NAKANO Daisuke

J-GLOBAL         Last updated: Jun 19, 2019 at 11:57
 
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Name
NAKANO Daisuke
Affiliation
Kagawa University
Section
Faculty of Medicine, Radiology
Job title
Assistant Professor

Research Areas

 
 

Academic & Professional Experience

 
2006
 - 
2008
 Vascular Biology Center, Medical College of Georgia, Postdoc
 

Published Papers

 
Effects of the novel nonsteroidal mineralocorticoid receptor blocker, esaxerenone (CS-3150), on blood pressure and urinary angiotensinogen in low-renin Dahl salt-sensitive hypertensive rats. Hypertens Res.
Li L, Guan Y, Kobori H, Morishita A, Koboara H, Masaki T, Nakano D, Nishiyama A.
Hypertens Res      2019   [Refereed]
Effect of the novel nonsteroidal selective mineralocorticoid receptor antagonist, esaxerenone (CS-3150), on blood pressure and renal injury in high salt-treated type 2 diabetic mice. Hypertens Res.
Bhuiyan SA, Rafiq K, Kobara H, Masaki T, Nakano D, Nishiyama A.
Hypertens Res      2019   [Refereed]
Simultaneous GLP-1 receptor activation and angiotensin receptor blockade increase natriuresis independent of altered arterial pressure in obese OLETF rats.
Rodriguez R, Moreno M, Lee AY, Godoy-Lugo JA, Nakano D, Nishiyama A, Parkes D, Awayda MS, Ortiz RM.
Hypertens Res   41(10) 798-808   2018   [Refereed]
Effect of a SGLT2 inhibitor on the systemic and intrarenal renin-angiotensin system in subtotally nephrectomized rats.
Li L, Konishi Y, Morikawa T, Zhang Y, Kitabayashi C, Kobara H, Masaki T, Nakano D, Hitomi H, Kobori H, Nishiyama A.
J Pharmacol Sci   137(2) 220-237   2018   [Refereed]
A novel approach to adenine-induced chronic kidney disease associated anemia in rodents.
Rahman A, Yamazaki D, Sufiun A, Kitada K, Hitomi H, Nakano D, Nishiyama A.
PLoS One   13(2) e0192531   2018   [Refereed]
Guanylyl cyclase a in both renal proximal tubular and vascular endothelial cells protects the kidney against acute injury in rodent experimental endotoxemia models.
Kitamura H, Nakano D, Sawanobori Y, Asaga T, Yokoi H, Yanagita M, Mukoyama M, Tokudome T, Kangawa K, Shirakami G, Nishiyama A.
Anesthesiology   129(2) 296-310   2018   [Refereed]
Chronic AT1 blockade improves glucose homeostasis in obese OLETF rats.
Rodriguez R, Minas JN, Vazquez-Medina JP, Nakano D, Parkes DG, Nishiyama A, Ortiz RM.
J Endocrinol   237(3) 271-284   2018   [Refereed]
Angiotensin receptor blockade improves cardiac mitochondrial activity in response to an acute glucose load in obese insulin resistant rats.
Thorwald M, Rodriguez R, Lee A, Martinez B, Peti-Peterdi J, Nakano D, Nishiyama A, Ortiz RM.
Redox Biol   14 371-378   2018   [Refereed]
A sodium-glucose cotransporter 2 inhibitor attenuates renal capillary injury and fibrosis by a vascular endothelial growth factor-dependent pathway after renal injury in mice.
Zhang Y, Nakano D, Guan Y, Hitomi H, Masaki T, Kobara H, Sugaya Y, Nishiyama A.
Kidney Int   62(4) 499-507   2018   [Refereed]
Angiotensin receptor and tumor necrosis factor-α activation contribute to glucose intolerance independent of systolic blood pressure in obese rats.
Rodriguez R, Lee A, Mathis KW, Broome HJ, Thorwald M, Martinez B, Nakano D, Nishiyama A, Ryan MJ, Ortiz RM.
Am J Physiol Renal Physiol   315(4) F1081-F1090   2018   [Refereed]
Effects of the selective chymase inhibitor, TEI-F00806, on intrarenal renin-angiotensin system in salt-treated angiotensin I-infused hypertensive mice.
Ansary TM, Urushihara M, Fujisawa Y, Nagata S, Urata H, Nakano D, Hirofumi H, Kitamura K, Kagami S, Nishiyama A.
Exp Physiol   103(11) 1524-1531   2018   [Refereed]
Cardiac Glutathione Levels Increase in Response to Glucose in Diabetic Rats.
Thorwald MA, Godoy-Lugo JA, Rodriguez GJ, Rodriguez MA, Jamal M, Kinoshita H, Nakano D, Nishiyama A, Forman HJ, Ortiz RM.
Free Radic Biol Med      2018   [Refereed]
A novel role of renin inhibitor in the complement cascade.
Nakano D, Nishiyama A.
Kidney Int   94(4) 650-652   2018   [Refereed]
