Kentaro Yoshimura

Profile Information

Affiliation: University of Yamanashi

Degree: 博士（医学）(大阪大学)

Researcher number: 70516921
J-GLOBAL ID: 200901065123754320
researchmap Member ID: 6000018038

External link: http://hh-bd.link/

研究課題

・アンビエント質量分析装置およびデータ解析手法の開発

・メタボロミクスを用いた各種生命現象の機序解明

・質量分析を基盤とした新規診断技術開発

Research Interests

Major Research Areas

Research History

Oct, 2023 - Present

University of Yamanashi
Apr, 2022 - Present

University of Yamanashi
Dec, 2019 - Mar, 2022

University of Yamanashi
Oct, 2013 - Dec, 2019

University of Yamanashi
Mar, 2008 - Sep, 2013

University of Yamanashi
Apr, 2007 - Feb, 2008

Graduate School of Medicine, Osaka University

Awards

May, 2021

2021年度日本質量分析学会会誌賞, Probe Electrospray Ionization (PESI) and Its Modified Versions: Dipping PESI (dPESI), Sheath-Flow PESI (sfPESI) and Adjustable sfPESI (ad-sfPESI), 日本質量分析学会

平岡賢三, 有屋田修, Dilshadbek T. Usmanov, Lee C. Chen, 二宮啓, 吉村健太郎, 竹田扇, Zhang Yu, Mridul K. Mandal, 和田博史, Stephanie Rankin-Turner, 野並浩
Jul, 2020

山梨大学優秀教員奨励制度特別表彰, 山梨大学

吉村健太郎
Jul, 2019

Shimadzu Global Innovation Summit 2019, Excellent Poster Award, Probe electrospray ionization-mass spectrometry serving two ends: Clinical diagnosis and elucidation of molecular mechanism, Shimadzu Corporation

吉村健太郎
May, 2014

第62回質量分析総合討論会ベストプレゼンテーション賞、最優秀賞, 探針エレクトロスプレーイオン化法と汎用帰納的推論機械を用いた診断システムの開発と応用, The Mass Spectrometry Society of Japan

吉村健太郎
Sep, 2013

第61回質量分析総合討論会ベストプレゼンテーション賞, 学習機械を用いた質量分析型がん診断装置の開発, The Mass Spectrometry Society of Japan

吉村健太郎
Jul, 2012

山梨大学優秀職員奨励制度特別表彰, 山梨大学

吉村健太郎
Jul, 2012

平成24年度戦略的プロジェクト経費（若手研究者等の表彰）, 山梨大学

吉村健太郎
Jun, 2010

第58回質量分析総合討論会/第1回アジア・オセアニア質量分析会議優秀ポスター賞, 探針エレクトロスプレーイオン化法を用いた生体マススペクトル解析, The Mass Spectrometry Society of Japan

吉村健太郎

Papers

Ambient Mass Spectrometry and Machine Learning-Based Diagnosis System for Acute Coronary Syndrome.

Que N N Tran, Takeshi Moriguchi, Masateru Ueno, Tomohiko Iwano, Kentaro Yoshimura

Mass spectrometry (Tokyo, Japan), 13(1) A0147, Jul, 2024 Peer-reviewedLast author
Automated sample preparation for electrospray ionization mass spectrometry based on CLOCK-controlled autonomous centrifugal microfluidics

Masahiro Futami, Hiroki Naito, Satoshi Ninomiya, Lee Chuin Chen, Tomohiko Iwano, Kentaro Yoshimura, Yoshiaki Ukita

Biomedical Microdevices, 26(2) 1-9, Apr, 2024 Peer-reviewed
New Diagnostic Modality Combining Mass Spectrometry and Machine Learning for the Discrimination of Malignant Intraductal Papillary Mucinous Neoplasms

Sho Kiritani, Tomohiko Iwano, Kentaro Yoshimura, Ryo Saito, Takashi Nakayama, Daisuke Yamamoto, Hiroyuki Hakoda, Genki Watanabe, Nobuhisa Akamatsu, Junichi Arita …

