Morito Endo

Profile Information

Affiliation: Faculty of Health Science, Hachinohe Gakuin University

Degree: 博士（医学）

J-GLOBAL ID: 200901010687809010
researchmap Member ID: 6000007819

Research Interests

Research Areas

Life sciences / Nephrology /

Research History

2006

- 日本大学医学部腎臓内分泌内科客員教授
2002 - 2005

さわらび会福祉村病院長寿医学研究所研究員
2005

- 八戸大学人間健康学部（現八戸学院大学健康医療学部）教授
1985 - 2002

Itabashi Hospital (School of Medicine), Nihon University
1993 - 1995

米国ユタ大学医学部血液腫瘍学博士研究員

Education

- 1985

School of Medicine, Hirosaki University

Committee Memberships

評議員, 日本腎臓学会

Papers

Implantation of dedifferentiated fat cells ameliorated antineutrophil cytoplasmic antibody glomerulonephritis by immunosuppression and increases in tumor necrosis factor-stimulated gene-6.

Kei Utsunomiya, Takashi Maruyama, Satoshi Shimizu, Taro Matsumoto, Morito Endo, Hiroki Kobayashi, Koichiro Kano, Masanori Abe, Noboru Fukuda

Stem cell research & therapy, 13(1) 319-319, Jul 16, 2022
Transcriptional Suppression of Diabetic Nephropathy with Novel Gene Silencer Pyrrole-Imidazole Polyamides Preventing USF1 Binding to the TGF-β1 Promoter.

Makiyo Okamura, Noboru Fukuda, Shu Horikoshi, Hiroki Kobayashi, Akiko Tsunemi, Yurie Akiya, Morito Endo, Taro Matsumoto, Masanori Abe

International journal of molecular sciences, 22(9), Apr 29, 2021
Involvement of complement 3 in the salt-sensitive hypertension by activation of renal renin-angiotensin system in spontaneously hypertensive rats.

Eriko Negishi, Noboru Fukuda, Tomoyasu Otsuki, Mayumi Katakawa, Kazutoshi Komatsu, Lan Chen, Sho Tanaka, Hiroki Kobayashi, Yoshinari Hatanaka, Takahiro Ueno …

American journal of physiology. Renal physiology, 315(6) F1747-F1758-F1758, Dec 1, 2018 Peer-reviewed
Effects of a spleen tyrosine kinase inhibitor on progression of the lupus nephritis in mice

Maki Kitai, Noboru Fukuda, Takahiro Ueno, Morito Endo, Takashi Maruyama, Masanori Abe, Kazuyoshi Okada, Masayoshi Soma, Koichi Matsumoto

JOURNAL OF PHARMACOLOGICAL SCIENCES, 134(1) 29-36, May, 2017 Peer-reviewed
HCaRG/COMMD5 inhibits ErbB receptor-driven renal cell carcinoma

Hiroyuki Matsuda, Carole G. Campion, Kyoko Fujiwara, Jin Ikeda, Suzanne Cossette, Thomas Verissimo, Maiko Ogasawara, Louis Gaboury, Kosuke Saito, Kenya Yamaguchi …

Oncotarget, 8(41) 69559-69576, 2017 Peer-reviewed
Systematic implantation of dedifferentiated fat cells ameliorated monoclonal antibody 1-22-3-induced glomerulonephritis by immunosuppression with increases in TNF-stimulated gene 6

Takashi Maruyama, Noboru Fukuda, Taro Matsumoto, Koichiro Kano, Morito Endo, Minako Kazama, Tomohiko Kazama, Jin Ikeda, Hiroyuki Matsuda, Takahiro Ueno …

STEM CELL RESEARCH & THERAPY, 6, Apr, 2015 Peer-reviewed
Role of complement 3a in the growth of mesangial cells from stroke-prone spontaneously hypertensive rats

Kazuya Ikeda, Noboru Fukuda, Takahiro Ueno, Morito Endo, Naohiko Kobayashi, Masayoshi Soma, Koichi Matsumoto

CLINICAL AND EXPERIMENTAL HYPERTENSION, 36(1) 58-63, 2014 Peer-reviewed
Complement 3 activates the renal renin-angiotensin system by induction of epithelial-to-mesenchymal transition of the nephrotubulus in mice

Xueli Zhou, Noboru Fukuda, Hiroyuki Matsuda, Morito Endo, Xiaofei Wang, Kosuke Saito, Takahiro Ueno, Taro Matsumoto, Koichi Matsumoto, Masayoshi Soma …

