松山正剛 (正剛松山) - マイポータル

基本情報

所属: 姫路獨協大学薬学部医療薬学科教授

学位: 医学博士(神戸大学)

J-GLOBAL ID: 200901076722734798
researchmap会員ID: 6000002835

研究キーワード

研究分野

委員歴

日本薬理学会, 評議員

受賞

1999年

上原記念生命科学財団研究奨励金

MISC

Quantitative Analysis of beta-Amyloid Peptides Expressed in Human Cerebrospinal Fluid by an Improved Method of Antibody-Assisted Time-of-Flight Mass Spectrometry

Akira Matsumoto, Reiko Matsumoto, Kei-ichi Kadoyama, Taka-aki Nishimoto, Shogo Matsuyama, Osamu Midorikawa

INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS 15(3) 205-210 2009年9月
Inverse correlation between APP and synaptic plasticity in transgenic mice.

Shogo Matsuyama, Takami Tomiyama, Rie Teraoka, Hiroshi Mori

NeuroReport (18(10)) 1083-1087 2007年
Transgenic mice expressing mutant (N279K) human tau show mutation dependent cognitive deficits without neurofibrillary tangle formation

T Taniguchi, N Doe, S Matsuyama, Y Kitamura, H Mori, N Saito, C Tanaka

FEBS LETTERS 579(25) 5704-5712 2005年10月
Spatial learning of mice lacking a neuron-specific EGF family protein, NELL2.

Shogo Matsuyama, Nobuyuki Doe, Naoki Kurihara, Katsuyuki Tanizawa, Shun’ichi Kuroda, Hiroyuki Iso, Masato Horie

J. Pharmacol. Sci. 98(3) 239-243 2005年
Enhanced long-term potentiation in vivo in dentate gyrus of NELL2-deficient mice

S Matsuyama, K Aihara, N Nishino, S Takeda, K Tanizawa, S Kuroda, M Horie

NEUROREPORT 15(3) 417-420 2004年3月
Epibatidine induces long-term potentiation (LTP) via activation of α4β2 nicotinic acetylcholine receptors (nAChRs) in vivo in the intact mouse dentate gyrus: Both α7 and α4β2 nAChRs essential to nicotinic LTP

Shogo Matsuyama, Akira Matsumoto

Journal of Pharmacological Sciences 93(2) 180-187 2003年10月
A neuron-specific EGF family protein, NELL2, promotes survival of neurons through mitogen-activated protein kinases

K Aihara, S Kuroda, N Kanayama, S Matsuyama, K Tanizawa, M Horie

MOLECULAR BRAIN RESEARCH 116(1-2) 86-93 2003年8月
Impaired long-term potentiation in vivo in the dentate gyrus of pituitary adenylate cyclase-activating polypeptide (PACAP)- or PACAP type 1 receptor-mutant mice.

Shogo Matsuyama, Akira Matsumoto, Hitoshi Hashimoto, Norihito Shintani, Akemichi Baba

NeuroReport 14(14) 2095-2098 2003年
Expression and distribution of carboxypeptidase B in the hippocampal subregions of normal and Alzheimer's disease brain

H Papp, Torok, I, A Matsumoto, T Enomoto, S Matsuyama, P Kasa

ACTA BIOLOGICA HUNGARICA 54(1) 55-62 2003年
Brain-specific carboxypeptidase B: Selective down-regulation in ependymal cell by irradiation and altered beta-amyloid processing

T Kawabe, R Sasaki, H Nishimura, T Soejima, S Matsuyama, K Sugimura, A Matsumoto

NEUROSCIENCE RESEARCH COMMUNICATIONS 31(2) 75-84 2002年9月
Critical role of presynaptic nicotinic ACh receptor in the formation of long-term potentiation: implications for development of anti-dementia drugs.

Tomoyuki Nishizaki, Tamotsu Nomura, Shogo Matsuyama, Takeshi Kondoh, Etsuko, Fujimoto, Mitsunobu Yoshii

Psychogeriatrics 1(1) 209-217 2001年
Human brain carboxypeptidase B, which cleaves beta-amyloid peptides in vitro, is expressed in the endoplasmic reticulum of neurons.

Akira Matsumoto, Kyoko Itoh, Tsuneyoshi Seki, Kenjiro Motozaki, Shogo Matsuyama

Eur. J. Neurosci. 13(13) 1653-1657 2001年
Mice with markedly reduced PACAP (PAC(1)) receptor expression by targeted deletion of the signal peptide

H Hashimoto, N Shintani, A Nishino, M Okabe, M Ikawa, S Matsuyama, K Itoh, K Yamamoto, S Tomimoto, T Fujita …

JOURNAL OF NEUROCHEMISTRY 75(5) 1810-1817 2000年11月
Sustained facilitatory action of FK960 on hippocampal neurotransmission

S Matsuyama, T Nomura, T Nishizaki

BRAIN RESEARCH 857(1-2) 317-320 2000年2月
Activation of nicotinic acetylcholine receptors induces long-term potentiation in vivo in the intact mouse dentate gyrus.

Shogo Matsuyama, Akira Matsumoto, Taira Enomoto, Tomoyuki Nishizaki

Eur. J. Neurosci. 12(12) 3741-3747 2000年
An “LTP-like” facilitation of hippocampal synaptic transmission induced by the nootropic nefiracetam.

Tomoyuki Nishizaki, Toshiyuki Matsuoka, Tamotsu Nomura, Shogo Matsuyama, Shigeo Watabe, Tadashi Shiotani, Mitsunobu Yoshii

Brain Res. 826(2) 281-288 1999年
Long-term potentiation persistence greater in C57BL/6 than DBA/2 mice: predicted on basis of protein kinase C levels and learning performance

S Matsuyama, U Namgung, A Routtenberg

BRAIN RESEARCH 763(1) 127-130 1997年7月
Regulation of GABA release via NMDA and 5-HT1A receptors in guinea pig dentate gyrus

S Matsuyama, K Nei, C Tanaka

BRAIN RESEARCH 761(1) 105-112 1997年6月
Long-term potentiation activates the GAP-43 promoter: selective participation of hippocampal mossy cells.

Uk Namgung, Shogo Matsuyama, Aryeh Routtenberg

Proc. Natl. Acad. Sci. USA 94(21) 11675-11680 1997年
Regulation of glutamate release via NMDA and 5-HT1A receptors in guinea pig dentate gyrus

S Matsuyama, K Nei, C Tanaka

BRAIN RESEARCH 728(2) 175-180 1996年7月

もっとみる

書籍等出版物

Mice with markedly reduced PACAP(PAC1)receptor expression by targeted deletion of the signal peptide (共著）

J.Neurochem.

所属学協会

Works(作品等)

Joint Research on Effects on Long-Term Potentiation of Nootropic drugs

1997年 - 2000年
抗痴呆薬の長期増強現象への作用の共同研究

1997年 - 2000年
Joint Research on Roles of Nicotinic ACh Receptors on Long-Term Potentiation

1998年
長期増強現象におけるニコチン受容体の役割の共同研究

1998年
Joint Research on Function of PACAP

1997年
ＰＡＣＡＰの機能に関する共同研究

1997年

共同研究・競争的資金等の研究課題

長期増強現象における遺伝子発現と蛋白合成

脳科学研究 2007年 - 2012年
長期増強現象における遺伝子発現と蛋白合成

The Other Research Programs
長期増強の機構に関する研究
海馬長期増強現象に関する研究

補助金
Study on in vivo Long-Term Potentiation in hippocampus
抗痴呆薬の開発に関する研究
Research on Development of Nootropic drugs
Research on Mechanism of Long-Term Potentiation