Misc.

International journal
Jun, 2012

Phrenic Nerve Injury after Radiofrequency Ablation of Lung Tumors: Retrospective Evaluation of the Incidence and Risk Factors

JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
  • Yusuke Matsui
  • ,
  • Takao Hiraki
  • ,
  • Hideo Gobara
  • ,
  • Mayu Uka
  • ,
  • Yoshihisa Masaoka
  • ,
  • Akihiro Tada
  • ,
  • Shinichi Toyooka
  • ,
  • Toshiharu Mitsuhashi
  • ,
  • Hidefumi Mimura
  • ,
  • Susumu Kanazawa

Volume
23
Number
6
First page
780
Last page
785
Language
English
Publishing type
DOI
10.1016/j.jvir.2012.02.014
Publisher
ELSEVIER SCIENCE INC

Purpose: To retrospectively investigate the incidence of and risk factors for phrenic nerve injury after radiofrequency (RF) ablation of lung tumors.
Materials and Methods: The study included 814 RF ablation procedures of lung tumors. To evaluate the development of phrenic nerve injury, chest radiographs obtained before and after the procedure were examined. Phrenic nerve injury was assumed to have developed if the diaphragmatic level was elevated after the procedure. To identify risk factors for phrenic nerve injury, multiple variables were compared between cases of phrenic nerve injury and randomly selected controls by using univariate analyses. Multivariate analysis was then performed to identify independent risk factors.
Results: Evaluation of phrenic nerve injury from chest radiographs was possible after 786 procedures. Evidence of phrenic nerve injury developed after 10 cases (1.3%). Univariate analysis revealed that larger tumor size >= 20 mm; P = .014), proximity of the phrenic nerve to the tumor (< 10 mm; P < .001), the use of larger electrodes (array diameter or noninsulated tip length >= 3 cm; P = .001), and higher maximum power applied during ablation (>= 100 W; P < .001) were significantly associated with the development of phrenic nerve injury. Multivariate analysis demonstrated that the proximity of the phrenic nerve to the tumor (< 10 mm; P < .001) was a significant independent risk factor.
Conclusions: The incidence of phrenic nerve injury after RF ablation was 1.3%. The proximity of the phrenic nerve to the tumor was an independent risk factor for phrenic nerve injury.

Link information
DOI
https://doi.org/10.1016/j.jvir.2012.02.014
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/22513393
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000304691400008&DestApp=WOS_CPL
ID information
  • DOI : 10.1016/j.jvir.2012.02.014
  • ISSN : 1051-0443
  • Pubmed ID : 22513393
  • Web of Science ID : WOS:000304691400008

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