2005年7月
Effect of chondroitin sulfate and hyaluronic acid on gene expression in a three-dimensional culture of chondrocytes
JOURNAL OF BIOSCIENCE AND BIOENGINEERING
- ,
- ,
- ,
- ,
- 巻
- 100
- 号
- 1
- 開始ページ
- 123
- 終了ページ
- 126
- 記述言語
- 英語
- 掲載種別
- 研究論文（学術雑誌）
- DOI
- 10.1263/jbb.100.123
- 出版者・発行元
- SOC BIOSCIENCE BIOENGINEERING JAPAN
The effect of glycosaminoglycan addition on a three-dimensional (3D) culture of porcine chondrocyte cells was investigated with a view to use in cartilage regenerative medicine. Chondroitin sulfate C increased the mRNA expression of type 2 collagen, while chondroitin sulfate A did not. Hyaluronic acid of high molecular weight markedly decreased the mRNA expression of both aggrecan and type 2 collagen, although hyaluronic acid of low molecular weight showed no apparent effect.
- リンク情報
-
- DOI
- https://doi.org/10.1263/jbb.100.123
- CiNii Articles
- http://ci.nii.ac.jp/naid/110002703755
- PubMed
- https://www.ncbi.nlm.nih.gov/pubmed/16233863
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000231989800020&DestApp=WOS_CPL
- ID情報
-
- DOI : 10.1263/jbb.100.123
- ISSN : 1389-1723
- CiNii Articles ID : 110002703755
- PubMed ID : 16233863
- Web of Science ID : WOS:000231989800020