Nishimura Ken

J-GLOBAL         Last updated: Jan 16, 2020 at 02:49
 
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Name
Nishimura Ken
E-mail
ken-nishimuramd.tsukuba.ac.jp
Affiliation
University of Tsukuba
Section
Faculty of Medicine
Job title
Associate Professor
Research funding number
80500610

Research Areas

 
 

Published Papers

 
Fukuda, Aya; Honda, Shiho; Fujioka, Norie; Sekiguchi, Yuya; Mizuno, Seiya; Miwa, Yoshihiro; Sugiyama, Fumihiro; Hayashi, Yohei; Nishimura, Ken; Hisatake, Koji
PloS one   14(11)    Apr 2019
Uncoupling protein 1 (UCP1) is a mitochondrial protein that is expressed in both brown and beige adipocytes. UCP1 uncouples the mitochondrial electron transport chain from ATP synthesis to produce heat via non-shivering thermogenesis. Due to their...
Bui, Phuong Linh; Nishimura, Ken; Seminario Mondejar, Gonzalo; Kumar, Arun; Aizawa, Shiho; Murano, Kensaku; Nagata, Kyosuke; Hayashi, Yohei; Fukuda, Aya; Onuma, Yasuko; Ito, Yuzuru; Nakanishi, Mahito; Hisatake, Koji
Cell reports   29(7) 1909-1922.e5   Nov 2019
Reprogramming somatic cells to induced pluripotent stem cells (iPSCs) is accompanied by dramatic changes in epigenetic programs, including silencing of endogenous and exogenous retroviruses. Here, we utilized replication-defective and persistent S...
Nishimura, Ken; Fukuda, Aya; Hisatake, Koji
International Journal of Molecular Sciences   20(9)    May 2019
Pluripotent stem cells (PSCs), including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), hold a huge promise for regenerative medicine, drug development, and disease modeling. PSCs have unique metabolic features that are ak...
Nishimura, Ken;Ishiwata, Hiroshi;Sakuragi, Yuta;Hayashi, Yohei;Fukuda, Aya;Hisatake, Koji
Scientific Reports   9 1777   Feb 2019   [Refereed]
Pluripotent stem cells (PSCs) have various degrees of pluripotency, which necessitates selection of PSCs with high pluripotency before their application to regenerative medicine. However, the quality control processes for PSCs are costly and time-...
Tsukamoto, Masaya; Nishimura, Toshiya; Yodoe, Kyohei; Kanegi, Ryoji; Tsujimoto, Yasunori; Alam, Md Emtiaj; Kuramochi, Mizuki; Kuwamura, Mitsuru; Ohtaka, Manami; Nishimura, Ken; Nakanishi, Mahito; Inaba, Toshio; Sugiura, Kikuya; Hatoya, Shingo
Stem cells and development   27(22)    Sep 2018   [Refereed]
Canine induced pluripotent stem cells (ciPSCs) can be used in regenerative medicine. However, there are no reports on the generation of genome integration free and completely exogeneous gene silenced (footprint-free) ciPSCs that are tolerant to en...

Conference Activities & Talks

 
非線形光学イメージングを用いた iPS 細胞のリプログラミング過程の研究
加納, 英明;丸山拓史;米山弘亮;西村健;久武幸司
平成30年度 日本分光学会年次講演会   22 May 2018   
Analysis on transcriptional regulation in the early phase of somatic cell reprogramming
FUKUDA, AYA;Anh, Le Phuong Hoang;Tetsuo, Kato;TL, Nguyen;Ken, Nishimura;Koji, Hisatake
Tsukuba Global Science Week 2018   Sep 2018   
Functional analysis of unsaturated fatty acids in brown adipocytes
FUKUDA, AYA;Rie, Hirai;Yuki, Takei;Y, Shimodaira;Hideaki, Kano;Rintaro, Shimada;Ken, Nishimura;Koji, Hisatake
Tsukuba Global Science Week 2018   Sep 2018   
Functional analysis of SOX9 variants in chondrocyte differentiation
FUKUDA, AYA;Sekiguchi, Yuya;Ken, Nishimura;Koji, Hisatake
Tsukuba Global Science Week 2018   Sep 2018   
褐色脂肪細胞における不飽和脂肪酸の機能解析
福田, 綾;平井理愛;武井祐樹;下平雄貴;加納英明;島田林太郎;西村健;久武幸司
第41回日本分子生物学会年会   Nov 2018