2018年4月17日
Enantioseparation of Sulfoxides and Nitriles by Inclusion Crystallization with Chiral Organic Salts Based on l-Phenylalanine
European Journal of Organic Chemistry
- ,
- ,
- ,
- 巻
- 2018
- 号
- 14
- 開始ページ
- 1726
- 終了ページ
- 1729
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1002/ejoc.201800003
- 出版者・発行元
- Wiley-VCH Verlag
Enantioselective inclusion of aromatic sulfoxides and nitriles was achieved in a host framework created by organic salts comprising achiral benzoic acids and a chiral primary amine (1a) derived from l-phenylalanine. Tuning of the combined achiral acid component successfully changed the chiral recognition ability of the organic salts. The guest molecules were hydrogen-bonded to form three-component inclusion crystals, and the enantiomers of nitriles and sulfoxides were separated with high selectivity up to 92 and 98 % ee. As far as we know, this is the first example of the enantioseparation of non-functionalized aromatic nitriles.
- リンク情報
- ID情報
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- DOI : 10.1002/ejoc.201800003
- ISSN : 1099-0690
- ISSN : 1434-193X
- ORCIDのPut Code : 55398501
- SCOPUS ID : 85045659514
- Web of Science ID : WOS:000430286900013