SASAKI Tsutomu Last updated: Aug 28, 2019 at 21:41
Name
SASAKI Tsutomu Affiliation
Kyoto University Section
Graduate School of Agriculture Division of Food Science and Biotechnology Job title
Associate Professor Degree
Doctor of Philosophy (Ph.D.)(University of Virginia) ORCID ID
0000-0001-8041-1915
Academic & Professional Experience
Apr 2013
Associate Professor, Gunma University
Education
-
2007
Neuroscience, Neuroscience Graduate Program, University of Virginia
Awards & Honors
2002
Crutchfield, Gage and Thomson Award
2013
JES Young Investigator Award
Published Papers
Tsutomu Sasaki, Rika Numano, Hiromi Yokota-Hashimoto, Sho Matsui, Naobumi Kimura, Hideyuki Takeuchi, Tadahiro Kitamura
Molecular Brain 11(1) 28 May 2018 [Refereed]
Matsui S, Sasaki T*, Kohno D, Yaku K, Inutsuka A, Yokota-Hashimoto H, Kikuchi O, Suga T, Kobayashi M, Yamanaka A, Harada A, Nakagawa T, Onaka T, Kitamura T.
Nature Communications Nov 2018 [Refereed]
Takayoshi Suga, Osamu Kikuchi, Masaki Kobayashi, Sho Matsui, Hiromi Yokota-Hashimoto, Eri Wada, Daisuke Kohno, Tsutomu Sasaki, Kazusane Takeuchi, Satoru Kakizaki, Masanobu Yamada, Tadahiro Kitamura
Molecular Metabolism 19 1-12 Jan 2019 [Refereed]
Aging Cell Jun 2018 [Refereed]
Tsutomu Sasaki
Nutrients 9(10) 1151 Oct 2017 [Refereed]
Fukunaka, Ayako; Fukada, Toshiyuki; Bhin, Jinhyuk; Suzuki, Luka; Tsuzuki, Takamasa; Takamine, Yuri; Bin, Bum-Ho; Yoshihara, Toshinori; Ichinoseki-Sekine, Noriko; Naito, Hisashi; Miyatsuka, Takeshi; Takamiya, Shinzaburo; Sasaki, Tsutomu; Inagaki, Takeshi; Kitamura, Tadahiro; Kajimura, Shingo; Watada, Hirotaka; Fujitani, Yoshio
PLOS GENETICS 13(8) e1006950 2017
Ishimaru, Yoshiro; Kozuka, Chisayo; Nakajima, Kenichiro; Sasaki, Tsutomu
JOURNAL OF PHYSIOLOGICAL SCIENCES 67(1) 83-95 2017
Sasaki, Tsutomu; Matsui, Sho; Kitamura, Tadahiro
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 17(7) 1081 2016
Sasaki, Tsutomu; Kuroko, Mitsutaka; Sekine, Sawako; Matsui, Sho; Kikuchi, Osamu; Susanti, Vina Yanti; Kobayashi, Masaki; Tanaka, Yoshinori; Yuasa, Tomoyuki; Kitamura, Tadahiro
ENDOCRINE JOURNAL 62(9) 787-796 2015
Sasaki, Tsutomu; Kinoshita, Yoshihiro; Matsui, Sho; Kakuta, Shigeru; Yokota-Hashimoto, Hiromi; Kinoshita, Kuni; Iwasaki, Yusaku; Kinoshita, Toshio; Yada, Toshihiko; Amano, Naoji; Kitamura, Tadahiro
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY 309(5) R561-R575 2015
Sasaki, Tsutomu
FRONTIERS IN ENDOCRINOLOGY 6 109 2015
Kohno, Daisuke; Lee, Syann; Harper, Matthew J.; Kim, Ki Woo; Sone, Hideyuki; Sasaki, Tsutomu; Kitamura, Tadahiro; Fan, Guoping; Elmquist, Joel K.
