2015年4月
Cortisol level measurements in fingernails as a retrospective index of hormone production
PSYCHONEUROENDOCRINOLOGY
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- 巻
- 54
- 号
- 開始ページ
- 24
- 終了ページ
- 30
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1016/j.psyneuen.2015.01.015
- 出版者・発行元
- PERGAMON-ELSEVIER SCIENCE LTD
The cortisol Level in fingernails may reflect the hormone's cumulative production over a long period, but the notions have not been fully established. In this study, we investigated the association of cortisol in fingernails with cortisol accumulation over a long period (hair cortisol) and over a relatively short period (salivary cortisol). In study 1, hair and fingernail samples were collected from 58 middle-aged and elderly men. The cortisol level in hair samples was moderately associated with the level in fingernail samples (r=0.29, p < 0.05 and r(5)=0.36, p < 0.01). In study 2, 37 workers provided 4 saliva samples over the course of one day (at awakening, 30 min after awakening, before lunch, and after work) and another set a month later. Further, the workers were asked to provide fingernail samples during a six-month period. We found that the cortisol level in saliva over the whole day (area under the curve for cortisol) was moderately associated with the cortisol level measured in fingernail samples that were collected 4 months (r=0.43, p < 0.05 and r(s)=0.50, p < 0.01) and 5 months later (r=0.45, p < 0.05 and r(s)=0.53, p < 0.01). These results indicated that the cortisol level in fingernail samples might retrospectively represent hormone production during a given period. The cortisol level in fingernail samples may be useful in the investigation of the link between psychosocial stress and health. (C) 2015 Elsevier Ltd. All rights reserved.
- リンク情報
- ID情報
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- DOI : 10.1016/j.psyneuen.2015.01.015
- ISSN : 0306-4530
- PubMed ID : 25662340
- Web of Science ID : WOS:000352748000003