2018年12月19日
Ishigadine A, a new canthin-6-one alkaloid from an Okinawan marine sponge Hyrtios sp.
Tetrahedron Letters
- ,
- ,
- ,
- 巻
- 59
- 号
- 51
- 開始ページ
- 4500
- 終了ページ
- 4502
- 記述言語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1016/j.tetlet.2018.11.019
- 出版者・発行元
- Elsevier {BV}
A new indole alkaloid with the canthin-6-one skeleton, ishigadine A, has been isolated from an Okinawan marine sponge Hyrtios sp. The structure of ishigadine A was elucidated on the basis of spectroscopic analyses. Ishigadine A is a new canthin-6-one alkaloid possessing a hydroxy group, a 1,3-dimethyl-4-methylthioimidazolium, and a 1-propylguanidine. Ishigadine A is the third canthin-6-one alkaloid from sponges. Ishigadine A might be generated from L-arginine, L-histidine, and L-tryptophan. Ishigadine A exhibited moderate cytotoxicity against L1210 murine leukemia cells.
- リンク情報
- ID情報
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- DOI : 10.1016/j.tetlet.2018.11.019
- ISSN : 0040-4039
- eISSN : 1873-3581
- ORCIDのPut Code : 50400573
- SCOPUS ID : 85056655611