2021年1月15日
Synthetic Access to gem-Difluoropropargyl Vinyl Ethers and Their Application to Propargyl Claisen Rearrangement
The Journal of Organic Chemistry
ダウンロード
回数 : 34
- ,
- ,
- ,
- ,
- ,
- ,
- 巻
- 86
- 号
- 2
- 開始ページ
- 1911
- 終了ページ
- 1924
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1021/acs.joc.0c01777
- 出版者・発行元
- American Chemical Society ({ACS})
With the increasing importance of fluorine to medicinal chemistry and other areas, methods to access various fluorinated compounds are needed. Herein, we report the synthesis of difluoropropargyl vinyl ethers from ketones and aldehydes using difluoropropargyl bromide dicobalt complexes. We applied difluoropropargyl vinyl ethers to the synthesis of difluorodienone or difluoroallene under thermal conditions and trifluoro-pyran under acid-catalyzed conditions.
- ID情報
-
- DOI : 10.1021/acs.joc.0c01777
- ORCIDのPut Code : 84953804
- PubMed ID : 33284629