2015年3月1日
Evaluation of the relationship between T1ρ and T2 values and patella cartilage degeneration in patients of the same age group
European Journal of Radiology
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- 巻
- 84
- 号
- 3
- 開始ページ
- 463
- 終了ページ
- 468
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1016/j.ejrad.2014.11.015
- 出版者・発行元
- Elsevier Ireland Ltd
Objective The aim of this study was to investigate the association between the T1ρ and T2 values and the progression of cartilage degeneration in patients of the same age group. Materials and methods Sagittal T1ρ and T2 mapping and three-dimensional (3D) gradient-echo images were obtained from 78 subjects with medial knee osteoarthritis (OA). The degree of patella cartilage degeneration was classified into four groups using MRI-based grading: apparently normal cartilage, mild OA, moderate OA, and severe OA group. We measured the T1ρ and T2 values (ms) in the regions of interest set on the full-thickness patella cartilage. Then, we analyzed the relationship between the T1ρ and T2 values and the degree of patella cartilage degeneration. Results There were no significant differences in age among the four groups. Both the T1ρ and T2 values showed a positive correlation with the degree of OA progression (ρ = 0.737 and ρ = 0.632, respectively). By comparison between the apparently normal cartilage and the mild OA groups, there were significant differences in the T1ρ mapping, but not in the T2 mapping. Conclusions Our study confirmed that T1ρ and T2 mapping can quantitatively evaluate the degree of patella cartilage degeneration in patients within the same age group.
- リンク情報
- ID情報
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- DOI : 10.1016/j.ejrad.2014.11.015
- ISSN : 1872-7727
- ISSN : 0720-048X
- PubMed ID : 25559169
- SCOPUS ID : 84923264554