藤本崇宏 (Takahiro Fujimoto) - マイポータル

基本情報

J-GLOBAL ID: 200901038774653983
researchmap会員ID: 5000104529

研究キーワード

研究分野

受賞

2010年

第12回福岡大学医学会賞金賞, 福岡大学医学会

藤本崇宏

論文

Leukemia inhibitory factor shortens primary cilia by upregulating C-C motif chemokine 2 in human neural stem/progenitor cells.

Hisashi Takahashi, Takahiro Fujimoto, Takeshi Yaoi, Shinji Fushiki, Kyoko Itoh

Genes to cells : devoted to molecular & cellular mechanisms 2023年10月14日査読有り
Myosin Va, a Novel Interaction Partner of STXBP1, Is Required to Transport Syntaxin1A to the Plasma Membrane.

Yoshihiro Taura, Takenori Tozawa, Takahiro Fujimoto, Eisuke Ichise, Tomohiro Chiyonobu, Kyoko Itoh, Tomoko Iehara

Neuroscience 524 256-268 2023年8月1日査読有り
Dystrophin Short Product, Dp71, Interacts with AQP4 and Kir4.1 Channels in the Mouse Cerebellar Glial Cells in Contrast to Dp427 at Inhibitory Postsynapses in the Purkinje Neurons.

Takahiro Fujimoto, Kirsten Stam, Takeshi Yaoi, Kenta Nakano, Tetsuya Arai, Tadashi Okamura, Kyoko Itoh

Molecular neurobiology 60(7) 3664-3677 2023年3月15日査読有り筆頭著者責任著者
Low Doses of Bisphenol A Disrupt Neuronal Differentiation of Human Neuronal Stem/Progenitor Cells.

Kaori Kiso-Farnè, Takeshi Yaoi, Takahiro Fujimoto, Kyoko Itoh

Acta histochemica et cytochemica 55(6) 193-202 2022年12月28日査読有り
Generation of dystrophin short product-specific tag-insertion mouse: distinct Dp71 glycoprotein complexes at inhibitory postsynapse and glia limitans.

Takahiro Fujimoto, Takeshi Yaoi, Kenta Nakano, Tetsuya Arai, Tadashi Okamura, Kyoko Itoh

Cellular and molecular life sciences : CMLS 79(2) 109-109 2022年1月30日査読有り筆頭著者
Dystroglycan regulates proper expression, submembranous localization and subsequent phosphorylation of Dp71 through physical interaction.

Takahiro Fujimoto, Takeshi Yaoi, Hidekazu Tanaka, Kyoko Itoh

Human molecular genetics 29(19) 3312-3326 2020年9月30日査読有り筆頭著者
Dp71 is regulated by phosphorylation and ubiquitin-proteasome system in neuronal cells

Takahiro Fujimoto, Takeshi Yaoi, Shinji Fushiki, Kyoko Itoh

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 492(3) 349-355 2017年10月査読有り筆頭著者
Extensive Ca2+ leak through K4750Q cardiac ryanodine receptors caused by cytosolic and luminal Ca2+ hypersensitivity

Akira Uehara, Takashi Murayama, Midori Yasukochi, Michael Fill, Minoru Horie, Toru Okamoto, Yoshiharu Matsuura, Kiyoko Uehara, Takahiro Fujimoto, Takashi Sakurai …

JOURNAL OF GENERAL PHYSIOLOGY 149(2) 199-218 2017年2月査読有り
HEK293 cells express dystrophin Dp71 with nucleus-specific localization of Dp71ab

Atsushi Nishida, Sato Yasuno, Atsuko Takeuchi, Hiroyuki Awano, Tomoko Lee, Emma Tabe Eko Niba, Takahiro Fujimoto, Kyoko Itoh, Yasuhiro Takeshima, Hisahide Nishio …

HISTOCHEMISTRY AND CELL BIOLOGY 146(3) 301-309 2016年9月査読有り
Marked Reduction in FoxO1 Protein by its Enhanced Proteasomal Degradation in Zfat-deficient Peripheral T-Cells

Yuri Iwaihara, Shuhei Ishikura, Keiko Doi, Toshiyuki Tsunoda, Takahiro Fujimoto, Tadashi Okamura, Senji Shirasawa

ANTICANCER RESEARCH 35(8) 4419-4423 2015年8月査読有り
Somatodendritic and excitatory postsynaptic distribution of neuron-type dystrophin isoform, Dp40, in hippocampal neurons

