2010年10月
In vitro regeneration of kidney from pluripotent stem cells
EXPERIMENTAL CELL RESEARCH
- 巻
- 316
- 号
- 16
- 開始ページ
- 2571
- 終了ページ
- 2577
- 記述言語
- 英語
- 掲載種別
- DOI
- 10.1016/j.yexcr.2010.04.034
- 出版者・発行元
- ELSEVIER INC
Although renal transplantation has proved a successful treatment for the patients with end-stage renal failure, the therapy is hampered by the problem of serious shortage of donor organs. Regenerative medicine using stem cells, including cell transplantation therapy, needs to be developed to solve the problem. We previously identified the multipotent progenitor cells in the embryonic mouse kidney that can give rise to several kinds of epithelial cells found in adult kidney, such as glomerular podocytes and renal tubular epithelia. Establishing the method to generate the progenitors from human pluripotent stem cells that have the capacity to indefinitely proliferate in vitro is required for the development of kidney regeneration strategy. We review the current status of the research on the differentiation of pluripotent stem cells into renal lineages and describe cues to promote this research field. (C) 2010 Elsevier Inc. All rights reserved.
- リンク情報
-
- DOI
- https://doi.org/10.1016/j.yexcr.2010.04.034
- J-GLOBAL
- https://jglobal.jst.go.jp/detail?JGLOBAL_ID=201002216083098061
- CiNii Articles
- http://ci.nii.ac.jp/naid/120002511354
- PubMed
- https://www.ncbi.nlm.nih.gov/pubmed/20451514
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000281305800004&DestApp=WOS_CPL
- ID情報
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- DOI : 10.1016/j.yexcr.2010.04.034
- ISSN : 0014-4827
- J-Global ID : 201002216083098061
- CiNii Articles ID : 120002511354
- PubMed ID : 20451514
- Web of Science ID : WOS:000281305800004