論文

査読有り
2015年4月

Cortisol level measurements in fingernails as a retrospective index of hormone production

PSYCHONEUROENDOCRINOLOGY
  • Shuhei Izawa
  • ,
  • Keiichi Miki
  • ,
  • Masao Tsuchiya
  • ,
  • Takeshi Mitani
  • ,
  • Toru Midorikawa
  • ,
  • Tatsuya Fuchu
  • ,
  • Taiki Komatsu
  • ,
  • Fumiharu Togo

54
開始ページ
24
終了ページ
30
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1016/j.psyneuen.2015.01.015
出版者・発行元
PERGAMON-ELSEVIER SCIENCE LTD

The cortisol Level in fingernails may reflect the hormone's cumulative production over a long period, but the notions have not been fully established. In this study, we investigated the association of cortisol in fingernails with cortisol accumulation over a long period (hair cortisol) and over a relatively short period (salivary cortisol). In study 1, hair and fingernail samples were collected from 58 middle-aged and elderly men. The cortisol level in hair samples was moderately associated with the level in fingernail samples (r=0.29, p < 0.05 and r(5)=0.36, p < 0.01). In study 2, 37 workers provided 4 saliva samples over the course of one day (at awakening, 30 min after awakening, before lunch, and after work) and another set a month later. Further, the workers were asked to provide fingernail samples during a six-month period. We found that the cortisol level in saliva over the whole day (area under the curve for cortisol) was moderately associated with the cortisol level measured in fingernail samples that were collected 4 months (r=0.43, p < 0.05 and r(s)=0.50, p < 0.01) and 5 months later (r=0.45, p < 0.05 and r(s)=0.53, p < 0.01). These results indicated that the cortisol level in fingernail samples might retrospectively represent hormone production during a given period. The cortisol level in fingernail samples may be useful in the investigation of the link between psychosocial stress and health. (C) 2015 Elsevier Ltd. All rights reserved.

Web of Science ® 被引用回数 : 30

リンク情報
DOI
https://doi.org/10.1016/j.psyneuen.2015.01.015
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/25662340
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000352748000003&DestApp=WOS_CPL

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