Takahiro Fujimoto, Kyoko Itoh, Takeshi Yaoi, Shinji Fushiki

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 452(1) 79-84 2014年9月査読有り筆頭著者
MDR1 C3435T Polymorphism and Interaction with Environmental Factors in Risk of Parkinson's Disease: A Case-control Study in Japan

Chikako Kiyohara, Yoshihiro Miyake, Midori Koyanagi, Takahiro Fujimoto, Senji Shirasawa, Keiko Tanaka, Wakaba Fukushima, Satoshi Sasaki, Yoshio Tsuboi, Tatsuo Yamada …

DRUG METABOLISM AND PHARMACOKINETICS 28(2) 138-143 2013年4月査読有り
Tespa1 is a novel component of mitochondria-associated endoplasmic reticulum membranes and affects mitochondrial calcium flux

Hiroshi Matsuzaki, Takahiro Fujimoto, Masatoshi Tanaka, Senji Shirasawa

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 433(3) 322-326 2013年4月査読有り
Tespa1 protein is phosphorylated in response to store-operated calcium entry

Takahiro Fujimoto, Hiroshi Matsuzaki, Masatoshi Tanaka, Senji Shirasawa

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 434(1) 162-165 2013年4月査読有り筆頭著者

MISC

神経型ジストロフィンの分子病態解析に基づく知的障害治療法の探索

藤本崇宏, 伊東恭子

日本小児科学会雑誌 121(2) 2017年
Identification of KRAP-expressing cells and the functional relevance of KRAP to the subcellular localization of IP3R in the stomach and kidney

Takahiro Fujimoto, Senji Shirasawa

International Journal of Molecular Medicine 30(6) 1287-1293 2012年12月査読有り筆頭著者
High expression of the longevity gene product SIRT1 and apoptosis induction by sirtinol in adult T-cell leukemia cells

Tomohiro Kozako, Akiyoshi Aikawa, Teruhisa Shoji, Takahiro Fujimoto, Makoto Yoshimitsu, Senji Shirasawa, Hiroaki Tanaka, Shin-Ichiro Honda, Hiroshi Shimeno, Naomichi Arima …

International Journal of Cancer 131(9) 2044-2055 2012年11月1日
ZFAT plays critical roles in peripheral T cell homeostasis and its T cell receptor-mediated response

Keiko Doi, Takahiro Fujimoto, Tadashi Okamura, Masahiro Ogawa, Yoko Tanaka, Yasumasa Mototani, Motohito Goto, Takeharu Ota, Hiroshi Matsuzaki, Masahide Kuroki …

Biochemical and Biophysical Research Communications 425(1) 107-112 2012年8月17日
Inhibition of Phosphodiesterase-4 (PDE4) activity triggers luminal apoptosis and AKT dephosphorylation in a 3-D colonic-crypt model

Toshiyuki Tsunoda, Takeharu Ota, Takahiro Fujimoto, Keiko Doi, Yoko Tanaka, Yasuhiro Yoshida, Masahiro Ogawa, Hiroshi Matsuzaki, Masato Hamabashiri, Darren R. Tyson …

Molecular Cancer 11(1) 46 2012年7月25日
KRAS up-regulates the expression of miR-181a, miR-200c and miR-210 in a three-dimensional-specific manner in DLD-1 colorectal cancer cells

Takeharu Ota, Keiko Doi, Takahiro Fujimoto, Yoko Tanaka, Masahiro Ogawa, Hiroshi Matsuzaki, Masahide Kuroki, Shingo Miyamoto, Senji Shirasawa, Toshiyuki Tsunoda

Anticancer Research 32(6) 2271-2276 2012年6月
ALPK2 is Crucial for luminal apoptosis and DNA repair-related gene expression in a three-dimensional colonic-crypt model

Yasuhiro Yoshida, Toshiyuki Tsunoda, Keiko Doi, Takahiro Fujimoto, Yoko Tanaka, Takeharu Ota, Masahiro Ogawa, Hiroshi Matsuzaki, Masahide Kuroki, Akinori Iwasaki …

Anticancer Research 32(6) 2301-2308 2012年6月
Tespa1 is a novel inositol 1,4,5-trisphosphate receptor binding protein in T and B lymphocytes

Hiroshi Matsuzaki, Takahiro Fujimoto, Takeharu Ota, Masahiro Ogawa, Toshiyuki Tsunoda, Keiko Doi, Masato Hamabashiri, Masatoshi Tanaka, Senji Shirasawa

FEBS Open Bio 2 255-259 2012年
APOE and CYP2E1 polymorphisms, alcohol consumption, and Parkinson's disease in a Japanese population