JOURNAL OF NEUROSCIENCE 34(46) 15288-15296 2014
Susanti, Vina Yanti; Sasaki, Tsutomu; Yokota-Hashimoto, Hiromi; Matsui, Sho; Lee, Yong-Soo; Kikuchi, Osamu; Shimpuku, Mayumi; Kim, Hye-Jin; Kobayashi, Masaki; Kitamura, Tadahiro
OBESITY 22(10) 2115-2119 2014
Yoshino, Satoshi; Satoh, Tetsurou; Yamada, Masanobu; Hashimoto, Koshi; Tomaru, Takuya; Katano-Toki, Akiko; Kakizaki, Satoru; Okada, Shuichi; Shimizu, Hiroyuki; Ozawa, Atsushi; Tuchiya, Takafumi; Ikota, Hayato; Nakazato, Yoichi; Mori, Munemasa; Matozaki, Takashi; Sasaki, Tsutomu; Kitamura, Tadahiro; Mori, Masatomo
ENDOCRINOLOGY 155(9) 3459-3472 2014
Sasaki, Tsutomu; Kikuchi, Osamu; Shimpuku, Mayumi; Susanti, Vina Yanti; Yokota-Hashimoto, Hiromi; Taguchi, Ryo; Shibusawa, Nobuyuki; Sato, Takashi; Tang, Lijun; Amano, Kosuke; Kitazumi, Tomoya; Kuroko, Mitsutaka; Fujita, Yuki; Maruyama, Jun; Lee, Yong-soo; Kobayashi, Masaki; Nakagawa, Takashi; Minokoshi, Yasuhiko; Harada, Akihiro; Yamada, Masanobu; Kitamura, Tadahiro
DIABETOLOGIA 57(4) 819-831 2014
Lee, Yong-Soo; Kobayashi, Masaki; Kikuchi, Osamu; Sasaki, Tsutomu; Yokota-Hashimoto, Hiromi; Susanti, Vina Yanti; Kitamura, Yukari Ido; Kitamura, Tadahiro
ENDOCRINE JOURNAL 61(1) 85-90 2014
Miglitol prevents diet-induced obesity by stimulating brown adipose tissue and energy expenditure independent of preventing the digestion of carbohydrates
Sasaki, Tsutomu; Shimpuku, Mayumi; Kitazumi, Tomoya; Hiraga, Haruna; Nakagawa, Yuko; Shibata, Hiroshi; Okamatsu-Ogura, Yuko; Kikuchi, Osamu; Kim, Hye-jin; Fujita, Yuki; Maruyama, Jun; Susanti, Vina Yanti; Yokota-Hashimoto, Hiromi; Kobayashi, Masaki; Saito, Masayuki; Kitamura, Tadahiro
ENDOCRINE JOURNAL 60(10) 1117-1129 2013
Syamsunarno, Mas Rizky A. A.; Iso, Tatsuya; Hanaoka, Hirofumi; Yamaguchi, Aiko; Obokata, Masaru; Koitabashi, Norimichi; Goto, Kosaku; Hishiki, Takako; Nagahata, Yoshiko; Matsui, Hiroki; Sano, Motoaki; Kobayashi, Masaki; Kikuchi, Osamu; Sasaki, Tsutomu; Maeda, Kazuhisa; Murakami, Masami; Kitamura, Tadahiro; Suematsu, Makoto; Tsushima, Yoshito; Endo, Keigo; Hotamisligil, Goekhan S.; Kurabayashi, Masahiko
PLOS ONE 8(11) e79386 2013
Lee, Y. -S.; Sasaki, T.; Kobayashi, M.; Kikuchi, O.; Kim, H. -J.; Yokota-Hashimoto, H.; Shimpuku, M.; Susanti, V. -Y.; Ido-Kitamura, Y.; Kimura, K.; Inoue, H.; Tanaka-Okamoto, M.; Ishizaki, H.; Miyoshi, J.; Ohya, S.; Tanaka, Y.; Kitajima, S.; Kitamura, T.
DIABETOLOGIA 56(6) 1383-1393 2013
Masubuchi, Yosuke; Nakagawa, Yuko; Ma, Jinhui; Sasaki, Tsutomu; Kitamura, Tadahiro; Yamamoto, Yoritsuna; Kurose, Hitoshi; Kojima, Itaru; Shibata, Hiroshi
PLOS ONE 8(1) e54500 2013
Hepatic FoxO1 integrates glucose utilization and lipid synthesis through regulation of Chrebp O-glycosylation.
Ido-Kitamura Y, Sasaki T, Kobayashi M, Kim HJ, Lee YS, Kikuchi O, Yokota-Hashimoto H, Iizuka K, Accili D, Kitamura T.
PLoS One 7(10) e47231 2012
Overexpression of FoxO1 in the Hypothalamus and Pancreas Causes Obesity and Glucose Intolerance.
Kim HJ, Kobayashi M, Sasaki T, Kikuchi O, Amano K, Kitazumi T, Lee YS, Yokota-Hashimoto H, Susanti VY, Kitamura YI, Nakae J, Kitamura T
Endocrinology 2012
FoxO1 as a Double-edged Sword in the Pancreas: Analysis of Pancreas and β Cell-specific FoxO1 Knockout Mice.
Kobayashi M, Kikuchi O, Sasaki T, Kim HJ, Yokota-Hashimoto H, Lee YS, Amano K, Kitazumi T, Susanti VY, Kitamura YI, Kitamura T
Am J Physiol Endocrinol Metab 2012
FoxO1 Gain of Function in the Pancreas Causes Glucose Intolerance, Polycystic Pancreas, and Islet Hypervascularization.
Kikuchi O, Kobayashi M, Amano K, Sasaki T, Kitazumi T, Kim HJ, Lee YS, Yokota-Hashimoto H, Kitamura YI, Kitamura T
PLoS One 7(2) e32249 2012
Necdin controls foxo1 acetylation in hypothalamic arcuate neurons to modulate the thyroid axis.
Hasegawa K, Kawahara T, Fujiwara K, Shimpuku M, Sasaki T, Kitamura T, Yoshikawa K.
Journal of Neuroscience 32(16) 5562-72 2012
Genetic Defect in Phospholipase C{delta}1 Protects Mice From Obesity by Regulating Thermogenesis and Adipogenesis.
