齋藤良一 (Ryoichi Saito) - マイポータル

基本情報

所属: 東京科学大学教育研究組織大学院生命理工医療科学専攻・生体検査科学講座微生物・感染免疫解析学分野教授

学位: 博士（保健学）
Doctor (Medical Laboratory Science)

研究者番号: 00581969
J-GLOBAL ID: 200901006374911070
researchmap会員ID: 5000091121

外部リンク: https://tmd-mmi.jp

研究キーワード

研究分野

経歴

2020年8月 - 現在

東京医科歯科大学, 大学院医歯学総合研究科生命理工医療科学専攻生体検査科学講座分子病原体検査学分野, 教授
2018年5月 - 現在

国立感染症研究所, 細菌第一部, 客員研究員
2018年4月 - 2020年7月

東京医科歯科大学, 大学院医歯学総合研究科生命理工医療科学専攻生体検査科学講座分子病原体検査学分野, 准教授
2012年5月 - 2018年3月

東京医科歯科大学, 大学院保健衛生学研究科生体検査科学専攻分子・遺伝子応用検査学講座生体防御検査学, 准教授
2015年11月 - 2017年3月

米国オレゴン州立大学, 獣医学部, 客員准教授
2010年4月 - 2013年3月

国立感染症研究所, 細菌第二部, 協力研究員
2010年4月 - 2012年4月

東京医科歯科大学, 大学院保健衛生学研究科生体検査科学専攻分子・遺伝子応用検査学講座生体防御検査学, 助教
2009年7月 - 2010年3月

国立感染症研究所, 細菌第二部, 研究員
1997年4月 - 2009年6月

東京大学医学部附属病院, 検査部・感染制御部, 臨床検査技師

主要な論文

155

Genomic and virulence characteristics of Brucella intermedia isolated from hospital wastewater in Ghana.

Runa Furuya, Satomi Takei, Yoko Tabe, Anthony Ablordey, Ryoichi Saito

Pathogens 14(6) 522 2025年5月査読有り
Emergence of high-level penicillin-resistant Neisseria meningitidis harboring ROB-1-type β-lactamase gene in Japan.

Hideyuki Takahashi, Yuki Ohama, Kazuhiro Horiba, Munehisa Fukusumi, Tomimasa Sunagawa, Tsukasa Ariyoshi, Mayako Koide, Ken Shimuta, Ryoichi Saito, Yukihiro Akeda

J Infect Chemother 31(4) 102679-102679 2025年3月査読有り
Emergence of Carbapenem-Resistant blaPOM-1 Harboring Pseudomonas otitidis Isolated from River Water in Ghana.

Frederick Ofosu Appiah, Samiratu Mahazu, Isaac Prah, Taira Kawamura, Yusuke Ota, Yohei Nishikawa, Mitsunori Yoshida, Masato Suzuki, Yoshihiko Hoshino, Toshihiko Suzuki …

Antibiotics (Basel) 14(1) 50 2025年1月査読有り
Metatranscriptomic Analysis Reveals Actively Expressed Antimicrobial-Resistant Genes and Their Hosts in Hospital Wastewater.

Yusuke Ota, Fei Chen, Isaac Prah, Samiratu Mahazu, Kimiyo Watanabe, Teruaki Kinoshita, Yoshiaki Gu, Yoko Nukui, Ryoichi Saito

Antibiotics (Basel) 13(12) 1122 2024年11月査読有り
Colistin Resistance Mediated by Mcr-3-Related Phosphoethanolamine Transferase Genes in Aeromonas Species Isolated from Aquatic Environments in Avaga and Pakro Communities in the Eastern Region of Ghana.

Samiratu Mahazu, Isaac Prah, Yusuke Ota, Takaya Hayashi, Masato Suzuki, Mitsunori Yoshida, Yoshihiko Hoshino, Yukihiro Akeda, Toshihiko Suzuki, Tomoko Ishino …

Infect Drug Resist 17 3011-3023 2024年7月査読有り
Molecular characterization of Staphylococcus epidermidis bloodstream isolates from two hospitals in Tokyo.