Chikako Kiyohara, Yoshihiro Miyake, Midori Koyanagi, Takahiro Fujimoto, Senji Shirasawa, Keiko Tanaka, Wakaba Fukushima, Satoshi Sasaki, Yoshio Tsuboi, Tatsuo Yamada …

Journal of Neural Transmission 118(9) 1335-1344 2011年9月
Genetic polymorphisms involved in dopaminergic neurotransmission and risk for Parkinson's disease in a Japanese population

Chikako Kiyohara, Yoshihiro Miyake, Midori Koyanagi, Takahiro Fujimoto, Senji Shirasawa, Keiko Tanaka, Wakaba Fukushima, Satoshi Sasaki, Yoshio Tsuboi, Tatsuo Yamada …

BMC Neurology 11(1) 89 2011年7月25日
KRAS-mediated Up-regulation of RRM2 Expression Is Essential for the Proliferation of Colorectal Cancer Cell Lines

Yasuhiro Yoshida, Toshiyuki Tsunoda, Keiko Doi, Yoko Tanaka, Takahiro Fujimoto, Takashi Machida, Takeharu Ota, Midori Koyanagi, Yasuo Takashima, Takehiko Sasazuki …

ANTICANCER RESEARCH 31(7) 2535-2539 2011年7月
KRAS-induced actin-interacting protein: A potent target for obesity, diabetes and cancer

Takahiro Fujimoto, Senji Shirasawa

Anticancer Research 31(7) 2413-2418 2011年7月
KRAS-mediated up-regulation of RRM2 expression is essential for the proliferation of colorectal cancer cell lines

Yasuhiro Yoshida, Toshiyuki Tsunoda, Keiko Doi, Yoko Tanaka, Takahiro Fujimoto, Takashi Machida, Takeharu Ota, Midori Koyanagi, Yasuo Takashima, Takehiko Sasazuki …

Anticancer Research 31(7) 2535-2539 2011年7月
Oncogenic KRAS regulates miR-200c and miR-221/222 in a 3D-specific manner in colorectal cancer cells

Toshiyuki Tsunoda, Yasuo Takashima, Yasuhiro Yoshida, Keiko Doi, Yoko Tanaka, Takahiro Fujimoto, Takashi Machida, Takeharu Ota, Midori Koyanagi, Masahide Kuroki …

Anticancer Research 31(7) 2453-2459 2011年7月
Determination of the critical region of KRAS-induced actin-interacting protein for the interaction with inositol 1,4,5-trisphosphate receptor

Takahiro Fujimoto, Takashi Machida, Toshiyuki Tsunoda, Keiko Doi, Takeharu Ota, Masahide Kuroki, Senji Shirasawa

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 408(2) 282-286 2011年5月
KRAS-induced actin-interacting protein regulates inositol 1,4,5-trisphosphate-receptor-mediated calcium release

Takahiro Fujimoto, Takashi Machida, Toshiyuki Tsunoda, Keiko Doi, Takeharu Ota, Masahide Kuroki, Senji Shirasawa

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 408(2) 214-217 2011年5月
KRAS-induced actin-interacting protein is required for the proper localization of inositol 1,4,5-trisphosphate receptor in the epithelial cells

Takahiro Fujimoto, Takashi Machida, Yoko Tanaka, Toshiyuki Tsunoda, Keiko Doi, Takeharu Ota, Tadashi Okamura, Masahide Kuroki, Senji Shirasawa

Biochemical and Biophysical Research Communications 407(2) 438-443 2011年4月8日
Case-control study of eczema associated with IL13 genetic polymorphisms in Japanese children

Yoshihiro Miyake, Chikako Kiyohara, Midori Koyanagi, Takahiro Fujimoto, Senji Shirasawa, Keiko Tanaka, Satoshi Sasaki, Yoshio Hirota

International Archives of Allergy and Immunology 154(4) 328-335 2011年3月
Zfat is a critical molecule for cell survival in mouse Embryonic Fibroblasts

Keiko Doi, Takahiro Fujimoto, Midori Koyanagi, Toshiyuki Tsunoda, Yoko Tanaka, Yasuhiro Yoshida, Yasuo Takashima, Masahide Kuroki, Takehiko Sasazuki, Senji Shirasawa

Cellular and Molecular Biology Letters 16(1) 89-100 2011年
Genetic polymorphisms involved in dopaminergic neurotransmission and risk for Parkinson's disease in a Japanese population.

Kiyohara C, Miyake Y, Koyanagi M, Fujimoto T, Shirasawa S, Tanaka K, Fukushima W, Sasaki S, Tsuboi Y, Yamada T …

BMC Neurol. 11(1) 89 2011年