Karagiannis P, Takahashi K, Saito M, Yoshida Y, Okita K, Watanabe A, Inoue H, Yamashita JK, Todani M, Nakagawa M, Osawa M, Yashiro Y, Yamanaka S, Osafune K
Physiological Reviews 99(1) 79-114 Jan 2019 [Refereed]
Mae SI, Ryosaka M, Toyoda T, Matsuse K, Oshima Y, Tsujimoto H, Okumura S, Shibasaki A, Osafune K
495(1) 954-961 Jan 2018 [Refereed]
Adrenergic receptor agonists induce the differentiation of pluripotent stem cell-derived hepatoblasts into hepatocyte-like cells.
Kotaka M, Toyoda T, Yasuda K, Kitano Y, Okada C, Ohta A, Watanabe A, Uesugi M, Osafune K.
Scientific Reports. 7(1) 16734 Dec 2017 [Refereed]
Significance of dopamine D1 receptor signalling for steroidogenic differentiation of human induced pluripotent stem cells
Matsuo K, Sone M, Honda-Kohmo K, Toyohara T, Sonoyama T, Taura D, Kojima K, Fukuda Y, Ohno Y, Inoue M, Ohta A, Osafune K, Nakao K, Inagaki N
Scientific Reports 7(1) 15120 Nov 2017 [Refereed]
Human pluripotent stem cell-derived erythropoietin-producing cells ameliorate renal anemia in mice
Hitomi H, Kasahara T, Katagiri N, Hoshina A, Mae SI, Kotaka M, Toyohara T, Rahman A, Nakano D, Niwa A, Saito MK, Nakahata T, Nishiyama A, Osafune K
9 409 Sep 2017 [Refereed]
Identification of a small molecule that facilitates the differentiation of human iPSCs/ESCs and mouse embryonic pancreatic explants into pancreatic endocrine cells
Kondo Y, Toyoda T, Ito R, Funato M, Hosokawa Y, Matsui S, Sudo T, Nakamura M, Okada C, Zhuang X, Watanabe A, Ohta A, Inagaki N and Osafune K
60(8) 1454-1466 Aug 2017 [Refereed]
Rho-associated kinases and non-muscle myosin IIs inhibit the differentiation of human iPSCs to pancreatic endoderm cells
Toyoda T, Kimura A, Tanaka H, Ameku T, Mima A, Hirose Y, Nakamura M, Watanabe A, and Osafune K
9(2) 419-428 Aug 2017 [Refereed]
Small molecule AT7867 proliferates PDX1-expressing pancreatic progenitor cells derived from human pluripotent stem cells
Kimura A, Toyoda T, Nishi Y, Nasu M, Ohta A and Osafune K
24 61-68 Aug 2017 [Refereed]
Modelling urea-cycle disorder citrullinemia type 1 with disease-specific iPSCs
Yoshitoshi-Uebayashi EY, Toyoda T, Yasuda K, Kotaka M, Nomoto K, Okita K, Yasuchika K, Okamoto S, Takubo N, Nishikubo T, Soga T, Uemoto S, Osafune K
486(3) 613-619 May 2017 [Refereed]
Redefining definitive endoderm subtypes by robust induction of human induced pluripotent stem cells
Matsuno K, Mae SI, Okada C, Nakamura M, Watanabe A, Toyoda T, Uchida E, Osafune K
92(5) 281-290 Dec 2016 [Refereed]
Transcriptional Analysis of Intravenous Immunoglobulin Resistance in Kawasaki Disease Using an Induced Pluripotent Stem Cell Disease Model
Ikeda K, Mizoro Y, Ameku T, Nomiya Y, Mae SI, Matsui S, Kuchitsu Y, Suzuki C, Hamaoka-Okamoto A, Yahata T, Sone M, Okita K, Watanabe A, Osafune K, Hamaoka K
81(1) 110-118 Nov 2016 [Refereed]
Novel Regenerative Therapy for Acute Kidney Injury
Toyohara T, Osafune K
2 34 Aug 2016 [Refereed]
Identification of MMP1 as a novel risk factor for intracranial aneurysms in ADPKD using iPSC models
Ameku T, Taura D, Sone M, Numata T, Nakamura M, Shiota F, Toyoda T, Matsui S, Araoka T, Yasuno T, Mae SI, Kobayashi H, Kondo N, Kitaoka F, Amano N, Arai S, Ichisaka T, Matsuura N, Inoue S, Yamamoto T, Takahashi K, Asaka I, Yamada Y, Ubara Y, Muso E, Fukatsu A, Watanabe A, Sato Y, Nakahata T, Mori Y, Koizumi A, Nakao K, Yamanaka S & Osafune K
60 30013 Jul 2016 [Refereed]
Cell therapy using human induced pluripotent stem cell-derived renal progenitors ameliorates acute kidney injury in mice
Toyohara T, Mae SI, Sueta SI, Inoue T, Yamagishi Y, Kawamoto T, Kasahara T, Hoshina A, Toyoda T, Tanaka H, Araoka T, Sato-Otsubo A, Takahashi K, Sato Y, Yamaji N, Ogawa S, Yamanaka S, Osafune K
4(9) 980-992 Sep 2015 [Refereed]
Directing the differentiation of pluripotent stem cells to renal endpoints.