Kayo Yamada, Alafate Ayibieke, Akari Ikeda, Kageto Yamada, Shinji Ogihara, Shuji Tohda, Ryoichi Saito

Laboratory Medicine International 3(2) 33-41 2024年6月査読有り
Emergence of ciprofloxacin- and penicillin-resistant Neisseria meningitidis isolates in Japan between 2003 and 2020 and its genetic features.

Hideyuki Takahashi, Masatomo Morita, Hajime Kamiya, Munehisa Fukusumi, Mitsuru Yasuda, Masatomi Sunagawa, Haruna Nakamura-Miwa, Yuki Ohama, Ken Shimuta, Makoto Ohnishi …

Antimicrob Agents Chemother 67(11) e0074423-e0074423 2023年11月査読有り
Type A and F Clostridium perfringens in healthcare wastewater from Ghana.

Taira Kawamura, Isaac Prah, Samiratu Mahazu, Anthony Ablordey, Ryoichi Saito

Appl Environ Microbiol. 2023年10月査読有り最終著者責任著者
Novel insights into genetic characteristics of blaGES-encoding plasmids from hospital sewage.

Yusuke Ota, Isaac Prah, Samiratu Mahazu, Yoshiaki Gu, Yoko Nukui, Ryuji Koike, Ryoichi Saito

Front Microbiol 2023年8月査読有り最終著者責任著者
A mismatch amplification mutation assay for specific detection of ciprofloxacin-resistant Neisseria meningitidis.

Yusuke Ota, Reina Okada, Hideyuki Takahashi, Ryoichi Saito

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 2023年2月8日査読有り最終著者責任著者
Klebsiella Species and Enterobacter cloacae Isolates Harboring blaOXA-181 and blaOXA-48: Resistome, Fitness Cost, and Plasmid Stability.

Samiratu Mahazu, Isaac Prah, Yusuke Ota, Takaya Hayashi, Yoko Nukui, Masato Suzuki, Yoshihiko Hoshino, Yukihiro Akeda, Toshihiko Suzuki, Tomoko Ishino …

Microbiology spectrum 10(6) e0332022 2022年12月21日査読有り最終著者責任著者
Complete Genome Sequence of an Enterobacter roggenkampii Strain with Reduced Carbapenem Susceptibility Isolated from a Home-Visit Nursing Agency

Yusuke Ota, Chihiro Tani Sassa, Masayo Kashiwagi, Chikako Okawara, Shuji Tohda, Ryoichi Saito

Microbiology Resource Announcements 11(9) 2022年9月15日査読有り最終著者責任著者
Molecular detection of fluoroquinolone-resistant Neisseria meningitidis by using mismatched PCR-restriction fragment length polymorphism technique

Yusuke Ota, Reina Okada, Hideyuki Takahashi, Ryoichi Saito

Frontiers in Cellular and Infection Microbiology 12 911911-911911 2022年8月2日査読有り最終著者責任著者
Penicillin- and Ciprofloxacin-Resistant Invasive Neisseria meningitidis Isolates from Japan.

Ryoichi Saito, Jun Nakajima, Isaac Prah, Masatomo Morita, Samiratu Mahazu, Yusuke Ota, Ayuka Kobayashi, Shuji Tohda, Hajime Kamiya, Hideyuki Takahashi …

Microbiology spectrum 10(3) e0062722 2022年6月29日査読有り筆頭著者責任著者
Emergence of a High-Risk Klebsiella michiganensis Clone Disseminating Carbapenemase Genes

Isaac Prah, Yoko Nukui, Shoji Yamaoka, Ryoichi Saito

Frontiers in Microbiology 13 880248-880248 2022年5月23日査読有り最終著者責任著者
blaKPC-2-Encoding IncP-6 Plasmids in Citrobacter freundii and Klebsiella variicola Strains from Hospital Sewage in Japan.

