Kazuyo Kamitori

Profile Information

Affiliation: Faculty of Medicine, Kagawa University

Degree: 博士（医学）(東邦大学医学部)

J-GLOBAL ID: 200901057860179334
researchmap Member ID: 6000002305

Research Interests

Research Areas

Research History

Apr, 2007 - Present

Faculty of Medicine, Kagawa University
2005 - 2007

研究員, かがわ産業支援財団
1997 - 2004

研究員, 国立精神・神経センター神経研究所
1994 - 1997

研究員, ベッセルリサーチラボラトリー
1989 - 1991

研究員, 協和発酵工業

Education

Sep, 1991 - May, 1994

大学院 (Master in Biochemistry), カンサス大学
Apr, 1985 - Mar, 1989

School of Engineering, Osaka University

Committee Memberships

2012 - Present

評議員, 日本生理学会

Awards

Dec, 2019

Rare Sugar Congress 2019優秀ポスター賞

神鳥和代
Nov, 2008

優秀ポスター賞, 第4回国際希少糖学会

神鳥和代

Papers

Structural Basis of the Selective Sugar Transport in Sodium-Glucose Cotransporters

Kazuyo Kamitori, Matsuyuki Shirota, Yuichiro Fujiwara

Journal of Molecular Biology, 434(5) 167464-167464, Mar, 2022 Peer-reviewed
D-Tagatose Effectively Reduces the Number of Streptococcus mutans and Oral Bacteria in Healthy Adult Subjects: A Chewing Gum Pilot Study and Randomized Clinical Trial.

Yuichi Nagamine, Khaleque Hasibul, Takaaki Ogawa, Ayano Tada, Kazuyo Kamitori, Akram Hossain, Fuminori Yamaguchi, Masaaki Tokuda, Tomomi Kuwahara, Minoru Miyake

Acta medica Okayama, 74(4) 307-317, Aug, 2020 Peer-reviewed
Monopolar spindle induced by isoamericanol A suppresses human breast cancer cell (MCF-7) growth

Katagi, A, Sui, L, Kamitori, K, Suzuki, T, Katayama, T, Dong, Y, Nakagawa, T, Yube, K, Hossain, A, Yamaguchi, F, Tokuda, M

Asian Journal of Cell Biology, 14(1) 1-6, Jan, 2019 Peer-reviewed
Both Ser361 phosphorylation and the C-arrestin domain of thioredoxin interacting protein are important for cell cycle blockade at the G1/S checkpoint.

Kazuyo Kamitori, Fuminori Yamaguchi, Youyi Dong, Akram Hossain, Ayako Katagi, Chisato Noguchi, Yuko Hirata, Ikuko Tsukamoto, Naoya Hatano, Masaaki Tokuda

FEBS open bio, 8(11) 1804-1819, Nov, 2018 Peer-reviewed
PPARγ activation mitigates glucocorticoid receptor-induced excessive lipolysis in adipocytes via homeostatic crosstalk.

Arif U Hasan, Koji Ohmori, Takeshi Hashimoto, Kazuyo Kamitori, Fuminori Yamaguchi, Asadur Rahman, Masaaki Tokuda, Hiroyuki Kobori

Journal of cellular biochemistry, 119(6) 4627-4635, Jun, 2018 Peer-reviewed
Additive antitumour effect of D‑allose in combination with cisplatin in non-small cell lung cancer cells.

Nobuhiro Kanaji, Kazuyo Kamitori, Akram Hossain, Chisato Noguchi, Ayako Katagi, Norimitsu Kadowaki, Masaaki Tokuda

Oncology reports, 39(3) 1292-1298, Mar, 2018 Peer-reviewed
Combined treatment with D-allose, docetaxel and radiation inhibits the tumor growth in an in vivo model of head and neck cancer.

Hiroshi Hoshikawa, Kazuyo Kamitori, Kanako Indo, Terushige Mori, Mizuna Kamata, Tomoko Takahashi, Masaaki Tokuda

Oncology letters, 15(3) 3422-3428, Mar, 2018 Peer-reviewed
The role of calcitonin gene-related peptide in migraine prevention by botulinum toxin type A.

Pleumsamran J, Pleumsamran J, Grand SM, Chankrachang S, Yamaguchi F, Kamitori K, Hossain A, Noguchi C, Sui L, Katagi A, Dong Y, Tokuda M

Neurology Asia, 23(1) 45-53, Mar, 2018 Peer-reviewed
Effects of a rare sugar, D-allulose, coingested with fat on postprandial glycemia and lipidemia in young women.

