論文

査読有り
2013年

Blood viscometer applying electromagnetically spinning method

Journal of Artificial Organs
  • Kazuyoshi Fukunaga
  • ,
  • Masaya Onuki
  • ,
  • Yoshinori Ohtsuka
  • ,
  • Taichi Hirano
  • ,
  • Keiji Sakai
  • ,
  • Yasuharu Ohgoe
  • ,
  • Ayako Katoh
  • ,
  • Toshiyuki Yaguchi
  • ,
  • Akio Funakubo
  • ,
  • Yasuhiro Fukui

16
3
開始ページ
359
終了ページ
367
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1007/s10047-013-0707-3

Viscosity is an important parameter which affects hemodynamics during extracorporeal circulation and long-term cardiac support. In this study, we have aimed to develop a novel viscometer with which we can easily measure blood viscosity by applying the electromagnetically spinning (EMS) method. In the EMS method, we can rotate an aluminum ball 2 mm in diameter indirectly in a test tube with 0.3 ml sample of a liquid by utilizing the moment caused by the Lorentz force as well as separate the test tube from the viscometer body. First, we calibrated the EMS viscometer by means of liquid samples with known viscosities and computational fluid dynamics. Then, when we measured the viscosity of 9.4 mPa s silicone oil in order to evaluate the performance of the EMS viscometer, the mean viscosity was found to be 9.55 ± 0.10 mPa s at available shear rates from 10 to 240 s-1. Finally, we measured the viscosity of bovine blood. We prepared four blood samples whose hematocrit levels were adjusted to 23, 45, 50, and 70 % and a plasma sample without hemocyte components. As a result, the measurements of blood viscosities showed obedience to Casson's equation. We found that the viscosity was approximately constant in Newtonian silicone oil, whereas the viscosity decreased with increasing shear rate in non-Newtonian bovine blood. These results suggest that the EMS viscometer will be useful to measure blood viscosity at the clinical site. © 2013 The Japanese Society for Artificial Organs.

リンク情報
DOI
https://doi.org/10.1007/s10047-013-0707-3
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/23575974
ID情報
  • DOI : 10.1007/s10047-013-0707-3
  • ISSN : 1434-7229
  • ISSN : 1619-0904
  • PubMed ID : 23575974
  • SCOPUS ID : 84885429556

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