita, K. Hanazono, E. Uchida, T. Kawahata, A. Suto, K. Nakamura, H. Shimizu

Journal of the European Academy of Dermatology and Venereology, 31(4) e184-e185, Apr 1, 2017 Peer-reviewedLead authorCorresponding author
Altered balance of epidermis-related chemokines in epidermolysis bullosa

Inkin Ujiie, Yasuyuki Fujita, Chihiro Nakayama, Wakana Matsumura, Shotaro Suzuki, Satoru Shinkuma, Toshifumi Nomura, Riichiro Abe, Hiroshi Shimizu

JOURNAL OF DERMATOLOGICAL SCIENCE, 86(1) 37-45, Apr, 2017 Peer-reviewedCorresponding author
Intravascular large B-cell lymphoma疑診例に対して施行したランダム皮膚生検33名の検討

辻脇真澄, 藤田靖幸, 清水宏

日本皮膚科学会雑誌, 124(7) 1305-1311, Jun, 2014 Peer-reviewedCorresponding author
Infantile eczema caused by formula milk.

Takamasa Ito, Wataru Nishie, Yasuyuki Fujita, Riichiro Abe, Hiroshi Shimizu

Lancet (London, England), 381(9881) 1958-1958, Jun 1, 2013 Peer-reviewed
Bone marrow transplantation restores epidermal basement membrane protein expression and rescues epidermolysis bullosa model mice

Yasuyuki Fujita, Riichiro Abe, Daisuke Inokuma, Mikako Sasaki, Daichi Hoshina, Ken Natsuga, Wataru Nishie, James R. McMillan, Hideki Nakamura, Tadamichi Shimizu …

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 107(32) 14345-14350, Aug, 2010 Peer-reviewedLead author
Mesenchymal stem cells are recruited into wounded skin and contribute to wound repair by transdifferentiation into multiple skin cell type

Mikako Sasaki, Riichiro Abe, Yasuyuki Fujita, Satomi Ando, Daisuke Inokuma, Hiroshi Shimizu

JOURNAL OF IMMUNOLOGY, 180(4) 2581-2587, Feb, 2008 Peer-reviewed
Presence of circulating CCR10+T cells and elevated serum CTACK/CCL27 in the early stage of mycosis fungoides

Y Fujita, R Abe, M Sasaki, A Honda, M Furuichi, Y Asano, O Norisugi, T Shimizu, H Shimizu

CLINICAL CANCER RESEARCH, 12(9) 2670-2675, May, 2006 Peer-reviewedLead author

Misc.

経過中ぶどう膜炎を併発した尋常性乾癬の小児の1例

宮澤元, 藤田靖幸, 村松憲, 岩田浩明, 南場研一, 保科大地, 清水宏

日本皮膚科学会雑誌, 128(4) 608-608, Apr, 2018
小児線状強皮症に対してシクロスポリン内服が有効であった3例

眞井翔子, 藤田靖幸, 宮内俊成, 藤村悠, 夏賀健, 乃村俊史, 西江渉, 清水宏, 小野寺智洋, 岡敏明

日本皮膚科学会雑誌, 128(1) 62-62, Jan, 2018
膿疱性乾癬とMikulicz病が合併した1例

宮澤元, 藤田靖幸, 岩田浩明, 清水宏, 石川康暢, 西尾妙織, 石嶋漢, 新明康弘

日本皮膚科学会雑誌, 127(9) 2122-2122, Aug, 2017
Matrix-assisted laser desorption ionization time-of-flight mass spectrometry(MALDI-TOF/MS)が診断に有用であったMicrosporum canis感染症の家族例

山口泰之, 藤田靖幸, 白戸貴久, 新熊悟, 夏賀健, 乃村俊史, 清水宏, 福元達也

日本皮膚科学会雑誌, 127(9) 2115-2115, Aug, 2017
Thymoma-associated multiorgan autoimmunity(TAMA)の2例

得地景子, 藤田靖幸, 宮澤元, 村松憲, 渡邉美佳, 西村真智子, 新熊悟, 乃村俊史, 西江渉, 清水宏 …

日本皮膚科学会雑誌, 127(9) 2118-2118, Aug, 2017
真皮全層で増生する毛細血管

藤田靖幸, 新熊悟, 清水宏

日本皮膚悪性腫瘍学会学術大会プログラム・抄録集, 33回 108-108, May, 2017
ENPP1に新規ミスセンス変異を同定したCole病の1家系

宮内俊成, 乃村俊史, 鈴木翔多朗, 竹田真依, 新熊悟, 氏家英之, 藤田靖幸, 阿部理一郎, 清水宏

日本皮膚科学会雑誌, 127(5) 1170-1170, May, 2017
新規ケラチン1遺伝子変異によるichthyosis with confettiの1家系