Kuzawa K, Sui L, Hossain A, Kamitori K, Tsukamoto I, Yoshida A, Tokuda M, Naito M

Journal of Nutrition and Human Health, 03(01), 2018
GPR120 in adipocytes has differential roles in the production of pro-inflammatory adipocytokines

Arif Ul Hasan, Koji Ohmori, Takeshi Hashimoto, Kazuyo Kamitori, Fuminori Yamaguchi, Takahisa Noma, Junsuke Igarashi, Kazuhito Tsuboi, Masaaki Tokuda, Akira Nishiyama, Masakazu Kohno

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 486(1) 76-82, Apr, 2017 Peer-reviewed
D-Allose Inhibits Cancer Cell Growth by Reducing GLUT1 Expression

Chisato Noguchi, Kazuyo Kamitori, Akram Hossain, Hiroshi Hoshikawa, Ayako Katagi, Youyi Dong, Li Sui, Masaaki Tokuda, Fuminori Yamaguchi

TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE, 238(2) 131-141, Feb, 2016 Peer-reviewed
Inhibitory effect of isoamericanol A from Jatropha curcas seeds on the growth of MCF-7 human breast cancer cell line by G2/M cell cycle arrest.

Ayako Katagi, Li Sui, Kazuyo Kamitori, Toshisada Suzuki, Takeshi Katayama, Akram Hossain, Chisato Noguchi, Youyi Dong, Fuminori Yamaguchi, Masaaki Tokuda

Heliyon, 2(1) e00055, Jan, 2016 Peer-reviewed
Eicosapentaenoic acid upregulates VEGF-A through both GPR120 and PPAR gamma mediated pathways in 3T3-L1 adipocytes

Arif U. Hasan, Koji Ohmori, Kumi Konishi, Junsuke Igarashi, Takeshi Hashimoto, Kazuyo Kamitori, Fuminori Yamaguchi, Ikuko Tsukamoto, Toru Uyama, Yasuhiro Ishihara, Takahisa Noma, Masaaki Tokuda, Masakazu Kohno

MOLECULAR AND CELLULAR ENDOCRINOLOGY, 406(C) 10-18, May, 2015 Peer-reviewed
Rare sugar D-psicose prevents progression and development of diabetes in T2DM model Otsuka Long-Evans Tokushima Fatty rats

Akram Hossain, Fuminori Yamaguchi, Kayoko Hirose, Toru Matsunaga, Li Sui, Yuko Hirata, Chisato Noguchi, Ayako Katagi, Kazuyo Kamitori, Youyi Dong, Ikuko Tsukamoto, Masaaki Tokuda

DRUG DESIGN DEVELOPMENT AND THERAPY, 9 525-535, 2015 Peer-reviewed
Effects of D-allose in combination with docetaxel in human head and neck cancer cells

Kanako Indo, Hiroshi Hoshikawa, Kazuyo Kamitori, Fuminori Yamaguchi, Terusige Mori, Masaaki Tokuda, Nozomu Mori

INTERNATIONAL JOURNAL OF ONCOLOGY, 45(5) 2044-2050, Nov, 2014 Peer-reviewed
THE EXPRESSION OF PTEN IN THE DEVELOPMENT OF MOUSE COCHLEAR LATERAL WALL

Y. Dong, L. Sui, F. Yamaguchi, K. Kamitori, Y. Hirata, A. Hossain, C. Noguchi, A. Katagi, M. Nishio, A. Suzuki, X. Lou, M. Tokuda

NEUROSCIENCE, 258 263-269, Jan, 2014 Peer-reviewed
Valsartan ameliorates constitutive adipokine expression pattern in mature adipocytes

Arif U, Hasan, Koji Ohmori, Takeshi Hashimoto, Kazuyo Kamitori, Fuminori Yamaguchi, Yasuhiro Ishihara, Naoko Ishihara, Takahisa Noma, 徳田雅明, Masakazu Kohno

Hypertension Research, 1-37, 2013 Peer-reviewed
Role of PTEN in the development of inner ear

Dong Youyi, Li Sui, Fuminori Yamaguchi, Kazuyo Kamitori, Yuko Hirata, Ma Hossain, Akira Suzuki, Masaaki Tokuda

JOURNAL OF PHYSIOLOGICAL SCIENCES, 63 S287-S287, 2013
Rare sugar D-psicose protects pancreas beta-islets and thus improves insulin resistance in OLETF rats