Acute kidney injury to chronic kidney disease transition-insufficient cellular stress response.
Strausser SA, Nakano D, Souma T.
Curr Opin Nephrol Hypertens.   27(4) 314-322   2018   [Refereed]
Guan Y, NAKANO Daisuke, Zhang Y, Li L, Liu W, Nishida M, Kuwabara T, MORISHITA Asahiro, HITOMI Hirofumi, Mori K, Mukoyama M, MASAKI Tsutomu, HIRANO Katsuya, NISHIYAMA Akira
J. Pharmacol. Sci.   135(2) 81-88   2017   [Refereed]
Responses of renal hemodynamics and tubular functions to acute sodium–glucose cotransporter 2 inhibitor administration in non-diabetic anesthetized rats.
Ansary T, Fujisawa Y, Rahman A, Nakano D, Hitomi H, Kobara H, Masaki T, Titze JM, Kitada K, Nishiyama A.
Sci Rep   7(1) 9555   2017   [Refereed]
Roksnoer LCW, Heijnen BFJ, Nakano D, Peti-Peterdi J, Walsh SB, Garrelds IM, van Gool JMG, Zietse R, Struijker-Boudier HAJ, Hoorn EJ、Dacser AH.
Hypertension   67(5) 927-933   May 2016   [Refereed]
NAKANO Daisuke, Doi K, Kitamura H, Kuwabara T, Mori K, Mukoyama M, NISHIYAMA Akira
J am Soc Nephrol.   26(12) 3035-3044   Dec 2015   [Refereed]
Effect of dipeptidyl peptidase-4 inhibition on circadian blood pressure during the development of salt-dependent hypertension in rats.
Sufiun A, Rafiq K, Fujisawa Y, Rahman A, Mori H, Nakano D, Kobori H, Ohmori K, Masaki T, Kohno M, Nishiyama A.
Hypertens Res   38(4) 237-243   Apr 2015   [Refereed]
Moritoki M, Kadowaki T, Niki T, Nakano D, Soma G, Kobara H, Masaki T, Kohno M, Hirashima M
PLoS One.   9(8) 4   Apr 2013   [Refereed]
Role of (pro)renin receptor in angiotensin II-dependent and -independent EGF receptor transactivation.
Shibayama Y, Hitomi H, Nakano D, Kobori H, Mori H, Deguchi K, Masaki T, Ichihara A, Nishiyama A
Front Biosci   5 697-705-705   Jan 2013   [Refereed]
Sherajee SJ, Hujita Y, Rafig K, Nakano D, YOSHIDA Hirohito, Masaki T, KOHNO Masakazu, Hara T, Nishiysms A, Hitomi H(Sherajee SJ, Hujita Y, Rafig K, Nakano D, YOSHIDA Hirohito, Masaki T, KOHNO Masakazu, Hara T, Nisiyama A, Hitomi H)
Arterioscler Thromb Vasc Biol   32(2) 257-263   Feb 2012   [Refereed]
Angiotensin receptor blockade increases pancreatic insulin secretion and decreases glucose intolerance during glucose supplementation in a model of metabolic syndrome.
Rodriguez R, Viscarra JA, Minas JN, Nakano D, Nishiyama A, Ortiz RM
Endocrinology   153 1684-1695   2012   [Refereed]
Aldosterone induces p21-regulated apoptosis via increased synthesis an d secretion of tumour necrosis factor-α in human proximal tubular cells. Cl in Exp Pharmacol Physiol.
Kitada K, Nakano D, Hitomi H, Kobori H, Deguchi K, Mori H, Masaki T, Nishiyama A
Clin Exp Pharmacol Physiol   39 858-863   2012   [Refereed]
Angiotensin receptor blockade recovers hepatic UCP2 expression, aconitase and SDH activities, and ameliorates hepatic oxidative damage in insulin resistant rats.
Montez P, Thorwald MA, Rodriguez R, Viscarra JA, Vazquez-Medina JP, Nakano D, Peti-Peterdi J, Nishiyama A, Ortiz RM.
Endocrinology   153 5746-5759   2012   [Refereed]
HOSSAIN MOHAMMAD AKRAM, Kitagagi.S, Nakano D, Nishiyama A, Funamoto Y, Matsunaga T, Tsukamoto I, Yamaguchi F, Kamitori K, Dong Y, Hirata Y, Murao K, Toyoda Y, Tokuda M
Biochemical and Biophysical Research Communications, (in press)      2011
Programmed 11β-hydroxysteroid dehydrogenase type 2 reduction: a possible cause of adult-onset disease?
Nakano D, Nishiyama A
J Hypertens   29 201-203   2011   [Refereed]
The proximal tubular renin-angiotensin system during albuminuria.
Nakano D, Nishiyama A
J Hypertens   29 1292-1294   2011   [Refereed]
Du Jun, Fan Yu-Yan, Hirofumi Hitomi, Hideyasu Kiyomoto, Shoji Kimura, Chan-Ze Kong, Takahisa Noma, Masakazu Kohno, Akira Nishiyama, Daisuke Nakano
Am J Physiol Renal Physiol.   297(3,Pt.2) 802-808   2009
The efficacy of gene therapy for TGF-β in progressive diabetic nephropathy.
Nakano D, Kiyomoto H, Nishiyama A
Clin Exp Pharmacol Physiol   35 1275-1276   2008   [Refereed]
Hideaki Kawanishi, Nakano D
Clin. Exp. Pharmacol. Physiol.   34(4) 280-285   2007

