J-GLOBAL         Last updated: Sep 19, 2019 at 00:33
Doshisha University
Office for Research Initiatives and Development
PhD.(Osaka University)

Research Areas


Published Papers

Shingo Shimozaki, Shingo Shimozaki, Norio Yamamoto, Takahiro Domoto, Hideji Nishida, Katsuhiro Hayashi, Hiroaki Kimura, Akihiko Takeuchi, Shinji Miwa, Shinji Miwa, Shinji Miwa, Kentaro Igarashi, Takashi Kato, Yu Aoki, Takashi Higuchi, Mayumi Hirose, Robert M. Hoffman, Robert M. Hoffman, Toshinari Minamoto, Hiroyuki Tsuchiya
Oncotarget   7 77038-77051   Jan 2016   [Refereed]
Development of innovative more effective therapy is required for refractory osteosarcoma patients. We previously established that glycogen synthase kinase-3β (GSK- 3β) is a therapeutic target in various cancer types. In the present study, we explo...
Ayako Kitano, Ayako Kitano, Takeo Shimasaki, Takeo Shimasaki, Takeo Shimasaki, Yuri Chikano, Yuri Chikano, Mitsutoshi Nakada, Mayumi Hirose, Tomomi Higashi, Tomomi Higashi, Yasuhito Ishigaki, Yoshio Endo, Takahisa Takino, Hiroshi Sato, Yoshimichi Sai, Ken ichi Miyamoto, Yoshiharu Motoo, Kazuyuki Kawakami, Toshinari Minamoto
PLoS ONE   8    Feb 2013   [Refereed]
Background and Purpose: The major obstacles to treatment of pancreatic cancer are the highly invasive capacity and resistance to chemo- and radiotherapy. Glycogen synthase kinase 3β (GSK3β) regulates multiple cellular pathways and is implicated in...
Jingjing Duan, Tatsuya Sugawara, Mayumi Hirose, Kazuhiko Aida, Shota Sakai, Aoi Fujii, Takashi Hirata
Experimental Dermatology   21 448-452   Jun 2012   [Refereed]
Sphingolipids are ubiquitous in eukaryotic organisms and are significant components in foods. It has been reported that treatment with sphingolipids prevents colon cancer, improves skin barrier function and suppresses inflammatory responses. Howev...
Mayumi Hirose, Ryuji Matsumura, Kaori Sato, Toshiyuki Murai, Hiroto Kawashima
Biochemical and Biophysical Research Communications   414 437-442   Oct 2011   [Refereed]
Ligands for L-selectin, a leukocyte adhesion molecule, are expressed in high endothelial venules (HEVs) in lymph nodes and extravascular tissues, such as renal tubules. Here, we report that the binding of L-selectin to its vascular and extravascul...
Ari Hashimoto, Ari Hashimoto, Shigeru Hashimoto, Shigeru Hashimoto, Ryo Ando, Kosuke Noda, Eiji Ogawa, Eiji Ogawa, Eiji Ogawa, Hirokazu Kotani, Hirokazu Kotani, Mayumi Hirose, Toshi Menju, Toshi Menju, Masaki Morishige, Masaki Morishige, Toshiaki Manabe, Yoshinobu Toda, Susumu Ishida, Hisataka Sabe, Hisataka Sabe
PLoS ONE   6    Aug 2011   [Refereed]
Angiogenesis and cancer invasiveness greatly contribute to cancer malignancy. Arf6 and its effector, AMAP1, are frequently overexpressed in breast cancer, and constitute a central pathway to induce the invasion and metastasis. In this pathway, Arf...

Association Memberships


Research Grants & Projects

Cell migration and Morphogenesis