Akram Hossain, Fuminori Yamaguchi, Toru Matsunaga, Yuko Hirata, Kazuyo Kamitori, Youyi Dong, Li Sui, Ikuko Tsukamoto, Masaki Ueno, Masaaki Tokuda

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 425(4) 717-723, Sep, 2012 Peer-reviewed
Rare sugar D-allose strongly induces thioredoxin-interacting protein and inhibits osteoclast differentiation in Raw264 cells

Kana Yamada, Chisato Noguchi, Kazuyo Kamitori, Youyi Dong, Yuko Hirata, Mohammad A. Hossain, Ikuko Tsukamoto, Masaaki Tokuda, Fuminori Yamaguchi

NUTRITION RESEARCH, 32(2) 116-123, Feb, 2012 Peer-reviewed

Misc.

Effect of Ingesting Rare Sugar Syrup with Fat Cream on Postprandial Glycemia and Lipidemia in Young Women

Kaori KUZAWA, Eri IKEDA, Mieko KAGAYA, Junko KAWAI, Misaki NAKAMURA, Li SUI, Akram HOSSAIN, Kazuyo KAMITORI, Ikuko TSUKAMOTO, Akihiro YOSHIDA, Masaaki TOKUDA, Michitaka NAITO

(50), 2019
希少糖の健康機能について希少糖研究最前線

徳田雅明, 神鳥和代, ホセイン・アクラム

生物試料分析, 42(1) 25-25, Jan, 2019
希少糖D-タガトースとD-プシコースの口腔内細菌に対する増殖抑制効果

永峰優一, 小川尊明, 三宅実, 神鳥和代, 山口文徳, 徳田雅明

日本生理学雑誌, 80(3) 39-39, Aug, 2018
香川発「希少糖」の健康機能と食品・医薬品への応用可能性について

徳田雅明, 山口文徳, ホセイン・アクラム, 神鳥和代

New Diet Therapy, 33(2) 82-82, Sep, 2017
希少糖D-アロースにより活性化されるシグナル伝達系の解析とそれを用いた新規癌治療法開発の可能性

神鳥和代, 山口文徳, 董有毅, ホセイン・アクラム, 隋麗, 片木絢子, 野口知里, 星川広史, 徳田雅明

日本生理学雑誌, 79(1) 45-46, Feb, 2017
広がる「夢の糖」希少糖の世界産学官連携によるアカデミア発シーズを用いた実用化への道夢の糖「希少糖」の魅力

徳田雅明, 山口文徳, 神鳥和代, 飯田哲朗

日本薬学会年会要旨集, 136年会(1) 124-124, Mar, 2016
希少糖D-アロースによるGLUT1の発現減少とそのメカニズム検討

野口知里, 山口文徳, 神鳥和代, Hossain Akram, 片木絢子, 董有毅, 徳田雅明

日本薬学会年会要旨集, 136年会(2) 214-214, Mar, 2016
ジャトロファの種からの抽出物であるイソアメリカノールAはMCF-7ヒト乳癌細胞をG2/M期で停止することで増殖抑制作用を示す

片木絢子, 隋麗, 神鳥和代, 鈴木利貞, 片山健至, アクラム・ホセイン, 野口知里, 董有毅, 山口文徳, 徳田雅明

日本生理学雑誌, 78(1) 2-3, Jan, 2016
Regulation of thioredoxin interacting protein(TXNIP) expression by p44/p42 MAPK-p90RSK pathway

Kazuyo Kamitori, Fuminori Yamaguchi, Dong Youyi, Akram Hossain, Yuko Hirata, Ayako Katagi, Chisato Noguchi, Masahiro Hisaoka, Masaaki Tokuda

JOURNAL OF PHYSIOLOGICAL SCIENCES, 63 S201-S201, 2013
Rare sugar D-allose strongly induces thioredoxin interacting protein (TXNIP) expression and inhibits osteoclast differentiation

Chisato Noguchi, Kana Yamada, Fuminori Yamaguchi, Kazuyo Kamitori, Youyi Dong, Yuko Hirata, Akram Hossein, Ikuko Tsukamoto, Masaaki Tokuda

JOURNAL OF PHYSIOLOGICAL SCIENCES, 63 S250-S250, 2013
Thioredoxin interacting protein(TXNIP)リン酸化を介した細胞周期G1/Sチェックポイントにおける制御機構(Role of thioredoxin interacting protein (TXNIP) during the G1/S checkpoint of cell cycle through its phosphorylation)

