論文

最終著者
2020年4月

Juvenile Granulosa Cell Tumor with an Unusual Clinical Course: A Late-onset and Late Recurrent Case.

Acta medica Okayama
  • Thar Htet San
  • ,
  • Yoko Ota
  • ,
  • Soichiro Fushimi
  • ,
  • Masayoshi Fujisawa
  • ,
  • Hiroyuki Yanai
  • ,
  • Hiroko Toda
  • ,
  • Tadayoshi Kunitomo
  • ,
  • Keisuke Kodama
  • ,
  • Akihiro Matsukawa

74
2
開始ページ
159
終了ページ
163
記述言語
英語
掲載種別
DOI
10.18926/AMO/58275

Juvenile granulosa cell tumors (JGCTs) are rare ovarian tumors with overall good prognoses. They differ from adult granulosa cell tumors (AGCTs), which are well known for late recurrence. Most JGCTs (~97%) occur in individuals <30 years old. We report a recurrent JGCT in a 40-year-old woman 5 years after initial presentation. The histological appearance and lack of 402C>G missense point mutation of FOXL2 gene (characteristic of AGCT but absent in JGCT) allowed differentiation from AGCT. This is the first comprehensive report of JGCT with late recurrence. Although rare, late recurrence of JGCT can occur; long-term surveillance is suggested.

リンク情報
DOI
https://doi.org/10.18926/AMO/58275
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/32341591
ID情報
  • DOI : 10.18926/AMO/58275
  • PubMed ID : 32341591

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