Masahiko IMAI

J-GLOBAL         Last updated: Oct 24, 2019 at 10:37
Masahiko IMAI
Hoshi University

Research Areas


Awards & Honors

Oct 2016
Fujiki aword, Japanese society for retinoid research
May 2015
Hoshi University Otani Research Grants

Published Papers

Izumisawa T, Kaneko T, Soma M, Imai M, Wakui N, Hasegawa H, Horino T, Takahashi N
Biological & pharmaceutical bulletin      Sep 2019   [Refereed]
Kake T, Imai M, Takahashi N
Experimental dermatology   28(9) 1044-1050   Jul 2019   [Refereed]
Imai M, Yokoe H, Tsubuki M, Takahashi N
Biological & pharmaceutical bulletin   42(7) 1134-1139   Jul 2019   [Refereed]
Takahashi N, Kake T, Hasegawa S, Imai M
Journal of oleo science      Jul 2019   [Refereed]
Hasegawa S, Imai M, Yamasaki M, Takahashi N, Fukui T
Biochemical and biophysical research communications   495(1) 652-658   Jan 2018   [Refereed]
Takahashi N, Koyama S, Hasegawa S, Yamasaki M, Imai M
Bioorganic & medicinal chemistry letters   27(20) 4664-4672   Oct 2017   [Refereed]
Sakai A, Imai M, Takahashi K, Hasegawa S, Yamasaki M, Ohba T, Takahashi N
Biochimica et biophysica acta   1861(2) 276-285   Feb 2017   [Refereed]
Li C, Imai M, Yamasaki M, Hasegawa S, Takahashi N
Biological & pharmaceutical bulletin      Jan 2017   [Refereed]
Li C, Imai M, Hasegawa S, Yamasaki M, Takahashi N
Biological & pharmaceutical bulletin      Jan 2017   [Refereed]
Takahashi N, Ohba T, Imai M, Hasegawa S, Takahashi K, Yamasaki M, Kameoka Y
Biochimica et biophysica acta   1861(12 Pt A) 2011-2019   Dec 2016   [Refereed]
Hasegawa S, Inoue D, Yamasaki M, Li C, Imai M, Takahashi N, Fukui T
FEBS letters   590(11) 1592-1601   Jun 2016   [Refereed]
Yamasaki M, Hasegawa S, Imai M, Takahashi N, Fukui T
Biochemical and biophysical research communications   473(2) 654-661   Apr 2016   [Refereed]
Li C, Imai M, Matsuura T, Hasegawa S, Yamasaki M, Takahashi N
Biological & pharmaceutical bulletin      Jan 2016   [Refereed]
Katsuhiko Takahashi, Natsumi Uchida, Chisato Kitanaka, Chiaki Sagara, Masahiko Imai, Noriko Takahashi
FEBS Open Bio   5 571-578   Jul 2015   [Refereed]
© 2015 The Authors. Published by Elsevier B.V. Vitamin A has preventive effects on obesity. All-. trans retinoic acid (ATRA), the active form of vitamin A, inhibits lipid accumulation in 3T3-L1 cells in an experimental adipogenesis model. We found...
Masahiko Imai, Takaya Kumaoka, Makiko Hosaka, Yui Sato, Chuan Li, Masashi Sudoh, Yoshiko Tamada, Hiromasa Yokoe, Setsu Saito, Masayoshi Tsubuki, Noriko Takahashi
Bioorganic and Medicinal Chemistry   23(13) 3788-3795   Jan 2015   [Refereed]
© 2015 Elsevier Ltd.All rights reserved. Obesity is a risk factor associated with several lifestyle-related diseases, for example, diabetes, high blood pressure, hyperlipidemia and cancer. Caffeic acid 2-phenylethyl ester (CAPE, 1), a naturally-oc...
Noriko Takahashi, Masahiko Imai, Yu Komori
Bioorganic and Medicinal Chemistry   22(17) 4677-4683   Sep 2014   [Refereed]
Melanin protects the skin against ultraviolet (UV) rays. It is produced in excess by UV radiation, which causes skin disorders and pigmentation. Retinoic acid (RA) decreases the levels of epidermal melanin by suppressing the expression of melanoge...
Yu Komori, Masahiko Imai, Takayasu Yamauchi, Kimio Higashiyama, Noriko Takahashi
Bioorganic and Medicinal Chemistry   22(15) 3994-4000   Aug 2014   [Refereed]
Tyrosinase is involved in the synthesis of melanin in the skin and hair as well as neuromelanin in the brain. This rate limiting enzyme catalyzes two critical steps (reactions) in melanogenesis; the hydroxylation of tyrosine to form DOPA and the s...
Hidetomo Kikuchi, Hidetomo Kikuchi, Hidetomo Kikuchi, Bo Yuan, Bo Yuan, Eisuke Yuhara, Masahiko Imai, Ryota Furutani, Shin Fukushima, Shingo Hazama, Chieko Hirobe, Kunio Ohyama, Norio Takagi, Hiroo Toyoda
International Journal of Oncology   45(2) 843-852   Jan 2014   [Refereed]
We have demonstrated that an extract from the ripe fruit of Vitex angus-castus (Vitex), might be a promising anticancer candidate. In order to further provide a molecular rationale for clinical development in anticancer therapy, a detailed mechani...
Kikuchi H, Yuan B, Nishimura Y, Imai M, Furutani R, Kamoi S, Seno M, Fukushima S, Hazama S, Hirobe C, Ohyama K, Hu XM, Takagi N, Hirano T, Toyoda H
International journal of oncology   43(6) 1976-1984   Dec 2013   [Refereed]
Takahashi N, Takeda K, Imai M
Bioorganic & medicinal chemistry   21 6015-6021   Oct 2013   [Refereed]
Imai M, Takahashi N
Bioorganic & medicinal chemistry   20 2520-2526   Apr 2012   [Refereed]
Imai M, Yuan B, Kikuchi H, Saito M, Ohyama K, Hirobe C, Oshima T, Hosoya T, Morita H, Toyoda H
Advances in Biological Chemistry   2 20-28   Feb 2012   [Refereed]
Takahashi N, Egawa R, Imai M, Takahashi K, Ohba T, Imaizumi M
Cancer letters   297(2) 252-258   Nov 2010   [Refereed]
Imai M, Kikuchi H, Denda T, Ohyama K, Hirobe C, Toyoda H
Cancer letters   276 74-80   Apr 2009   [Refereed]
Ohyama K, Akaike T, Imai M, Toyoda H, Hirobe C, Bessho T
The international journal of biochemistry & cell biology   37 1496-1510   Jul 2005   [Refereed]

Conference Activities & Talks

Anti-cancer activity of human refractory tumor cells by natural product related compounds
Masahiko IMAI
The 28th Symposium of Retinoids, Japanese Society for Retinoid Research   18 Nov 2017