2020年4月
Juvenile Granulosa Cell Tumor with an Unusual Clinical Course: A Late-onset and Late Recurrent Case.
Acta medica Okayama
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- 巻
- 74
- 号
- 2
- 開始ページ
- 159
- 終了ページ
- 163
- 記述言語
- 英語
- 掲載種別
- DOI
- 10.18926/AMO/58275
Juvenile granulosa cell tumors (JGCTs) are rare ovarian tumors with overall good prognoses. They differ from adult granulosa cell tumors (AGCTs), which are well known for late recurrence. Most JGCTs (~97%) occur in individuals <30 years old. We report a recurrent JGCT in a 40-year-old woman 5 years after initial presentation. The histological appearance and lack of 402C>G missense point mutation of FOXL2 gene (characteristic of AGCT but absent in JGCT) allowed differentiation from AGCT. This is the first comprehensive report of JGCT with late recurrence. Although rare, late recurrence of JGCT can occur; long-term surveillance is suggested.
- ID情報
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- DOI : 10.18926/AMO/58275
- PubMed ID : 32341591