KURISU SHUSAKU

Profile Information

Affiliation: Assistant Professor, Kobe University
: 研究員, 和光研究所脳科学総合研究センター発生遺伝子制御研究チーム, 独立行政法人理化学研究所
: 特命助教, 神戸大学大学院医学研究科

Degree: 博士（薬学）(東京大学)

J-GLOBAL ID: 200901012281416444
researchmap Member ID: 5000090664

External link: http://pub2.db.tokushima-u.ac.jp/ERD/person/312435/profile-ja.html

Research Interests

Research Areas

Research History

May, 2016 - Present

The University of Tokushima
- Mar, 2016

Graduate School of Medicine, Kobe University
- Feb, 2009

研究員, 脳科学総合研究センター, 理化学研究所
- Mar, 2007

The University of Tokyo Graduate School of Pharmaceutical Sciences

Education

Apr, 2002 - Mar, 2007

機能薬学専攻, 薬学系研究科, 東京大学大学院
Apr, 2000 - Mar, 2002

Department of Chemistry and Biotechnology, The Faculty of Engineering, The University of Tokyo

Papers

Proximal deposition of collagen IV by fibroblasts contributes to basement membrane formation by colon epithelial cells in vitro.

Aya Tentaku, Shusaku Kurisu, Kurumi Sejima, Toshiki Nagao, Akira Takahashi, Shigenobu Yonemura

The FEBS journal, Jun 22, 2022 Peer-reviewedCorresponding author
JRAB/MICAL-L2 undergoes liquid-liquid phase separation to form tubular recycling endosomes.

Ayuko Sakane, Taka-Aki Yano, Takayuki Uchihashi, Kazuki Horikawa, Yusuke Hara, Issei Imoto, Shusaku Kurisu, Hiroshi Yamada, Kohji Takei, Takuya Sasaki

Communications biology, 4(1) 551-551, May 11, 2021 Peer-reviewed
Basement membrane dynamics in epithelial morphogenesis

Kurisu Shusaku, Yonemura Shigenobu

Shikoku acta medica, 77(1) 17-24, Apr 25, 2021 Peer-reviewedLead author
Pkd2l1 is required for mechanoception in cerebrospinal fluid-contacting neurons and maintenance of spine curvature.

Sternberg JR, Prendergast AE, Brosse L, Cantaut-Belarif Y, Thouvenin O, Orts-Del'Immagine A, Castillo L, Djenoune L, Kurisu S, McDearmid JR …

Nature communications, 9(1) 3804, Sep, 2018 Peer-reviewed
alpha-Actinin-4 Enhances Colorectal Cancer Cell Invasion by Suppressing Focal Adhesion Maturation

Miki Fukumoto, Shusaku Kurisu, Tesshi Yamada, Tadaomi Takenawa

PLOS ONE, 10(4) e0120616, Apr, 2015 Peer-reviewedLead author
DYNAMIC SHAPING OF CELLULAR MEMBRANES BY PHOSPHOLIPIDS AND MEMBRANE-DEFORMING PROTEINS

Shiro Suetsugu, Shusaku Kurisu, Tadaomi Takenawa

PHYSIOLOGICAL REVIEWS, 94(4) 1219-1248, Oct, 2014 Peer-reviewed
Antagonistic regulation of F-BAR protein assemblies controls actin polymerization during podosome formation

Kazuya Tsujita, Akihiro Kondo, Shusaku Kurisu, Junya Hasegawa, Toshiki Itoh, Tadaomi Takenawa

JOURNAL OF CELL SCIENCE, 126(10) 2267-2278, May, 2013 Peer-reviewed
WASP and WAVE family proteins: friends or foes in cancer invasion?

Kurisu Shusaku

Cancer Sci, 101(10) 2093-104, Oct, 2010 Peer-reviewedLead author
Involvement of Rac and Rho signaling in cancer cell motility in 3D substrates

D. Yamazaki, S. Kurisu, T. Takenawa

ONCOGENE, 28(13) 1570-1583, Apr, 2009 Peer-reviewedLead author
The WASP and WAVE family proteins.

