論文

査読有り 招待有り
2017年8月

Production of Valuable Lipophilic Compounds by Using Three Types of Interface Bioprocesses: Solid-Liquid Interface Bioreactor, Liquid-Liquid Interface Bioreactor, and Extractive Liquid-Surface Immobilization System

JOURNAL OF OLEO SCIENCE
  • Shinobu Oda

66
8
開始ページ
815
終了ページ
831
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.5650/jos.ess16240
出版者・発行元
JAPAN OIL CHEMISTS SOC

Bioconversions such as enzymatic and microbial transformations are attractive alternatives to organic synthesis because of practical advantages such as resource conservation, energy efficiency, and environmentally harmonic properties. In addition, the production of secondary metabolites through microbial fermentation is also useful for manufacturing pharmaceuticals, agricultural chemicals, and aroma compounds. For microbial production of useful chemicals, the authors have developed three unique interfacial bioprocesses: a solid liquid interface bioreactor (S/L-IBR), a liquid liquid interface bioreactor (L/L-IBR), and an extractive liquid-surface immobilization (Ext-LSI) system. The S/L-IBR comprises a hydrophobic organic solvent (upper phase), a microbial film (middle phase), and a hydrophilic gel such as an agar plate (lower phase); the L/L-IBR and the Ext-LSI consist of a hydrophobic organic solvent (upper phase), a fungal mat with ballooned microspheres (middle phase), and a liquid medium (lower phase). All three systems have unique and practically important characteristics such as utilization of living cells, high concentration of lipophilic substrates/products in an organic phase, no requirement for aeration and agitation, efficient supply of oxygen, easy recovery of product, high regio- and stereoselectivity, and wide versatility. This paper reviews the principle, construction, characteristics, and application of these interfacial systems for producing lipophilic compounds such as useful aroma compounds, citronellol-related compounds, (beta-caryophyllene oxide, and 6-penty-alpha-pyrone.

Web of Science ® 被引用回数 : 4

リンク情報
DOI
https://doi.org/10.5650/jos.ess16240
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000407092500003&DestApp=WOS_CPL
ID情報
  • DOI : 10.5650/jos.ess16240
  • ISSN : 1345-8957
  • eISSN : 1347-3352
  • Web of Science ID : WOS:000407092500003

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