鈴木翔多朗, 乃村俊史, 宮内俊成, 竹田真依, 中村秀樹, 新熊悟, 藤田靖幸, 清水宏, 秋山真志

角化症研究会記録集, 31 12-17, Mar, 2017
色素異常を伴う掌蹠角化症の1家系

宮内俊成, 乃村俊史, 鈴木翔多朗, 竹田真依, 新熊悟, 氏家英之, 藤田靖幸, 清水宏, 阿部理一郎

角化症研究会記録集, 31 114-117, Mar, 2017
タクロリムス軟膏で完全消退が得られたangiolymphoid hyperplasia with eosinophiliaの1例

原田晋平, 乃村俊史, 宮内俊成, 新熊悟, 藤田靖幸, 清水宏, 有田賢

日本皮膚科学会雑誌, 127(2) 193-193, Feb, 2017
重症汎発型単純型表皮水疱症の家族例

須貝達朗, 新熊悟, 高島翔太, 乃村俊史, 藤田靖幸, 中村秀樹, 清水宏, 稲福和宏

日本皮膚科学会雑誌, 127(2) 221-221, Feb, 2017
広範囲に皮疹を生じた長島型掌蹠角化症の1例

宮内俊成, 乃村俊史, 鈴木翔多朗, 大口由香, 山口泰之, 新熊悟, 夏賀健, 藤田靖幸, 清水宏

日本皮膚科学会雑誌, 126(9) 1725-1725, Aug, 2016
タクロリムス軟膏が著効したangiolymphoid hyperplasia with eosinophiliaの1例

原田晋平, 乃村俊史, 宮内俊成, 新熊悟, 藤田靖幸, 清水宏, 有田賢

日本皮膚科学会雑誌, 126(9) 1726-1726, Aug, 2016
病理学的に乾癬様の変化を呈した菌状息肉症の2例

山口泰之, 藤田靖幸, 平田悠, 西村真智子, 夏賀健, 清水宏, 肥田時征, 加藤直子

日本皮膚科学会雑誌, 126(7) 1331-1331, Jun, 2016
前額部に限局してmulticentric Castleman diseaseの皮膚病変を認めた1例

佐藤一正, 新熊悟, 秋野愛, 乃村俊史, 藤田靖幸, 阿部理一郎, 清水宏

日本皮膚科学会雑誌, 126(7) 1331-1331, Jun, 2016
Eosinophilic annular erythema 10例の臨床病理学的検討

中里信一, 藤田靖幸, 新熊悟, 乃村俊史, 清水宏

日本皮膚病理組織学会抄録集, 32回 42-42, Jun, 2016
広範囲に皮疹を生じた長島型掌蹠角化症の1例

宮内俊成, 乃村俊史, 鈴木翔多朗, 大口由香, 山口泰之, 新熊悟, 夏賀健, 藤田靖幸, 清水宏

日本皮膚科学会雑誌, 126(5) 979-979, May, 2016
Eosinophilic annular erythema 10例の臨床病理学的検討

中里信一, 藤田靖幸, 新熊悟, 乃村俊史, 清水宏

日本皮膚科学会雑誌, 126(6) 1123-1123, May, 2016
長島型掌蹠角化症の1例

宮内俊成, 乃村俊史, 鈴木翔多朗, 山口泰之, 夏賀健, 藤田靖幸, 清水宏

角化症研究会記録集, 30 78-82, Mar, 2016
病理学的に乾癬様の変化を呈した菌状息肉症の2例

山口泰之, 藤田靖幸, 平田悠, 西村真智子, 夏賀健, 清水宏, 肥田時征, 加藤直子

日本皮膚科学会雑誌, 126(2) 167-167, Feb, 2016

Presentations

Epitope spreading現象によって抗BP180 NC16a抗体が陽転化したdipeptidyl peptidase-IV阻害薬関連水疱性類天疱瘡の3例