Kurisu S, Takenawa T

Genome biology, 10(6) 226, 2009 Peer-reviewedLead author
Optimization of WAVE2 complex-induced actin polymerization by membrane-bound IRSp53, PIP3, and Rac

S Suetsugu, S Kurisu, T Oikawa, D Yamazaki, A Oda, T Takenawa

JOURNAL OF CELL BIOLOGY, 173(4) 571-585, May, 2006 Peer-reviewed
Regulation of cancer cell motility through actin reorganization

D Yamazaki, S Kurisu, T Takenawa

CANCER SCIENCE, 96(7) 379-386, Jul, 2005 Peer-reviewed
Rac-WAVE2 signaling is involved in the invasive and metastatic phenotypes of murine melanoma cells

S Kurisu, S Suetsugu, D Yamazaki, H Yamaguchi, T Takenawa

ONCOGENE, 24(8) 1309-1319, Feb, 2005 Peer-reviewedLead author
N-WASP and WAVE2 acting downstream of phosphatidylinositol 3-kinase are required for myogenic cell migration induced by hepatocyte growth factor

K Kawamura, K Takano, S Suetsugu, S Kurisu, D Yamazaki, H Miki, T Takenawa, T Endo

JOURNAL OF BIOLOGICAL CHEMISTRY, 279(52) 54862-54871, Dec, 2004 Peer-reviewed
Differential roles of WAVE1 and WAVE2 in dorsal and peripheral ruffle formation for fibroblast cell migration

S Suetsugu, D Yamazaki, S Kurisu, T Takenawa

DEVELOPMENTAL CELL, 5(4) 595-609, Oct, 2003 Peer-reviewed

Misc.

上皮基底膜IV型コラーゲンの動態解析

天宅あや, 栗栖修作, 高橋章, 米村重信

日本生化学会大会プログラム・講演要旨集, 94回 [P-388], Nov, 2021
間質細胞由来IV型コラーゲンががん細胞に与える影響

天宅あや, 栗栖修作, 米村重信, 高橋章

四国医学雑誌, 77(1-2) 108-109, Apr, 2021
Microvillar tip-localized interaction between IRSp53 and PI(4,5)P2 drives brush border assembly in kidney epithelial cells.

S. Kurisu, T. Itoh, T. Takenawa

MOLECULAR BIOLOGY OF THE CELL, 25, Dec, 2014
α-アクチニン4は接着斑の成熟を抑制することにより細胞の浸潤を亢進する

福本未記, 栗栖修作, 竹縄忠臣

日本生化学会大会プログラム・講演要旨集, 87回 [2P-245], Oct, 2014
組織工学的層状上皮細胞における上皮間葉移行(Transitions between epithelial and mesenchymal states in tissue-engineered stratified epithelial cell sheets)

村上大輔, 大和雅之, 栗栖修作, 高木亮, 近藤誠, 杉山洋章, 大木岳志, 岡野光夫, 竹縄忠臣

日本細胞生物学会大会講演要旨集, 63回 143-143, May, 2011
N‐WASP/WAVEのシグナルと癌浸潤,転移

竹縄忠臣, 末次志郎, 山崎大輔, 及川司, 栗栖修作

日本癌学会学術総会記事, 65th 433, Aug 28, 2006
Differential roles of WAVE1 and WAVE2 in dorsal and peripheral ruffle formation for fibroblast cell migration in the presence or absence of extracellular matrix

Shiro Suetsugu, Daisuke Yamazaki, Shusaku Kurisu, Tadaomi Takenawa

CELL STRUCTURE AND FUNCTION, 29 24-24, May, 2004
N-WASP and WAVE2 are required for myogenic cell migration induced by hepatocyte growth factor

Kazuhiro Kawamura, Shiro Suetsugu, Shusaku Kurisu, Tadaomi Takenawa, Takeshi Endo

CELL STRUCTURE AND FUNCTION, 29 24-24, May, 2004
WAVE2 is involved in the invasive and metastatic phenotypes of murine melanoma cells

Shusaku Kurisu, Shiro Suetsugu, Daisuke Yamazaki, Hideki Yamaguchi, Tadaomi Takenawa

CELL STRUCTURE AND FUNCTION, 29 24-24, May, 2004

Books and Other Publications

UCSD Molecular Pages “WAVE2”

Tadaomi Takenawa, Shiro Suetsugu, Daisuke Yamazaki, Shusaku Kurisu (Role: Joint author)

UCSD Signaling Gateway, Sep, 2012
改訂タンパク質実験ハンドブック，第9章・第11章

Shusaku Kurisu

YODOSHA CO., LTD., Jan 14, 2011
細胞遊走研究のパラダイムシフト~二次元から三次元へ (第4章2)

