論文

2021年5月1日

Miniaturized LED light source with an excitation filter for fluorescent imaging

Japanese Journal of Applied Physics
  • Mohamad Izzat Azmer
  • ,
  • Kiyotaka Sasagawa
  • ,
  • Erus Rustami
  • ,
  • Kenji Sugie
  • ,
  • Yasumi Ohta
  • ,
  • Makito Haruta
  • ,
  • Hironari Takehara
  • ,
  • Hiroyuki Tashiro
  • ,
  • Jun Ohta

60
SB
開始ページ
SBBG07
終了ページ
SBBG07
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.35848/1347-4065/abe5bf
出版者・発行元
IOP Publishing

In this study, we developed a miniaturized InGaN blue mu LED-based excitation source intended for an implantable lens-less brain imaging system. To enhance its implantability, the mu LED was thinned further through the laser lift-off process. A filtering component comprising a short-pass interference filter and a low-NA fiber optic plate (FOP), was loaded onto the mu LED. The addition of an interference filter reduced normal incident green-end band emissions from the mu LED by two orders of magnitude. The application of FOP enables the resolution of the angle-dependent problem of the interference filter. Further, a fluorescent imaging experiment was carried out on the proposed excitation source. The proposed device produced bright fluorescence images that are sufficient for implantable in vivo application. The thickness of the proposed excitation device was 180 mu m, making it suitable for implantable brain fluorescent imaging applications.

リンク情報
DOI
https://doi.org/10.35848/1347-4065/abe5bf
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000624518600001&DestApp=WOS_CPL
共同研究・競争的資金等の研究課題
ミクロからマクロまでシームレスに細胞と会話する光技術の開発
共同研究・競争的資金等の研究課題
レーザー剥離加工による低侵襲かつ高感度な刺入型脳機能イメージングデバイス
URL
https://iopscience.iop.org/article/10.35848/1347-4065/abe5bf
URL
https://iopscience.iop.org/article/10.35848/1347-4065/abe5bf/pdf
ID情報
  • DOI : 10.35848/1347-4065/abe5bf
  • ISSN : 0021-4922
  • eISSN : 1347-4065
  • Web of Science ID : WOS:000624518600001

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