ISHIMI Yukio

J-GLOBAL         Last updated: May 30, 2019 at 10:44
 
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Name
ISHIMI Yukio
Research funding number
80159772

Profile

(研究経歴)
1. Structure of nucleosome and nucleosome assembly factor
2. Reconstitution of SV40 DNA replication in vitro
3. Establishment of model DNA replication system
4. Structure and function of MCM proteins

Research Areas

 
 

Academic & Professional Experience

 
 
   
 
Professor, Ibaraki University Graduate School of Science and Engineering (Science), Department of Science (Biological Sciences Course)
 
Jul 1983
 - 
Aug 1988
assistant professor, Faculty of Pharmaceutical Sciences, University of Tokyo
 
Sep 1988
 - 
Sep 2004
member, Mitsubishi Kagaku Institute of Life Sciences
 
Oct 2004
   
 
Prof. Faculty of Science, Ibaraki University
 

Published Papers

 
Wang, X. and Ishimi, Y.
J. Biochem.   164 449-460   Sep 2018   [Refereed]
Effect of daidzein and equal on DNA replication in MCF-7 cells
Tsuji, M., Tanaka, T., Nagashima, R., Sagisaka, Y., Tosen, Y., Nishide, Y., Ishimi, Y. and ishimi, Y.
J. Biochem.   163 371-380   Jan 2018   [Refereed]
An MCM4 mutation detected in cancer cells affects MCM4/6/7 complex formation.
Tatsumi, R. and Ishimi, Y.
J. Biochem.   161 259-268   2017   [Refereed]
Binding of MCM-interacting proteins to ATP-binding site in MCM6
Hosoi, A., Sakairi, T. and Ishimi, Y.
Research Reports in Biology   7 31-40   2016   [Refereed]
G364R mutation of MCM4 detected in human skin cancer cells affects DNA helicase activity of MCM4/6/7 complex
Ishimi, Y. and Irie, D.
J. Biochem.   157(6) 561-569   Feb 2015   [Refereed]

Misc

 
Ishimi, Y.
Genes Genet. System.   93 125-133   Aug 2018   [Refereed][Invited]

Conference Activities & Talks

 
MCM相互作用因子はMCM6のATP結合部位に結合する
細井淳駿、酒入拓、石見幸男
第39回日本分子生物学会年会   2 Dec 2016   
MCMヘリカーゼの保存性と多様性 [Invited]
石見幸男
日本進化学会第18回東京大会   25 Aug 2016   
ヒトRPAに直接的に相互作用するタンパク質の同定
中谷亮、野崎直人、石見幸男
日本分子生物学会年会   11 Dec 2009   
乳がんを引き起こすMCM4タンパク質変異の解析
渡辺瑛美、石見幸男
日本分子生物学会年会   11 Dec 2009   
ヒトMCM-BPタンパク質の機能解析
昆良子、野崎直人、石見幸男
日本分子生物学会年会   11 Dec 2009   

Research Grants & Projects

 
MCMを中心としたDNA複製因子の集合と機能抑制機構の解明
日本学術振興会: 
Project Year: Apr 2014 - Mar 2017    Investigator(s): 石見幸男
DNA複製フォークでの分子集合と複製ヘリカーゼの役割の解明
Project Year: Apr 2011 - Mar 2013
MCMヘリカーゼ機能発現調節機構の解明
Project Year: Apr 2005 - Mar 2008