Yusuke Ota, Isaac Prah, Yoko Nukui, Ryuji Koike, Ryoichi Saito

Applied and environmental microbiology 88(8) e0001922 2022年4月26日査読有り最終著者責任著者
Insights and genetic features of extended-spectrum beta-lactamase producing Escherichia coli isolates from two hospitals in Ghana.

Samiratu Mahazu, Wakana Sato, Alafate Ayibieke, Isaac Prah, Takaya Hayashi, Toshihiko Suzuki, Shiroh Iwanaga, Anthony Ablordey, Ryoichi Saito

Scientific reports 12(1) 1843-1843 2022年2月3日査読有り最終著者責任著者
Emergence of oxacillinase-181 carbapenemase-producing diarrheagenic Escherichia coli in Ghana.

Isaac Prah, Alafate Ayibieke, Samiratu Mahazu, Chihiro Tani Sassa, Takaya Hayashi, Shoji Yamaoka, Toshihiko Suzuki, Shiroh Iwanaga, Anthony Ablordey, Ryoichi Saito

Emerging microbes & infections 10(1) 865-873 2021年12月査読有り最終著者責任著者
Development of a simple and cost-effective gel-based duplex PCR method to identify both encapsulated and unencapsulated Neisseria meningitidis applicable under resource-limited conditions.

Hideyuki Takahashi, Masaki Nakamura, Yuko Matsumoto, Shuji Yoshino, Tetsuya Kakita, Ken Shimuta, Hajime Kamiya, Ryoichi Saito, Makoto Ohnishi

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 27(5) 773-777 2021年5月
Virulence Profiles of Diarrheagenic Escherichia coli Isolated from the Western Region of Ghana.

Isaac Prah, Alafate Ayibieke, Thi Thu Huong Nguyen, Atsushi Iguchi, Samiratu Mahazu, Wakana Sato, Takaya Hayashi, Shoji Yamaoka, Toshihiko Suzuki, Shiroh Iwanaga …

Jpn J Infect Dis 74(2) 115-121 2021年3月査読有り最終著者責任著者
Possible Dissemination of Escherichia coli Sequence Type 410 Closely Related to B4/H24RxC in Ghana.

Samiratu Mahazu, Isaac Prah, Alafate Ayibieke, Wakana Sato, Takaya Hayashi, Toshihiko Suzuki, Shiroh Iwanaga, Anthony Ablordey, Ryoichi Saito

Frontiers in microbiology 12 770130-770130 2021年査読有り最終著者責任著者
市販輸送培地におけるNeisseria meningitidis生菌数の経時的変動．

小林亜由香, 中島淳, 大塚武, 飯草正実, 酒井雄一郎, 佐多章, 大城健哉, 菊地孝司, 菊池俊, 松本裕 …

日本臨床微生物学雑誌 31(2) 108-112 2021年1月査読有り最終著者責任著者
Evaluation of polymerase chain reaction-based open reading frame typing method for the clonality investigation of Clostridioides difficile isolates.

Yusuke Ota, Natsune Hongou, Yoko Nukui, Ryuji Koike, Shuji Tohda, Ryoichi Saito

Anaerobe 72 102462-102462 2021年査読有り最終著者責任著者
Prevalence and characterization of carbapenem-hydrolyzing class D β-lactamase-producing Acinetobacter isolates from Ghana.

Alafate Ayibieke, Ayumi Kobayashi, Masato Suzuki, Wakana Sato, Samiratu Mahazu, Isaac Prah, Miyuki Mizoguchi, Kyoji Moriya, Takaya Hayashi, Toshihiko Suzuki …

Front Microbiol 11 587398-587398 2020年11月査読有り最終著者責任著者
Genetic Diversity and Epidemiology of Accessory Gene Regulator Loci in Clostridioides difficile.