眞井洋輔, 西江渉, 泉健太郎, 葭本倫大, 森田裕介, 渡邉美佳, 豊永愛恋, 氏家英之, 岩田浩明, 藤田靖幸, 乃村俊史, 松村和子, 清水聡子, 清水宏

加齢皮膚医学セミナー, Jun, 2019, 加齢皮膚医学研究会
抗デスモグレイン3抗体がCLEIAで陰性、ELISAで陽性となった尋常性天疱瘡の1例

眞井洋輔, 氏家英之, 西村真智子, 古賀浩嗣, 真屋由佳, 得地景子, 藤田靖幸, 三河洋平, 清水宏

西日本皮膚科, Jun, 2018, 日本皮膚科学会-西部支部
経過中ぶどう膜炎を併発した尋常性乾癬の小児の1例

宮澤元, 藤田靖幸, 村松憲, 岩田浩明, 南場研一, 保科大地, 清水宏

日本皮膚科学会雑誌, Apr, 2018, (公社)日本皮膚科学会
小児線状強皮症に対してシクロスポリン内服が有効であった3例

眞井翔子, 藤田靖幸, 宮内俊成, 藤村悠, 夏賀健, 乃村俊史, 西江渉, 清水宏, 小野寺智洋, 岡敏明

日本皮膚科学会雑誌, Jan, 2018, (公社)日本皮膚科学会
Two families of nail-patella syndrome with novel splice site mutations in the LMX1B gene

S. Shinkuma, H. Nakamura, S. Takashima, T. Nomura, Y. Fujita, S. Hasegawa, K. Matsumura, H. Shimizu, R. Abe

JOURNAL OF INVESTIGATIVE DERMATOLOGY, Oct, 2017, ELSEVIER SCIENCE INC
Chromosomal inversions as a hidden disease-modifying factor

T. Nomura, S. Suzuki, T. Miyauchi, M. Takeda, Y. Fujita, W. Nishie, M. Akiyama, H. Shimizu

JOURNAL OF INVESTIGATIVE DERMATOLOGY, Oct, 2017, ELSEVIER SCIENCE INC
CL2020, a human multilineage-differentiating stress enduring cells-rich product, has a potential to treat dystrophic epidermolysis bullosa

Y. Fujita, S. Shinkuma, S. Lee, C. Nakayama, W. Matsumura, T. Nomura, M. Kawamura, N. Masutomi, H. Shimizu

JOURNAL OF INVESTIGATIVE DERMATOLOGY, Oct, 2017, ELSEVIER SCIENCE INC
膿疱性乾癬とMikulicz病が合併した1例

宮澤元, 藤田靖幸, 岩田浩明, 清水宏, 石川康暢, 西尾妙織, 石嶋漢, 新明康弘

日本皮膚科学会雑誌, Aug, 2017
Myxoinflammatory fibroblastic sarcomaの1例

前田拓哉, 藤田靖幸, 秦洋郎, 今福恵輔, 中里信一, 清水宏, 三橋智子, 長谷川匡, 阿南隆, 浜岡秀爾

日本皮膚科学会雑誌, Aug, 2017
腹部に生じたapocrine mixed tumorの1例

眞井翔子, 藤田靖幸, 須貝達朗, 今福恵輔, 秦洋郎, 新熊悟, 乃村俊史, 清水宏

日本皮膚科学会雑誌, Aug, 2017
Thymoma-associated multiorgan autoimmunity(TAMA)の2例

得地景子, 藤田靖幸, 宮澤元, 村松憲, 渡邉美佳, 西村真智子, 新熊悟, 乃村俊史, 西江渉, 清水宏, 田口純, 木下一郎

日本皮膚科学会雑誌, Aug, 2017
アダリムマブ投与中に皮下血腫を生じた乾癬性関節炎の1例

真屋由佳, 藤田靖幸, 中山ちひろ, 北村真也, 秦洋郎, 清水宏, 有田賢

日本皮膚科学会雑誌, Aug, 2017
Matrix-assisted laser desorption ionization time-of-flight mass spectrometry(MALDI-TOF/MS)が診断に有用であったMicrosporum canis感染症の家族例