American Journal of Physiology - Renal Physiology, 305(7) F957-F967, Oct 1, 2013 Peer-reviewed
Complement 3 activates the renal renin-angiotensin system by induction of epithelial-to-mesenchymal transition of the nephrotubulus in mice

Xueli Zhou, Noboru Fukuda, Hiroyuki Matsuda, Morito Endo, Xiaofei Wang, Kosuke Saito, Takahiro Ueno, Taro Matsumoto, Koichi Matsumoto, Masayoshi Soma …

AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 305(7) F957-F967, Oct, 2013 Peer-reviewed
Role of Complement 3a in the Synthetic Phenotype and Angiotensin II-Production in Vascular Smooth Muscle Cells From Spontaneously Hypertensive Rats

Ying Han, Noboru Fukuda, Takahiro Ueno, Morito Endo, Kazuya Ikeda, Zhou Xueli, Taro Matsumoto, Masayoshi Soma, Koichi Matsumoto

AMERICAN JOURNAL OF HYPERTENSION, 25(3) 284-289, Mar, 2012 Peer-reviewed
Evaluation of urinary factor H excretion in patients with idiopathic membranous nephropathy

Morito Endo, Yoshinobu Fuke, Hiroyuki Ohi, Atsushi Satomura, Noboru Fukuda, Takayuki Fujita, Koichi Matsumoto

Japanese Journal of Nephrology, 49(5) 499-504, 2007 Peer-reviewed
高血圧症性腎傷害でのTGF-bの発現とDNA-RNAキメラ型リボザイムによる遺伝子治療

田平佳子, 福田昇, 遠藤守人, 鈴木亮, 池田友紀博, 高木浩人, 上松瀬勝男

血管, 25 47-51, Mar, 2002

Misc.

114

C3腎症の概念とその病態

遠藤守人, 大澤勲

八戸学院大学紀要, (49) 37-45, Dec, 2014
慢性腎臓病に対する新たな治療戦略

遠藤守人, 松本紘一, 福田昇, 丸山高史, 北井真貴, 上野高浩, 松本太郎

八戸大学紀要, (45) 79-87, Dec 27, 2012
The role of complement activation, detected by urinary C5b-9 and urinary factor H, in the excretion of urinary albumin in cisplatin nephropathy

Y. Fuke, T. Fujita, A. Satomura, M. Endo, K. Matsumoto

CLINICAL NEPHROLOGY, 71(2) 110-117, Feb, 2009
Complement 3 activates the KLF5 gene in rat vascular smooth muscle cells

En-Hui Yao, Noboru Fukuda, Takahiro Ueno, Akiko Tsunemi, Morito Endo, Koichi Matsumoto

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 367(2) 468-473, Mar, 2008
Implantation of Dedifferentiated Fat Cells Ameliorates Habu Snake Venom-Induced Chronic Renal Dysfunction in Tenascin-C-Deficient Mice

Renaguli Nur, Noboru Fukuda, Taro Matsumoto, Jumabay Medet, Koichiro Kano, Chii Yamamoto, Takashi Maruyama, Morito Endo, Koichi Matsumoto

NEPHRON EXPERIMENTAL NEPHROLOGY, 110(3) E91-E98, 2008
Complement 3 is involved in changing the phenotype of human glomerular mesangial cells

Jian-Xin Wan, Noboru Fukuda, Morito Endo, Yoshiko Tahira, En-Hui Yao, Hiroyuki Matsuda, Takahiro Ueno, Koichi Matsumoto

JOURNAL OF CELLULAR PHYSIOLOGY, 213(2) 495-501, Nov, 2007
Chimeric DNA-RNA hammerhead ribozyme targeting transforming growth factor-beta 1 mRNA ameliorates renal injury in hypertensive rats

Yoshiko Tahira, Noboru Fukuda, Morito Endo, Takahiro Ueno, Hiroyuki Matsuda, Satoshi Saito, Koichi Matsumoto, Hideo Mugishima

JOURNAL OF HYPERTENSION, 25(3) 671-678, Mar, 2007
補体制御因子と腎疾患.

八戸大学紀要, 34 1, 2007
Evaluation of urinary factor H excretion in patients with idiopathic membranous nephropathy

ENDO Morito, FUKE Yoshinobu, OHI Hiroyuki, SATOMURA Atsushi, FUKUDA Noboru, FUJITA Takayuki, MATSUMOTO Koichi

Jpn J Nephrol, 49(5) 499-504, 2007
マンノース結合レクチン（MBL）と疾患.