Misc

 
Diuretic effects of sodium glucose cotransporter 2 inhibitors and their influence on the renin-angiotensin system.
Ansary TM, Nakano D, Nishiyama A.
Int J Mol Sci.      2019
Nrf2-related gene expression is impaired during a glucose challenge in type II diabetic rat hearts.
Thorwald MA, Godoy-Lugo JA, Rodriguez GJ, Rodriguez MA, Jamal M, Kinoshita H, Nakano D, Nishiyama A, Forman HJ, Ortiz RM.
Free Radic Biol Med.   130(1) 306-317   2019
Commentary for Aliskiren inhibits renin-mediated complement activation.
Nakano D, Nishiyama A.
Kidney Int.      2018

Conference Activities & Talks

 
Effects of the novel nonsteroidal mineralocorticoid receptor blocker, esaxerenone(CS-3150),on blood pressure and urinary angiotensinogen in low-renin dahl satl-sensitive hypertensive rats.
Nishiyama A, Nakano D, Kobori H, Li L.
ISN WCN2019   Apr 2019   
High Salt Intake Induces Catabolism Accompanied By Hepatic Urea Osmolyte Production And Decreases Renal Sympathetic Nerve Activity
Morisawa N, Kitada K, Yamazaki D, Nakano D, Fujisawa Y, Nishiyama A.
AHA Joint Hypertension 2018   Sep 2018   
Treatment with the SGLT2 Inhibitor Luseogliflozin after Ischemia/Reperfusion Attenuated Renal Fibrosis through Reversing the Endothelial Rarefaction in Mice.
Nakano D, Nishiyama A.
KIDNEY WEEK 2017   Nov 2017   
Esaxerenone (CS-3150), a non-steroidal selective mineralocorticoid receptor antagonist, elicits renoprotective effects in high salt-treated type 2 diabetic KKAy mice
Nishiyama A, Hitomi H, Nakano D.
ISN WCN2017   Apr 2017   
Renoprotective effect of LCZ696 in type2 diabetic rats with overt proteinuria.
Nishiyama A, Konishi Y, Morikawa T, Nakano D, Imanishi M
The 17th International SHR Symposium   Sep 2016   
Mouse glomerular injury reduced by blocking n-type calcium channel.
Guan Y, Nakano D, Yifan Z, Nishiyama A.
26th Meeting of the International Society of Hypertension   Sep 2016   
Effects of SGLT2 inhibitors on circadian rhythm of blood pressure in rats.
Rahman A, Takeshige Y, Fujisawa Y, Hitomi H, Nakano D, Nishiyama A.
26th Meeting of the International Society of Hypertension   Sep 2016   
Atrial natriuretic peptide improves urine flow at proximal tubules in septic acute kidney injury.
Kitamura H, Nakano D, Yifan Z, Nishiyama A.
26th Meeting of the International Society of Hypertension   Sep 2016   
Dipping pattern of blood pressure and renal injury in Dahl salt-sensitive hypertensive rats.
Nishiyama A, Sufiun A, Fujisawa Y, Rahman A, Nakano D, Hitomi H.
26th Meeting of the International Society of Hypertension   Sep 2016   
Role of (pro) renin receptor in the activation of wnt/ β-catenin pathway in colon cancer.
Wang J, Shibayama Y, Nakano D, Hitomi H, Nishiyama A.
26th Meeting of the International Society of Hypertension   Sep 2016   
Hepatocyte nuclear factor -5 acts as a glucose-responsive element of human angiotensinogen promoter.
Wang J, Kobori H, Shibayama Y, Nakano D, Hitomi H, Nishiyama A.
26th Meeting of the International Society of Hypertension   Sep 2016   
Intravital imaging of oxidative stress in renal proximal tubules.
Nishiyama A, Nakano D
The 9th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide   May 2016   
A sodium-glucose co-transporter 2 inhibitor prevents abnormality of circadian rhythm of blood pressure in salt-treated obese rats.
Nishiyama A, Nakano D, Ogata H, Takeshige Y
American Heart Association Scientific Session   Oct 2015   
Effect of diuretics on SGLT2 inhibitor-induced changes in blood pressure and renal function in obese metabolic syndrome rats.
第58回日本腎臓学会学術総会   Jun 2015   
Role of endothelial glycocalyx in peritubular capillaries during acute kidney injury
