論文

2020年10月

Modification of the Release Rate of Curcumin from the Cavity of Renatured beta-1,3-1,6-Glucan Nanoparticles by Changing the Molecular Weight of the Constituent Polysaccharide Chains

CHEMISTRY LETTERS
  • Yuki Nonoguchi
  • ,
  • Ayumu Kodama
  • ,
  • Rika Unesaki
  • ,
  • Nanako Doi
  • ,
  • Toshio Suzuki
  • ,
  • Kazuya Koumoto

49
10
開始ページ
1150
終了ページ
1153
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1246/cl.200366
出版者・発行元
CHEMICAL SOC JAPAN

We prepared renatured beta-1,3-1,6-glucan nanoparticles from molecular-weight-fractionated beta-1,3-1,6-glucans to analyze the molecular effects on the inclusion and release of the guest molecule curcumin. Glucan molecular weight strongly affects the amount of curcumin included in the complexes and its release rate. We found that the slow release rate of the incorporated curcumin is attributed not only to the stabilized stacking structure but also the slow migration between the internal and surface cavities characteristic of polymeric materials.


リンク情報
DOI
https://doi.org/10.1246/cl.200366
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000568846700008&DestApp=WOS_CPL
ID情報
  • DOI : 10.1246/cl.200366
  • ISSN : 0366-7022
  • eISSN : 1348-0715
  • Web of Science ID : WOS:000568846700008

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