Shusaku Kurisu

YODOSHA CO., LTD., Aug 4, 2006
がん細胞の生物学：がん研究のいま2「3-7 細胞運動と細胞がん化」

竹縄忠臣, 栗栖修作 (Role: Joint author)

東京大学出版会, Feb, 2006 (ISBN: 4130642421)
タンパク質実験ハンドブック, 第８章ー２

栗栖修作 (Role: Joint author)

羊土社, Aug, 2003

Presentations

Proximal deposition of collagen IV by fibroblasts contributes to basement membrane formation by colon epithelial cells in vitro

Shusaku Kurisu, Aya Tentaku, Shigenobu Yonemura

Jun 28, 2022
Quantitative changes of actin-binding proteins in mechanosensing at the epithelial cell-cell junction

Shusaku Kurisu, Shigenobu Yonemura

The 73rd Annual Meeting of the Japan Society for Cell Biology, Jul 1, 2021
The roles of cortical actin rings in the establishment of epithelial cell polarity

Shusaku Kurisu, Shigenobu Yonemura

The 126th Annual Meeting of The Japanese Association of Anatomists, The 98th Annual Meeting of The Physiological Society of Japan,, Mar 30, 2021
Formation and maintenance of the epithelial basement membrane

Shusaku Kurisu, Shigenobu Yonemura

Mar 7, 2021 Invited
Protein quantification at epithelial cell-cell junctions reveals a differential distribution of the actin-associated components

Shusaku Kurisu, Shigenobu Yonemura

The 72nd Annual Meeting of the Japan Society for Cell Biology, Jun 10, 2020
The epithelial apico-basal boundary is defined by a cortical actomyosin ring

Shusaku Kurisu, Shigenobu Yonemura

Joint Annual Meeting of 71st JSCB & 19 th PAAJ, Jun 24, 2019
蛍光タンパク質ノックインによる細胞間接着タンパク質の定量

Shusaku Kurisu, Shigenobu Yonemura

第4回日本メカノバイオロジー学会学術総会, Mar 15, 2019
Determination of protein composition at epithelial cell-cell junctions by CRISPR/Cas9-mediated fluorescent protein knockin

Shusaku Kurisu, Shigenobu Yonemura

Joint Annual Meeting of 70th JSCB and 51st JSDB co-sponsored by APDBN, Jun 5, 2018
Microvillar tip-localized interaction between IRSp53 and PI(4,5)P2 drives brush border assembly in kidney epithelial cells.

Shusaku Kurisu, Toshiki Itoh, Tadaomi Takenawa

ASCB/IFCB annual meeting, Philadelphia, Dec 9, 2014, The American Society for Cell Biology
Regulation of renal brush border microvilli formation by the membrane-deforming activity of I-BAR domains

Shusaku Kurisu, Toshiki Itoh, Tadaomi Takenawa

The 56th Annual Meeting of the Japanese Conference on the Biochemistry of Lipids, Jun 6, 2014
IRSp53 family of I-BAR domain proteins regulates microvillius morphogenesis by sculpting the apical plasma membrane.

Shusaku Kurisu, Tadaomi Takenawa

The 65th Annual Meeting of the Japan Society for Cell Biology, Jun 20, 2013

Teaching Experience

Professional Memberships

The Japanese Biochemical Society
Japan Society for Cell Biology
Feb, 2017 - Present

The Japanese Society of Mechanobiology

Research Projects

蛍光タンパク質ノックインによる上皮メカノセンサーの分子数計測

Grants-in-Aid for Scientific Research, Apr, 2018 - Mar, 2021

栗栖修作
Molecular insight into the motile phenotype of the leader cells in epithelial collective migration

Grants-in-Aid for Scientific Research, Grant-in-Aid for Young Scientists (B), Japan Society for the Promotion of Science, Apr, 2013 - Mar, 2016

Kurisu Shusaku
三次元空間の細胞遊走におけるWASPファミリータンパク質の機能解析

科学研究費助成事業特別研究員奨励費, 特別研究員奨励費, 日本学術振興会, 2006 - 2007

栗栖修作

Profile Information

Research Interests

Research Areas

Research History

Education

Papers

Misc.

Books and Other Publications

Presentations

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