Yuta Okada, SHU OKUGAWA, Mahoko Ikeda, Tatsuya Kobayashi, Ryoichi Saito, Yoshimi Higurashi, Kyoji Moriya

Access Microbiology 2(7) acmi000134 2020年5月査読有り
Draft Genome Sequence of a Clostridioides difficile Sequence Type 97 Strain Belonging to Hypervirulent Clade 2.

Yukino Usui, Yoko Nukui, Ryuji Koike, Shuji Tohda, Ryoichi Saito

Microbiology resource announcements 9(14) e00245-20 2020年4月2日査読有り最終著者責任著者
Impact of deoxycholate on Clostridioides difficile growth, toxin production, and sporulation.

Yukino Usui, Alafate Ayibieke, Yuko Kamiichi, Shu Okugawa, Kyoji Moriya, Shuji Tohda, Ryoichi Saito

Heliyon 6(4) e03717-e03717 2020年4月査読有り最終著者責任著者
Gene Composition as a Potential Barrier to Large Recombinations in the Bacterial Pathogen Klebsiella pneumoniae.

Francesco Comandatore, Davide Sassera, Sion C Bayliss, Erika Scaltriti, Stefano Gaiarsa, Xiaoli Cao, Ana C Gales, Ryoichi Saito, Stefano Pongolini, Sylvain Brisse …

Genome Biol Evol 11(11) 3240-3251 2019年11月査読有り
Long-term observation of antimicrobial susceptibility and molecular characterisation of Campylobacter jejuni isolated in a Japanese general hospital 2000-2017.

Kageto Yamada, Ryoichi Saito, Saori Muto, Masakazu Sasaki, Hinako Murakami, Kotaro Aoki, Yoshikazu Ishii, Kazuhiro Tateda

Journal of global antimicrobial resistance 18 59-63 2019年9月査読有り
Whole-genome analysis of EC129, an NDM-5-, CTX-M-14-, OXA-10- and MCR-1-co-producing Escherichia coli ST167 strain isolated from Japan.

Yoko Nukui, Alafate Ayibieke, Makoto Taniguchi, Yoshibumi Aiso, Yuka Shibuya, Kazunari Sonobe, Jun Nakajima, Saki Kanehira, Yoshiro Hadano, Shuji Tohda …

Journal of global antimicrobial resistance 18 148-150 2019年9月査読有り
Hypervirulent clade 2, ribotype 019/sequence type 67 Clostridioides difficile strain from Japan.

Ryoichi Saito, Yukino Usui, Alafate Ayibieke, Jun Nakajima, Isaac Prah, Kazunari Sonobe, Yoshibumi Aiso, Shiori Ito, Yasuhiro Itsui, Yoshiro Hadano …

Gut pathogens 11 54-54 2019年査読有り
Molecular characterisation of the NDM-1-encoding plasmid p2189-NDM in an Escherichia coli ST410 clinical isolate from Ghana.

Alafate Ayibieke, Wakana Sato, Samiratu Mahazu, Isaac Prah, John Addow-Thompson, Mitsuko Ohashi, Toshihiko Suzuki, Shiroh Iwanaga, Anthony Ablordey, Ryoichi Saito

PLoS ONE 13(12) e0209623-e0209623 2018年12月査読有り
RelA/DTD-mediated regulation of spore formation and toxin production by Clostridium perfringens type A strain SM101

Ryoichi Saito, Prabhat K. Talukdar, Saud S. Alanazi, Mahfuzur R. Sarker

Microbiology (United Kingdom) 164(5) 835-847 2018年5月1日査読有り
Novel mechanism responsible for high-level macrolide resistance in Moraxella catarrhalis.