八戸大学紀要, 32 13, 2006
Serum mannose-binding lectin levels in maintenance hemodialysis patients: Impact on all-cause mortality

A Satomura, M Endo, T Fujita, H Ohi, Ohsawa, I, Y Fuke, K Matsumoto, S Sudo, M Matsushita, T Fujita

NEPHRON CLINICAL PRACTICE, 102(3-4) C93-C99, 2006
補体C3は転写因子KLF-5を介して腎メサンギウム細胞の形質を合成型に変換し増殖を刺激する．

第42回補体シンポジウム講演集, 42 38, 2005
Worsening fluid retention in a patient with hereditary angioedema and end-stage renal disease

Ohsawa, I, A Satomura, Y Fuke, M Hidaka, M Endo, T Fujita, H Ohi

INTERNAL MEDICINE, 43(8) 708-712, Aug, 2004
Complement 3 is involved in the synthetic phenotype and exaggerated growth of vascular smooth muscle cells from spontaneously hypertensive rats

ZH Lin, N Fukuda, XQ Jin, EH Yao, T Ueno, M Endo, S Saito, K Matsumoto, H Mugishima

HYPERTENSION, 44(1) 42-47, Jul, 2004
Variability in quantitative measurement of the same segment with two different intravascular ultrasound systems: In vivo and in vitro studies

YX Li, J Honye, S Saito, T Takayama, SI Yokoyama, T Saruya, M Kotani, K Harasawa, H Ando, M Endo …

CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS, 62(2) 175-180, Jun, 2004
Glomerular deposition and urinary excretion of complement factor H in idiopathic membranous nephropathy

M Endo, Y Fuke, M Tamano, M Hidaka, Ohsawa, I, T Fujita, H Ohi

NEPHRON CLINICAL PRACTICE, 97(4) C147-C153, 2004
Autoimmune hemolytic anemia occurred prior to evident nephropathy in a patient with chronic hepatitis C virus infection: Case report

Isao Ohsawa, Yuki Uehara, Sumiko Hashimoto, Morito Endo, Takayuki Fujita, Hiroyuki Ohi

BMC Nephrology, 4 1-7, Aug 29, 2003
血液透析患者における血清mannose-binding lectin値と生命予後の検討

里村厚司, 藤田宜是, 遠藤守人, 日高睦子, 大澤勲, 大井洋之, 松本紘一, 上松瀬勝男, 須藤祐正

日本腎臓学会誌, 45(3) 220-220, Apr, 2003
Transforming growth factor-beta expression in cardiovascular organs in stroke-prone spontaneously hypertensive rats with the development of hypertension

Y Tahira, N Fukuda, M Endo, R Suzuki, Y Ikeda, H Takagi, K Matsumoto, K Kanmatsuse

HYPERTENSION RESEARCH, 25(6) 911-918, Nov, 2002
Nephrotic syndrome with portal, splenic and renal vein thrombosis - A case report

Y Etoh, Ohsawa, I, T Fujita, Y Fuke, M Endo, H Ohi, K Kumasaka

NEPHRON, 92(3) 680-684, Sep, 2002

Books and Other Publications

抗刷子縁抗体，広範囲血液・尿検査・免疫学的検査（3）［第6版］

日本臨牀社, 2005
B因子・D因子，広範囲血液・尿検査・免疫学的検査（3）［第6版］

日本臨牀社, 2005
臨床からみた補体活性，補体学への招待

補体研究会, 2002
ネフローゼ症候群，EBM に基づく臨床データブック

中外医学社, 2001
分葉性糸球体腎炎，領域別症候群シリーズ No.16〜腎臓症候群：上巻

日本臨牀社, 1997
糸球体疾患腎炎と補体，Annual Review 腎臓

中外医学社, 1991
抗糸球体基底膜抗体，広範囲血液・尿化学検査・免疫学的検査：下巻

日本臨牀社, 1990
抗糸球体基底膜抗体と抗刷子縁抗体，臓器特異性抗体の検査法とその意義

医歯薬出版, 1990
補体産生細胞と補体の turnover，臨床免疫：上巻

日本臨牀社, 1990

Professional Memberships

Research Projects

HCaRG/COMMD5 inhibits ErbB receptor-driven clear-cell renal cell carcinoma

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Oct, 2015 - Mar, 2018

MATSUDA Hiroyuki, YAMAGUCHI Kenya, MATSUMOTO Taro, ENDO Morito, KATAKAWA Mayumi, IKEDA Jin, TREMBLAY Johanne
地域社会における予防医学の推進
糸球体腎炎における補体系に関する検討
腎障害の進展機序の解明と新たな治療戦略の開発

Profile Information

Research Interests

Research Areas

Research History

Education

Committee Memberships

Papers

Misc.

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