神鳥和代, 山口文徳, 董有毅, 波多野直哉, 徳田雅明

日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, 83回・33回 2P-0388, Dec, 2010
PPAR-gamma enhances adipogenesis by down-regulating a cell cycle inhibitor, p16INK4a, in adipocytes

A. Hasan, K. Ohmori, T. Hasimoto, K. Kamitori, Y. Hirata, Y. Ishihara, N. Okamoto, T. Noma, M. Tokuda, M. Kohno

EUROPEAN HEART JOURNAL, 31 539-539, Sep, 2010
The role of PTEN in the development of inner ear

Youyi Dong, Li Sui, Fuminori Yamaguchi, Kazuyo Kamitori, Yuko Hirata, Akira Suzuki, Masaaki Tokuda

JOURNAL OF PHYSIOLOGICAL SCIENCES, 60 S185-S185, 2010
Role of thioredoxin interacting protein (TXNIP) in cell cycle regulation at the G1/S check point through its phosphorylation

Kazuyo Kamitori, Fuminori Yamaguchi, Naoya Hatano, Youyi Dong, Masaaki Tokuda

JOURNAL OF PHYSIOLOGICAL SCIENCES, 60 S76-S76, 2010
Thioredoxin interacting protein(TXNIP)リン酸化を介した細胞周期G1/Sチェックポイントにおける制御機構

神鳥和代, 波多野直哉, 下村幸子, 山口文徳, 徳田雅明

日本生化学会大会プログラム・講演要旨集, 82回 4P-368, Sep, 2009
Thioredoxin interacting protein(TXNIP)の細胞周期G1/Sチェックポイントにおける役割

神鳥和代, 山口文徳, 波多野直哉, 徳田雅明

日本生理学雑誌, 71(2) 70-70, Feb, 2009
RARE SUGAR D-ALLOSE ENHANCES ANTI-TUMOR EFFECT OF 5-FLUOROURACIL ON THE HUMAN HEPATOCELLULAR CARCINOMA CELL LINE HuH-7

Fuminori Yamaguchi, Kamitori Kazuyo, Dong Youyi, Yuko Hirata, Masaaki Tokuda

JOURNAL OF PHYSIOLOGICAL SCIENCES, 59 304-304, 2009
ROLE OF THIOREDOXIN INTERACTING PROTEIN (TXNIP) IN CELL CYCLE REGULATION

Kazuyo Kamitori, Fuminori Yamaguchi, Naoya Hatano, Li Sui, Yuko Hirata, Youyi Dong, Masaaki Tokuda

JOURNAL OF PHYSIOLOGICAL SCIENCES, 59 303-303, 2009
ANALYSIS OF THE INHIBITORY EFFECT OF D-ALLOSE ON LEUKEMIA CELL PROLIFERATION

Yuko Hirata, Ikuko Tsukamoto, Fuminori Yamaguchi, Sui Li, Kazuyo Kamitori, Youyi Dong, Masaaki Tokuda

JOURNAL OF PHYSIOLOGICAL SCIENCES, 59 304-304, 2009
EFFECT OF RARE SUGARS ON RAT LIVER REGENERATION AFTER 90% RESECTION

Mohammad Akram Hossain, Fuminori Yamaguchi, Kazuyo Kamitori, Youyi Dong, Yasuyuki Suzuki, Masaaki Tokuda

JOURNAL OF PHYSIOLOGICAL SCIENCES, 59 437-437, 2009

Presentations

Transport mechanism of various sugars by sodium-glucose cotransporters (SGLTs)

Kazuyo Kamitori, Matsuyuki Shirota, Yuichiro Fujiwara

Mar 16, 2022
ナトリウム-グルコース共輸送体 SGLT における糖の選択的輸送機構

神鳥和代, 城田松之, 藤原祐一郎

第 73 回日本生理学会中国四国地方会, Nov 6, 2021
Human hexokinase3 has a high enzymatic activity to a rare sugar, D-allose

The 40th Annual Meeting of Japanese Society of Carbohydrate Research, Oct 29, 2021
Molecular basis for sugar specificity of Na+/glucose co-transporters -How are sugars taken into our bodies?-

Kazuyo Kamitori, Yuichiro Fujiwara

Mar 29, 2021
Molecular basis for hexose specificity of Na+/D-glucose co-transporters

Kazuyo Kamitori, Yuichiro Fujiwara

Sep 14, 2020
Structural and molecular basis of Na+/D-glucose co-transporters hexose specificity

Kazuyo Kamitori, Yuichiro Fujiwara

Mar 18, 2020 Invited
Sugar specificity and structural analyses of Na+/D-glucose co-transporters