Annals of Surgical Oncology, Jan 8, 2023 Peer-reviewed
Probe electrospray ionization mass spectrometry‐based rapid diagnosis of liver tumors

Hiroyuki Hakoda, Sho Kiritani, Takashi Kokudo, Kentaro Yoshimura, Tomohiko Iwano, Meguri Tanimoto, Takeaki Ishizawa, Junichi Arita, Nobuhisa Akamatsu, Junichi Kaneko …

Journal of Gastroenterology and Hepatology, Aug 16, 2022 Peer-reviewed
Association of allele-specific methylation of the ASNS gene with asparaginase sensitivity and prognosis in T-ALL.

Koshi Akahane, Shunsuke Kimura, Kunio Miyake, Atsushi Watanabe, Keiko Kagami, Kentaro Yoshimura, Tamao Shinohara, Daisuke Harama, Shin Kasai, Kumiko Goi …

Blood advances, 6(1) 212-224, Jan 11, 2022 Peer-reviewed
New strategy for evaluating pancreatic tissue specimens from endoscopic ultrasound-guided fine needle aspiration and surgery.

Seiichiro Fukuhara, Eisuke Iwasaki, Tomohiko Iwano, Yujiro Machida, Hiroki Tamagawa, Shintaro Kawasaki, Takashi Seino, Takahiro Yokose, Yutaka Endo, Kentaro Yoshimura …

JGH open : an open access journal of gastroenterology and hepatology, 5(8) 953-958, Aug, 2021 Peer-reviewed
Diagnostic significance of plasma lipid markers and machine learning-based algorithm for gastric cancer.

Ryo Saito, Kentaro Yoshimura, Katsutoshi Shoda, Shinji Furuya, Hidenori Akaike, Yoshihiko Kawaguchi, Tasuku Murata, Koretsugu Ogata, Tomohiko Iwano, Sen Takeda …

Oncology letters, 21(5) 405-405, May, 2021 Peer-reviewed
A new rapid diagnostic system with ambient mass spectrometry and machine learning for colorectal liver metastasis.

Sho Kiritani, Kentaro Yoshimura, Junichi Arita, Takashi Kokudo, Hiroyuki Hakoda, Meguri Tanimoto, Takeaki Ishizawa, Nobuhisa Akamatsu, Junichi Kaneko, Sen Takeda …

BMC cancer, 21(1) 262-262, Mar 10, 2021 Peer-reviewed
Miniaturized String Sampling Probe and Electrospray Extraction/Ionization within the Ion Inlet Tube for Mass Spectrometric Endoscopy.

Lee Chuin Chen, Tomohiko Iwano, Satoshi Ninomiya, Takayuki Koike, Yoshihisa Tanaka, Kentaro Yoshimura

Journal of the American Society for Mass Spectrometry, 32(2) 606-610, Feb 3, 2021 Peer-reviewedCorresponding author
Prediction of Pathological and Radiological Nature of Glioma by Mass Spectrometry Combined With Machine Learning

Keiko Suzuki, Kentaro Yoshimura, Tomoyuki Kawataki, Mitsuto Hanihara, Sen Takeda, Hiroyuki Kinouchi

Neurosurgery Open, 2(1), Jan 25, 2021 Peer-reviewed
High-performance Collective Biomarker from Liquid Biopsy for Diagnosis of Pancreatic Cancer Based on Mass Spectrometry and Machine Learning

Tomohiko Iwano, Kentaro Yoshimura, Genki Watanabe, Ryo Saito, Sho Kiritani, Hiromichi Kawaida, Takeshi Moriguchi, Tasuku Murata, Koretsugu Ogata, Daisuke Ichikawa …

Journal of Cancer, 12(24) 7477-7487, 2021 Peer-reviewed
Probe Electrospray Ionization (PESI) and Its Modified Versions: Dipping PESI (dPESI), Sheath-Flow PESI (sfPESI) and Adjustable sfPESI (ad-sfPESI).