山口泰之, 藤田靖幸, 白戸貴久, 新熊悟, 夏賀健, 乃村俊史, 清水宏, 福元達也

日本皮膚科学会雑誌, Aug, 2017
Juvenile spring eruptionの1例

白戸貴久, 西村真智子, 新熊悟, 氏家英之, 乃村俊史, 藤田靖幸, 清水宏, 阿部理一郎

日本皮膚科学会雑誌, Aug, 2017
アダリムマブが著効したアロポー稽留性肢端皮膚炎の1例

佐藤一正, 藤田靖幸, 葭本倫大, 椎谷千尋, 安藤佐土美, 清水宏

皮膚科の臨床, Jul, 2017
ENPP1に新規ミスセンス変異を同定したCole病の1家系

宮内俊成, 乃村俊史, 鈴木翔多朗, 竹田真依, 新熊悟, 氏家英之, 藤田靖幸, 阿部理一郎, 清水宏

日本皮膚科学会雑誌, May, 2017, (公社)日本皮膚科学会
真皮全層で増生する毛細血管

藤田靖幸, 新熊悟, 清水宏

日本皮膚悪性腫瘍学会学術大会プログラム・抄録集, May, 2017, (一社)日本皮膚悪性腫瘍学会
Gene-edition targeting mutation site recovers null-expression of type VII collagen caused by frameshift mutation via non-homologous end joining in Recessive Dystrophic Epidermolysis Bullosa

S. Takashima, S. Shinkukma, Y. Fujita, T. Nomura, H. Ujiie, R. Abe, H. Shimizu

JOURNAL OF INVESTIGATIVE DERMATOLOGY, May, 2017, ELSEVIER SCIENCE INC
A case of recessive dystrophic epidermolysis bullosa with a novel c.6885_6898del14 mutation

S. Shinkukma, T. Masunaga, S. Miyawaki, S. Takashima, T. Nomura, Y. Fujita, H. Nakamura, H. Shimizu

JOURNAL OF INVESTIGATIVE DERMATOLOGY, May, 2017, ELSEVIER SCIENCE INC
色素異常を伴う掌蹠角化症の1家系

宮内俊成, 乃村俊史, 鈴木翔多朗, 竹田真依, 新熊悟, 氏家英之, 藤田靖幸, 清水宏, 阿部理一郎

角化症研究会記録集, Mar, 2017

Research Projects

Establishment of epidermolysis bullosa model mouse with revertant mosaicism and its treatment

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (A), Grant-in-Aid for Scientific Research (A), Japan Society for the Promotion of Science, Apr, 2017 - Mar, 2020

Shimizu Hiroshi
Comprehensive study for pathogenesis of severe drug eruption

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B), Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2015 - Mar, 2018

Abe Riichiro
Treatment of epidermolysis bullosa with revertant keratinocyte-derived iPS cells

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2015 - Mar, 2018

Fujita Yasuyuki, MATSUMURA WAKANA, NAKAYAMA CHIHIRO
復帰変異モザイク（Revertant mosaicism）を応用した先天性難治性皮膚疾患に対する自家培養表皮シート療法

希少疾病用再生医療品等開発支援事業, 医薬基盤・健康・栄養研究所, Dec, 2014 - Mar, 2018

清水宏, 西江渉, 藤田靖幸, 新熊悟, 井家益和, 佐藤典宏
Investigation of induced stem cells treatment for epidermolysis bullosa

Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (A), Grant-in-Aid for Young Scientists (A), Japan Society for the Promotion of Science, Apr, 2013 - Mar, 2015

FUJITA Yasuyuki
Investigation of hematopoietic stem cell transplantation for epidermolysis bullosa

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (A), Grant-in-Aid for Scientific Research (A), Japan Society for the Promotion of Science, Apr, 2012 - Mar, 2015

SHIMIZU Hiroshi, ABE Riichiro, NISHIE Wataru, FUJITA Yasuyuki, AKIYAMA Masashi, KOJIMA Seiji, NAKAMURA Hideki
Investigation for pathogenesis of cutaneous severe adverse drug reaction.

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B), Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2012 - Mar, 2015

ABE Riichiro, FUJITA Yasuyuki
Contribution of mitochondrioa to keratinization

Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Exploratory Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, Apr, 2013 - Mar, 2014

ABE Riichiro, FUJITA Yasuyuki, SUTO Asuka
Development of cell therapy for epidermolysis bullosa

Grants-in-Aid for Scientific Research, Grant-in-Aid for Young Scientists (A), Japan Society for the Promotion of Science, 2011 - 2012

FUJITA Yasuyuki
Development of stem cell therapy for epidermolysis bullosa model mice expressing humanized dermo-epidermal junctional protein

Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Exploratory Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, 2011 - 2011

SHIMIZU Hiroshi, ABE Riichiro, FUJITA Yasuyuki
骨髄由来細胞を用いた皮膚構成細胞分化の研究

その他の研究制度, 2006

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