Ayako Kasai, Ayaka Ohta, Yuina Maeda, Kageto Yamada, Kazuyuki Tao, Ryoichi Saito

Infection and drug resistance 11 2137-2140 2018年査読有り
Molecular Characterization of Fluoroquinolone-Resistant Moraxella catarrhalis Variants Generated in Vitro by Stepwise Selection

Kageto Yamada, Ryoichi Saito, Saori Muto, Machiko Kashiwa, Yoshiko Tannamori, Shingo Fujisaki

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 61(10) 2017年10月査読有り
Molecular Characterization of Fluoroquinolone-Resistant Moraxella catarrhalis Variants Generated In Vitro by Stepwise Selection.

Kageto Yamada, Ryoichi Saito, Saori Muto, Machiko Kashiwa, Yoshiko Tamamori, Shingo Fujisaki

Antimicrobial agents and chemotherapy 61(10) e01336-17 2017年10月査読有り
Antimicrobial susceptibility to β-lactam antibiotics and production of BRO β-lactamase in clinical isolates of Moraxella catarrhalis from a Japanese hospital.

Yamada K, Arai K, Saito R

Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 50(3) 386-389 2017年6月査読有り
Antimicrobial susceptibility to β-lactam antibiotics and production of BRO β-lactamase in clinical isolates of Moraxella catarrhalis from a Japanese hospital.

Kageto Yamada, Katsumi Arai, Ryoichi Saito

J Microbiol Immunol Infect 50(3) 386-389 2017年6月1日査読有り
Evaluation of the modified carbapenem inactivation method and sodium mercaptoacetate-combination method for the detection of metallo-β-lactamase production by carbapenemase-producing Enterobacteriaceae.

Yamada K, Kashiwa M, Arai K, Nagano N, Saito R

Journal of microbiological methods 132 112-115 2017年1月査読有り
Evaluation of the modified carbapenem inactivation method and sodium mercaptoacetate-combination method for the detection of metallo-β-lactamase production by carbapenemase-producing Enterobacteriaceae.

Kageto Yamada, Machiko Kashiwa, Katsumi Arai, Noriyuki Nagano, Ryoichi Saito

J. Microbiol. Methods 132 112-115 2017年1月査読有り
Comparison of agar dilution and broth microdilution methods for Clostridium difficile antimicrobial susceptibility testing

Gene Igawa, Mika Casey, Etsuko Sawabe, Yoko Nukui, Shu Okugawa, Kyoji Moriya, Ryuji Koike, Shuji Tohda, Ryoichi Saito

Journal of Global Antimicrobial Resistance 7 43-45 2016年12月1日査読有り
A Highly Macrolide-Resistant Campylobacter jejuni Strain with Rare A2074T Mutations in 23S rRNA Genes.

Hiroe Ohno, Jun-Ichi Wachino, Ryoichi Saito, Wanchun Jin, Keiko Yamada, Kouji Kimura, Yoshichika Arakawa

Antimicrobial agents and chemotherapy 60(4) 2580-1 2016年4月査読有り
Rapid assay of A2058T-mutated 23S rRNA allelic profiles associated with high-level macrolide resistance in Moraxella catarrhalis.

Ryoichi Saito, Ayako Kasai, Shinji Ogihara, Kageto Yamada, Kazuyuki Tao

Journal of medical microbiology 64(9) 990-992 2015年9月査読有り
The outer membrane protein CD is associated with resistance to penicillins in Moraxella catarrhalis

Ryoichi Saito, Yuta Miharu, Shiho Matsuoka, Shotaro Nonaka, Yuji Fujinami, Noboru Okamura

JOURNAL OF GLOBAL ANTIMICROBIAL RESISTANCE 3(3) 224-225 2015年9月査読有り
Prevalence and molecular analysis of macrolide-resistant Moraxella catarrhalis clinical isolates in Japan, following emergence of the highly macrolide-resistant strain NSH1 in 2011.

Ayako Kasai, Shinji Ogihara, Kageto Yamada, Yumiko Tanimichi, Hiroyuki Nishiyama, Ryoichi Saito

Journal of medical microbiology 64(7) 708-713 2015年7月査読有り