第44回日本心脈管作動物質学会   2015   
Mouse podocytes injury is reduced by bloking N-type calcium channel.
第58回日本腎臓学会学術総会   2015   
Remote ischemic preconditioning of hind-limb in anesthetized mice did not protect kidney from ischemia/reperfusion injury
第58回日本腎臓学会学術総会   2015   
Reduction of Tubular Flow Rate as a Mechanism of Oliguria in Endotoxemia Revealed by Intravital Imaging
Nakano D, Doi K, Kuwabara T, Mori K, Masashi Mukoyama M, Nishiyama A
American Society of Nepjrology, Kidney week 2014   Nov 2014   
Effect of Dipeptidyl Peptidase-4 Inhibition on Blood Pressure and its Dipping Pattern in Dahl Salt-Sensitive Rats.
Nishiyama A, Fujisawa Y, Rahman A, Nakano D, Rafiq K, Kobori H, Sufiun A
High Blood Pressure Research   Sep 2014   
Effects of Diuretics on Sglt2 Inhibitor-induced Changes in Urinary Sodium Excretion Rate In Obese Metabolic Syndrome Rats.
Nishiyama A, Fujisawa Y, Sufiun A, Rafiq K, Nakano D, Kobori H, Rahman A
High Blood Pressure Research   Sep 2014   
Effects of high salt and renal denervation on blood pressure and dipping pattern in rats treated with adenine.
Sufiun A, Rahman A, Kitada K, Fujisawa Y, Nakano D, Rafiq K, Nishiyama A
The 14th Asian Pacific Congress of Nephrology   May 2014   
Effect of vildagliptin, a dpp-4 inhibitor, on blood pressure and dippiping pattern in dahl salt-sensitive rats.
Sufiun A, Fujisawa Y, Rahman A, Nakano D, Rafiq K, Kobori H, Nishiyama A
The 14th Asian Pacific Congress of Nephrology   May 2014   
Renal sympathetic denervation suppresses insulin resistance in pre-diabetic obese oletf rats.
Rafiq K, Sherajee S, Fujisawa Y, Mogi M, Rahman A, Sufiun A, Nakano D, Koepsell H, Nishiyama A
The 14th Asian Pacific Congress of Nephrology   May 2014   
Effects of renal sympathetic denervation on blood pressure and glucose metabolism in obese type 2 diabetic rats.
Rafiq K, Sherajee S, Fujisawa Y, Mogi M, Sufiun A, Rahman A, Nakano D, Koepsell H, Nishiyama A
The 14th Asian Pacific Congress of Nephrology   May 2014   
Effects of a SGLT2 inhibitor empagliflozin, on blood pressure and urinary excretion of sodium in salt-treated metabolic syndrome rats.
Takeshige Y, Fujisawa Y, Sufiun A, Rahman A, Rafiq K, Nakano D, Ogata H
The 14th Asian Pacific Congress of Nephrology   May 2014   
Multi photon imaging of microcirculation in the septic kidney.
Nakano D, Nishiyama A
The 18th International Vascular Biology Meeting   Apr 2014   
Contribution of endothelial glycocalyx in renal peritubular capillaries in acute kidney injury
2014   
Suppression of insulin resistance by renal sympathetic denervation in obese rats.
Annual Meetings of the American Society of Nephrology   Nov 2013   
Renal sympahtetic denervation improves insulin resisitance in obese rats.
第17回日本心血管内分泌代謝学会   Nov 2013   
An Iron Chelator, Deferasirox, Prevents Renal Iron Accumulation and Macrophage Infiltration But Not Cell Senescence inType 1 Diabetic Mice
High Blood Pressure Research   Sep 2013   
P21 is Essential for the Beneficical Effects of Renal Ischemic Preconditioning in Ischemic Acute Kidney Injury
High Blood Pressure Research   Sep 2013   
Endothelial Cell-Derived ET--1 Contributes to the Severity of Septic Kidney Injury
International Conference on Endothelin   Sep 2013   
Renal iron accumulation in type 1 diabetic mice is independent of cell senescence
Morita T, Nakano D, Kitada K, Nishiyama A
World Congress of Nephrology   May 2013   
Angiotensin Receptor Activation Contributes to Glucose Intolerance and Increased Insulin Resistance Independent of Elevated Systolic Blood Pressure Adiposity and Dyslipidema in a Model of Metabolic Syndrome