Hirata M, Suzuki M, Ishii R, Satow R, Uchida T, Kitazumi T, Sasaki T, Kitamura T, Yamaguchi H, Nakamura Y, Fukami K.
Diabetes 60(7) 1926-37 2011
Roles of FoxO1 and Sirt1 in the central regulation of food intake.
Sasaki T, Kitamura T.
Endocrine Journal 57(11) 939-46 2010
Induction of hypothalamic Sirt1 leads to cessation of feeding via agouti-related peptide.
Sasaki T, Kim HJ, Kobayashi M, Kitamura YI, Yokota-Hashimoto H, Shiuchi T, Minokoshi Y, Kitamura T.
Endocrinology 151(6) 2556-66 2010
Regulation of pancreatic juxtaductal endocrine cell formation by FoxO1.
Kitamura T, Kitamura YI, Kobayashi M, Kikuchi O, Sasaki T, Depinho RA, Accili D.
Molecular and Cellular Biology Epub ahead of print 2009
Phosphorylation regulates SIRT1 function.
Sasaki T, Maier B, Koclega KD, Chruszcz M, Gluba W, Stukenberg PT, Minor W, Scrable H.
PLoS One 3 e4020 2008
Identification of the deleted in liver cancer 1 gene, DLC1, as a candidate meningioma tumor suppressor.
Hankins GR, Sasaki T, Lieu AS, Saulle D, Karimi K, Li JZ, Helm GA.
Neurosurgery 63 771-80 2008
Progressive loss of SIRT1 with cell cycle withdrawal.
Sasaki T, Maier B, Bartke A, Scrable H.
Aging Cell 5 413-422 2006
DeltaNp53 or p44: priming the p53 pump.
Scrable H, Sasaki T, Maier B. DeltaNp53 or p44: priming the p53 pump. (Int J Biochem Cell Biol, 37: 913-919, 2005)
international journal of biochemistry & cell biology 37 913-919 2005
Comparison of gene expression profiles between frozen original meningiomas and primary cultures of the meningiomas by GeneChip.
Sasaki T, Hankins GR, Helm GA.
Neurosurgery 52 892-899 2003
Osteogenic potential of five different recombinant human bone morphogenetic protein (BMP) vectors in rats.
Li JZ, Li H, Sasaki T, Holman D, Beres B, Dumont RJ, Pittman DD, Hankins GR, Helm GA.
Gene Therapy 10 1735-1743 2003
Major Vault Protein/Lung resistance-related protein (MVP/LRP) expression in nervous system tumors.
Sasaki T, Hankins GR, Helm GA.
Brain Tumor Pathology 19 59-62 2002
Ectopic Osteogenesis Using Adenoviral Bone Morphogenetic Protein (BMP)-4 and BMP-6 Gene Transfer.
Jane JA Jr, Dunford BA, Kron A, Pittman DD, Sasaki T, Li JZ, Li H, Alden TD, Dayoub H, Hankins GR, Kallmes DF, Helm GA.
Molecular Therapy 6 464-470 2002
Expression of survivin, inhibitor of apoptosis protein, in tumors of the nervous system.
Sasaki T, Lopes MBS, Hankins GR, Helm GA.
Acta Neuropathologica (Berlin) 104 105-109 2002
Cavernous angioma of the internal acoustic meatus--case report.
Sasaki T, Sasaki T, Okamoto K, Ishida T, Kirino T.
Neurologia-medico chirurgica (Tokyo) 39 847-851 1999
Iwakoshi-Ukena, Eiko; Shikano, Kenshiro; Kondo, Kunihiro; Taniuchi, Shusuke; Furumitsu, Megumi; Ochi, Yuta; Sasaki, Tsutomu; Okamoto, Shiki; Bentley, George E.; Kriegsfeld, Lance J.; Minokoshi, Yasuhiko; Ukena, Kazuyoshi
ELIFE 6 e28527 2017 [Refereed]
Sasaki, Tsutomu; Hiraga, Haruna; Yokota-Hashimoto, Hiromi; Kitamura, Tadahiro
ENDOCRINE JOURNAL 62(5) 469-473 2015 [Refereed]
Sasaki, Tsutomu; Yasoshima, Yasunobu; Matsui, Sho; Yokota-Hashimoto, Hiromi; Kobayashi, Masaki; Kitamura, Tadahiro
APPETITE 118 120-128 2017 [Refereed]
Usui, Taro; Kajita, Kazuo; Kajita, Toshiko; Mori, Ichiro; Hanamoto, Takayuki; Ikeda, Takahide; Okada, Hideyuki; Taguchi, Koichiro; Kitada, Yoshihiko; Morita, Hiroyuki; Sasaki, Tsutomu; Kitamura, Tadahiro; Sato, Takashi; Kojima, Itaru; Ishizuka, Tatsuo
FEBS LETTERS 588(10) 1935-1941 2014 [Refereed]
Research Grants & Projects
Role of hypothalamic Sirt1 in the regulation of energy metabolism.
Grant-in-Aid for Scientific Research
Project Year: 2007