KAMITORI Kazuyo

Rare Sugar Congress 2019, Dec, 2019
ナトリウム・グルコース共輸送体の糖選択性に関わる分子構造基盤解析

神鳥和代

２０１９年度生理研研究会＠大阪, Sep, 2019
Toward the understanding of hexose specificity of Na+/D-glucose cotransporters SGLT1 and SGLT2

KAMITORI Kazuyo, FUJIWARA Yuichiro

The 9th Federation of the Asian and Oceanian Physiological Societies Congress, Mar 29, 2019
D-allose induces tumor suppressive factor TXNIP (thioredoxin interacting protein) through transcriptional and translational regulation

KAMITORI Kazuyo

The 7th Joint Symposium Between Kagawa University and Chiang Mai University, Aug, 2018
希少糖D-アロースにより発現誘導される癌抑制因子Thioredoxin interacting protein (TXNIP) の解析と新規癌治療法開発の可能性

神鳥和代

第36回日本糖質学会年会, Jul, 2017
Analysis of the regulatory mechanism of D-allose-inducible tumor suppressive factor thioredoxin interacting protein (TXNIP)

KAMITORI Kazuyo

Mar, 2017
Analysis of the regulatory mechanism of D-allose-inducibletumor suppressive factor TXNIP (thioredoxin interacting protein)

KAMITORI Kazuyo

Rare Sugar Congress 2016 in Kagawa, Nov, 2016
希少糖D-アロースにより活性化されるシグナル伝達系の解析とそれを用いた新規癌治療法開発の可能性

神鳥和代, 山口文徳, 董有毅, ホセインアクラム, 隋麗, 片木絢子, 野口知里, 星川広史, 徳田雅明

第68回日本生理学会中国四国地方会, Nov, 2016
希少糖D-アロースにより活性化されるシグナル伝達系の解析とそれを用いた新規癌治療法開発の可能性

神鳥和代

第35回日本糖質学会年会, Sep, 2016 Invited
Analysis of the regulatory mechanism of D-allose-inducible

Kazuyo Kamitori

The 6th Joint Symposium between Kagawa University and Chiang Mai University, Aug, 2016
Analysis of the regulatory mechanism of D-allose-inducible tumor suppressive factor TXNIP (thioredoxin interacting protein) for development of a new cancer therapy

Kazuyo Kamitori, Fuminori Yamaguchi, Youyi Dong, Akram Hossain, Li Sui, Ayako Katagi, Chisato Noguchi, Masaaki Tokuda

Mar, 2016
希少糖D-アロースにより発現誘導される制因子Thioredoxin interacting protein(TXNIP)のin vivo での関与

第92回日本生理学会大会, 2015
Thioredoxin interacting protein (TXNIP)の癌治療法への応用に向けた制御解析

第91回日本生理学会大会, 2014
Molecular analysis of D-allose anti-proliferative effect for development of a new cancer therapy

国際希少糖学会シンポジウム2014, 2014 Invited

Teaching Experience

Jun, 2021 - Jun, 2021

Physiology of Biological Membrane (Kagawa University)
生理学実習 (香川大学)
生理学 (香川大学)

Professional Memberships

Research Projects

昆虫の甘味シグナルの解明 -昆虫は希少糖が嫌いなのか？-

研究推進事業（若手研究経費）, 香川大学, Apr, 2021 - Mar, 2022
希少糖を用いたナトリウム・グルコース共輸送体の糖透過性の分子構造基盤解析

科研費基盤研究（C), 日本学術振興会, Apr, 2019 - Mar, 2022

神鳥和代
「希少糖はなぜ甘い？」希少糖の甘味感覚シグナル伝達機構の解明

研究推進事業（シーズ開発経費）, 香川大学, Apr, 2020 - Mar, 2021
希少糖D-アロースによるTXNIP発現誘導を介した癌治療法の開発

科研費（基盤研究C), 日本学術振興会, Apr, 2016 - Mar, 2019

神鳥和代
D-アロースによる癌細胞増殖抑制作用を利用した新たな癌治療戦略の確立-

新領域・組織連携研究, 香川大学, Apr, 2012 - Mar, 2013

神鳥和代
TXNIPのリン酸化を介した細胞周期制御機構の解明

萌芽研究, 香川大学医学部, Apr, 2009 - Mar, 2010

神鳥和代
生理学、神経科学
physiology

Profile Information

Research Interests

Research Areas

Research History

Education

Committee Memberships

Awards

Papers

Misc.

Presentations

Teaching Experience

Professional Memberships

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