High Blood Pressure Research   2013   
Effect of high salt on blood pressure in adenine-induced renal injury in rats
第42回日本心脈管作動物質学会   2013   
Sympathetic renal denervation suppresses insulin resistance in type 2 diabetic rats.
第2回神経研究EXPO   2013   
Roles of Na+/H+ exchanger type 1 and intracellular pH in angiotensin II-induced reactive oxygen species generation and podocyte apoptosis.
Annual Meetings of the American Society of Nephrology   Nov 2012   
Oxidative stress-induced glomerular mineralocorticoid recepter activation limits the benefit of salt reduction in Dahl salt-sensitive hypertensive rats.
24th Scientific Meeting of the International Society of Hypertension   Oct 2012   
Does iron cause cell senescence and renal inflammation in diabetic mouse model?
The Fourth Kagawa University- Chiang Mai University Joint Symposium 2012   Sep 2012   
Roles of NHE-1 and intracellular pH in Angiotensin II-induced reactive oxygen species generation and podocyte apoptosis
The Fourth Kagawa University- Chiang Mai University Joint Symposium 2012   Sep 2012   
Adenine induced renal injury with severe anemia in rat and mice
The Fourth Kagawa University- Chiang Mai University Joint Symposium 2012   Sep 2012   
Effect of high salt on blood pressure in adenine-induced renal injury in rats
The Fourth Kagawa University- Chiang Mai University Joint Symposium 2012   Sep 2012   
Restoration of glomerular and tubulointerstitial injuries by dietary salt reduction with combination therapy of olmesartan and azelnidipine in dahl salt-sensitive rats
The Fourth Kagawa University- Chiang Mai University Joint Symposium 2012   Sep 2012   
Aldosterone Evokes senescence-associated secreting phenotype and subsequent apoptsis in proximal tubular cells
High Blood Pressure Research   Sep 2012   
Telmisartan but not tempol improves the already established renal cell senescence in type 2 diabetic rats
High Blood Pressure Research   Sep 2012   
Azelnidipine enhances protective effects of olmesartan against BBB and renal injuries in type 2 diabetic mice
第35回日本高血圧学会総会   Sep 2012   
Renal sympathetic denervation suppresses de novo albuminuria in rats with aortic regurgitation
第35回日本高血圧学会総会   Sep 2012   
Renal sympathetic denervation suppresses de novo albuminuria rats with aortic regurgitation
第121回日本薬理学会近畿部会   Jun 2012   
Azelnidipine enhances protective effects of olmesartan against BBB and renal injuries in type 2 dibetic mice
第121回日本薬理学会近畿部会   Jun 2012   
Roles of NHE-1 and intracellular pH in angiotensin Ⅱ-induced reactive oxygen species generation and podocyte apoptosis
第121回日本薬理学会近畿部会   Jun 2012   
Restoration of glomerular and tubulointerstitial injuries by salt withdrawal with combination therapy of olmesartan and azelnidiine in Dahl salt-sensitive rats rats
第121回日本薬理学会近畿部会   Jun 2012   
Activation of Mineralocorticoid Receptor by Oxidative Stress Induces Proteinuria After Salt Withdrawal in High Salt Diet-Fed Dahl Salt-Sensitive Rats
High Blood Pressure Research   Sep 2011   
High Glucose-Induced Increase in p21 Causes Cellular Senescence in Porximal Tubules of Diabetic Nephropathy
High Blood Pressure Research   Sep 2011   
Angiotensin Ⅱ increased renal p21 expression independent of subsequent increase in aldosterone in angiotensin Ⅱ-salt model
World Congress of Nephrology   Apr 2011   
Effect of aldosterone on vascular insulin resistance via up-regulation of IGF-1 receptor and its hybrid receptor
World Congress of Nephrology   Apr 2011   
Role of epidermal growth factor receptor transactivation in cellular signaling mediated by (pro)renin receptor
第40回日本心脈管作動物質学会   Feb 2011   