Kenji Osafune
Kidney Development, Repair and Regeneration 473-490 Sep 2015 [Refereed]
Efficient Detection and Purification of Cell Populations Using Synthetic MicroRNA Switches
Miki K, Endo K, Takahashi S, Funakoshi S, Takei I, Katayama S, Toyoda T, Kotaka M, Takaki T, Umeda M, Okubo C, Nishikawa M, Oishi A, Narita M, Miyashita I, Asano K, Hayashi K, Osafune K, Yamanaka S, Saito H, Yoshida Y
16(6) 699-711 Jul 2015 [Refereed]
Vascularized and complex organ buds generated from diverse tissues via mesenchymal cell-driven condensation.
Takebe T, Enomura M, Yoshizawa E, Kimura M, Koike H, Matsuzaki T, Yamazaki T, Toyohara T, Osafune K, Nakauchi H, Yoshikawa HY, Taniguchi H
16(5) 556-565 May 2015 [Refereed]
Kidney regeneration from human iPSCs
Mae S, Osafune K
20(2) 171-177 Apr 2015 [Refereed]
Cell aggregation optimizes the differentiation of human ESCs and iPSCs into pancreatic bud-like progenitor cells.
Toyoda T, Mae S, Tanaka H, Kondo Y, Funato M, Hosokawa Y, Sudo T, Kawaguchi Y, Osafune K
14(2) 185-197 Mar 2015 [Refereed]
Generation of Alveolar Epithelial Spheroids via Isolated Progenitor Cells from Human Pluripotent Stem Cells
Gotoh S, Ito I, Nagasaki T, Yamamoto Y, Konishi S, Korogi Y, Matsumoto H, Muro S, Hirai T, Funato M, Mae S, Toyoda T, Sato-Otsubo A, Ogawa S, Osafune K, Mishima M
3(3) 394-403 Sep 2014 [Refereed]
Functional analysis of iPSC-derived myocytes from a patient with carnitine palmitoyltransferase II deficiency
Yasuno T, Osafune K, Sakurai H, Asaka I, Tanaka A, Yamaguchi S, Yamada K, Hitomi H, Arai S, Kurose Y, Higaki Y, Sudo M, Ando S, Nakashima H, Saito T, Kaneoka H
448(2) 175-181 May 2014 [Refereed]
Cell therapy for kidney injury: different options and mechanisms – Kidney progenitor cells
Osafune K
126(2) 64 May 2014 [Refereed]
Induction of pluripotency in human somatic cells via a transient state resembling primitive streak-like mesendoderm
Takahashi K, Tanabe K, Ohnuki M, Narita M, Sasaki A, Yamamoto M, Nakamura M, Sutou K, Osafune K, Yamanaka S
K. Ohnishi; K. Semi; T. Yamamoto; M. Shimizu; A. Tanaka; K. Mitsunaga; K. Okita; K. Osafune; Y. Arioka; T. Maeda; H. Soejima; H. Moriwaki; S. Yamanaka; K. Woltjen; Y. Yamada
M. Nakagawa; Y. Taniguchi; S. Senda; N. Takizawa; T. Ichisaka; K. Asano; A. Morizane; D. Doi; J. Takahashi; M. Nishizawa; Y. Yoshida; T. Toyoda; K. Osafune; K. Sekiguchi; S. Yamanaka
T. Hitomi; T. Habu; H. Kobayashi; H. Okuda; K.H. Harada; K. Osafune; D. Taura; M. Sone; I. Asaka; T. Ameku; A. Watanabe; T. Kasahara; T. Sudo; F. Shiota; H. Hashikata; Y. Takagi; D. Morito; S. Miyamoto; K. Nakao; A. Koizumi
Biochemical and Biophysical Research Communications 439(4) 419-426 Oct 2013 [Refereed]
T. Hitomi; T. Habu; H. Kobayashi; H. Okuda; K.H. Harada; K. Osafune; D. Taura; M. Sone; I. Asaka; T. Ameku; A. Watanabe; T. Kasahara; T. Sudo; F. Shiota; H. Hashikata; Y. Takagi; D. Morito; S. Miyamoto; K. Nakao; A. Koizumi
Biochemical and Biophysical Research Communications 438(1) 13-19 Aug 2013 [Refereed]
Downregulation of Securin by the variant RNF213 R4810K reduces angiogenic activity of induced pluripotent stem cell-derived vascular endothelial cells from moyamoya patients.
Hitomi T, Habu T, Kobayashi H, Okuda H, Harada KH, Osafune K, Taura D, Sone M, Asaka I, Ameku T, Watanabe A, Kasahara T, Sudo T, Shiota F, Hashikata H, Takagi Y, Morito D, Miyamoto S, Nakao K, Koizumi A
A. Nasu; M. Ikeya; T. Yamamoto; A. Watanabe; Y. Jin; Y. Matsumoto; K. Hayakawa; N. Amano; S. Sato; K. Osafune; T. Aoyama; T. Nakamura; T. Kato; J. Toguchida
Mae SI, Shono A, Shiota F, Yasuno T, Kajiwara M, Gotoda-Nishimura N, Arai S, Sato-Otubo A, Toyoda T, Takahashi K, Nakayama N, Cowan CA, Aoi T, Ogawa S, McMahon AP, Yamanaka S, Osafune K.
Nat.Commun. 4 1367 Jan 2013 [Refereed]
[iPS cell technology-based strategies for the treatment of diabetic nephropathy].
K. Osafune
Nihon rinsho. Japanese journal of clinical medicine 70 Suppl 5 419-423 2012 [Refereed]
