2020年3月
Effect of refrigeration of blood samples in lithium-heparin tubes on QuantiFERON TB Gold Plus test result
Journal of Infection and Chemotherapy
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- 巻
- 26
- 号
- 3
- 開始ページ
- 312
- 終了ページ
- 314
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1016/j.jiac.2019.10.002
- 出版者・発行元
- Journal of Infection and Chemotherapy
© 2019 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases The QuantiFERON TB Gold Plus (QFT-Plus) test is a newly approved interferon-gamma releasing assay test for detecting latent tuberculosis. Although blood samples for QFT test can be refrigerated for 48 h in lithium-heparin tubes according to package inserts, no published data are available on the effects of sample refrigeration on the test results. We conducted a clinical study that aimed to elucidate whether sample refrigeration for 48 h affects QFT-Plus test results. We collected 2 blood samples each from 40 participants for QFT-Plus; one sample was refrigerated before incubation for QFT-Plus assay, while the other sample was incubated soon after collection and treated as control. After comparing QFT-Plus test results of refrigerated samples and control samples, the concordance rate and kappa coefficient between them were 95% and 0.90, respectively. Thus, blood samples for QFT-Plus test can be refrigerated for 48 h in lithium-heparin tubes without influencing the test results.
- リンク情報
- ID情報
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- DOI : 10.1016/j.jiac.2019.10.002
- ISSN : 1341-321X
- PubMed ID : 31836288