細胞内pHと酸化ストレスを介したアンジオテンシンIIによるポドサイト障害機序の解明
第40回日本心脈管作動物質学会   Feb 2011   
Aldosterone induces insulin resistance via up-regulation of IGF-1 receptor and its hybrid receptor in vitro and in vivo
第40回日本心脈管作動物質学会   Feb 2011   
Effect of efonidipine on TGF-B1-and Smad2-dependent protein synthesis in rat cardiac fibroblasts
第40回日本心脈管作動物質学会   Feb 2011   
Aliskiren suppressed the development of renal injury in valsartan-treated KKAy mice
第40回日本心脈管作動物質学会   Feb 2011   
The role of renal sympathetic nerve in reno-protective effects of cilnidipine in spontaneously hypertensive rat
第40回日本心脈管作動物質学会   Feb 2011   
Reno-protective effects of clinidipine in spontaneously hypertensive rats; effect independent of sympathetic nerve inhibition.
The 13th China - Japan Joint Hypertension Symposium   2011   
Effects of aliskiren on podocyte injury and albuminuria in type 2 diabetic mice.
The 13th China - Japan Joint Hypertension Symposium   2011   
Renal sympathetic denervation suppresses new onset of albuminuria in the rat with aortic regurgitation
第15回日本心血管内分泌代謝学会学術総会   2011   
Contributions of renal sympathetic nervous system to reno-protective effects of cilnidipine in spontaneously hypertensive rats
第120回日本薬理学会近畿支部   2011   
Reno-protective effects of clinidipine in spontaneously hypertensive rats; effect independent of sympathetic nerve inhibition.
The 13th China - Japan Joint Hypertension Symposium   2011   
Effects of aliskiren on podocyte injury and albuminuria in type 2 diabetic mice.
The 13th China - Japan Joint Hypertension Symposium   2011   
Cilnidipine provided renal protection mainly through inhibiting N type calcium channel expression on podocyte
第21回日本循環薬理学会   2011   
Angiotensin Ⅱ induced apoptotic changes in mouse podocytes through Na+/H+ exchanger-1-dependent intracellular alkalization and oxidant production
第21回日本循環薬理学会   2011   
Prorenin induces vascular smooth muscle cell proliferation and hypertrophy via EGF receptor-mediated ERK and Akt activation pathway
The 14th Scientific Session of the Society of Cardiovascular Endocrinology and Metabolism   2010   
Mechanical stretch augments insulin-induced vascular smooth muscle cell proloferation by upregulation of insulin-like growth factor-1 receptor
14th International Congress of Endocrinology   2010   
The effect of childhood obese or lean on the adulthood insulin resisitance in OLETF rats
14th International Congress of Endocrinology   2010   
Glucocorticoid receptor plays an indispensable in mineralocorticoid receptor-dependent transcription/role of GR in MR-dependent transcription
14th International Congress of Endocrinology   2010   
High sodium augments angiotensin Ⅱ-induced proliferation of rat vascular smooth muscle cell throuth an ERK1/2-dependnt pathway
14th International Congress of Endocrinology   2010   
Prorenin induces vascular smooth muscle cell proliferation and hypertrophy via EGF receptor-mediated ERK and Akt activation pathway
14th International Congress of Endocrinology   2010   
Aldosterone Induces Proximal Tubular Senescence through Minerlalocorticoid Receptor/p21-Dependent Pathway
International Symposium on Aldosterone and Related Substances in Hypertension 2010   2010   
Effects of Eplerenone on Gucorticoid-Induced Renal Injury in Adrenalectomized Rats
International Symposium on Aldosterone and Related Substances in Hypertension 2010   2010   
Aldosterone induces renal proximal tubular cell senescence
ISN Nexus   2010   
High sodium augments angiotensin Ⅱ-induced proliferation of rat vascular smooth muscle cell throuth ERK1/2-dependnt pathway
ISN Nexus   2010   
Prorenin induces vascular smooth muscle cell proliferation and hypertrophy via EGF receptor-mediated ERK and Akt activation pathway
ISN Nexus   2010   
Mechanical stretch augments insulin-induced vascular smooth muscle cell proloferation by upregulation of insulin-like growth factor-1 receptor
ISN Nexus   2010   
Mechanical stretch potentiates angiotensinⅡ-induced porliferation in spontaneously hypertensive rat vascular smooth muscle cells
ISN Nexus   2010   
Clinidipine, an L/N-type calcium channel blocker, suppresses podocyte injury and proteinuria in metabolic syndrome rats
ISN Nexus   2010   
Aldosterone accelerates the insulin resistance induced by high-fructose in rats
The Third International Aldosterone Forum in Japan   2010   
Aldosterone induces insulin resistance via up-regulation of IGF-1 receptor and its hybird receptor in vitro and in vivo
The Third International Aldosterone Forum in Japan   2010   
Reno-protective effect of cilnidipine in metabolic syndrome rats;possible involvement of n-type calcium channel in podocyte
12th Asian Pacific Congress of Nephrology   2010   
Effects of prorenin of vascular smooth muscle cell proliferation and hypertrophy via egf receptor-mediated erk and akt activation pathway
12th Asian Pacific Congress of Nephrology   2010   
Childhood calorie restriction attenuates the development of proteinuria but not insulin resistance in spontaneously obese rats
12th Asian Pacific Congress of Nephrology   2010   
Olmesartan ameliorates the impairment of renal function in aortic regurgitation model rats
12th Asian Pacific Congress of Nephrology   2010   
Aldosterone induces cell senescence in the renal proximal tubular cells via P21-dependent manner
12th Asian Pacific Congress of Nephrology   2010   
Mineralocorticoid receptor blockade suppresses hydrocortisone-induced renal injury in adrenalectomized rats
12th Asian Pacific Congress of Nephrology   2010   
Effects of high sodium and angiotensin Ⅱ on proliferation of rat vascular smooth muscle cell via erk1/2-dependent pathway
12th Asian Pacific Congress of Nephrology   2010   
Effects of mechanical stretch on insulin-induced vascular smooth muscle cell proliferation via upregulation of insulin-like growth factor -1 receptor
12th Asian Pacific Congress of Nephrology   2010   
Effects of mechanical stretch on angiotensin Ⅱ-induced cell proliferation in spontaneously hypertensive rat vascular smooth muscle cells
12th Asian Pacific Congress of Nephrology   2010   
Olmesartan ameliorates the impairment of renal function in aortic regurgitation model rats
The 6th International Conferernce on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide   2010   
Reno-protective effect of cilnidipine in metabolic syndrome rats;possible involvement of n-type calcium channel in podocyte
The 6th International Conferernce on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide   2010   
Role of the medullary endothelin-1 in regulating Na+ excretion
The 2010 FASEB Summer Research Conferene on "Renal Hemodynamics: Biomolecular Control Mechanisms Integrating Vascular and Tubular Function   2010   
Aldosterone induces insulin resistance via up-regulation of IGF-1 receptor and its hybird receptor in vitro and in vivo
第117回日本薬理学会近畿支部   2010   
Aldosterone induces cellular senescence in the kidney via mineralocorticoid/p21-dependent pathway
2010 APS Conference: Inflammation, Immunity and Cardiovascular Disease   2010   
Aldosterone shows an additional effect on glucose tolerance induced by high-fructose in rats
第33回日本高血圧学会総会   2010   

Association Memberships

 
 

Research Grants & Projects

 
the role of renlal medulla on hypertension