Kenzo Hiraoka, Osamu Ariyada, Dilshadbek T Usmanov, Lee C Chen, Satoshi Ninomiya, Kentaro Yoshimura, Sen Takeda, Zhang Yu, Mridul K Mandal, Hiroshi Wada …

Mass spectrometry (Tokyo, Japan), 9(1) A0092-21, Dec 4, 2020 Peer-reviewed
Rapid automated diagnosis of primary hepatic tumour by mass spectrometry and artificial intelligence.

Silvia Giordano, Sen Takeda, Matteo Donadon, Hidekazu Saiki, Laura Brunelli, Roberta Pastorelli, Matteo Cimino, Cristiana Soldani, Barbara Franceschini, Luca Di Tommaso …

Liver international : official journal of the International Association for the Study of the Liver, 40(12) 3117-3124, Dec, 2020 Peer-reviewed
Breast cancer diagnosis based on lipid profiling by probe electrospray ionization mass spectrometry

T Iwano, K Yoshimura, S Inoue, T Odate, K Ogata, S Funatsu, H Tanihata, T Kondo, D Ichikawa, S Takeda

The British journal of surgery, 107(6) 632-635, Apr 4, 2020 Peer-reviewed
Lipidome-based rapid diagnosis with machine learning for detection of TGF-β signalling activated area in head and neck cancer.

Hiroki Ishii, Masao Saitoh, Kaname Sakamoto, Kei Sakamoto, Daisuke Saigusa, Hirotake Kasai, Kei Ashizawa, Keiji Miyazawa, Sen Takeda, Keisuke Masuyama …

British journal of cancer, 122(7) 995-1004, Mar, 2020 Peer-reviewedLast authorCorresponding author
Sample Preparation for Probe Electrospray Ionization Mass Spectrometry.

Sen Takeda, Kentaro Yoshimura, Hiroshi Tanihata

Journal of visualized experiments : JoVE, (156), Feb 19, 2020 Peer-reviewed
Using probe electrospray ionization mass spectrometry and machine learning for detecting pancreatic cancer with high performance.

Wen Y Chung, Elon Correa, Kentaro Yoshimura, Ming-Chu Chang, Ashley Dennison, Sen Takeda, Yu-Ting Chang

American journal of translational research, 12(1) 171-179, Jan, 2020 Peer-reviewed
Real-time analysis of living animals and rapid screening of human fluid samples using remote sampling electrospray ionization mass spectrometry.

Kentaro Yoshimura, Yuki Yamada, Satoshi Ninomiya, Wen Yuan Chung, Yu-Ting Chang, Ashley Robert Dennison, Kenzo Hiraoka, Sen Takeda, Lee Chuin Chen

Journal of pharmaceutical and biomedical analysis, 172 372-378, Aug 5, 2019 Peer-reviewedLead authorCorresponding author
Ambient mass spectrometry-based detection system for tumor cells in human blood

Kaname Sakamoto, Yuichiro Fujita, Kazuaki Chikamatsu, Shota Tanaka, Sen Takeda, Keisuke Masuyama, Kentaro Yoshimura, Hiroki Ishii

Translational Cancer Research, 7(3) 758-764, Jun 1, 2018 Peer-reviewedCorresponding author
Detection of potential new biomarkers of atherosclerosis by probe electrospray ionization mass spectrometry.

Hisashi Johno, Kentaro Yoshimura, Yuki Mori, Tokuhide Kimura, Manabu Niimi, Masaki Yamada, Tetsuo Tanigawa, Jianglin Fan, Sen Takeda

Metabolomics : Official journal of the Metabolomic Society, 14(4) 38-38, Feb 27, 2018 Peer-reviewedCorresponding author

Professional Memberships

Jan, 2024 - Present

クロマトグラフィー科学会
May, 2011 - Present

THE MASS SPECTROMETRY SOCIETY OF JAPAN
Apr, 2003 - Present

日本解剖学会
Apr, 2022 - Present

The Molecular Biology Society of Japan

Industrial Property Rights

特開2024-148741 解析方法及び解析システム

岩野智彦, 吉村健太郎
特開2024-120779 鼻汁代謝物による花粉症の重症度判定法

石井裕貴, 吉村健太郎, 櫻井大樹
特許7464271号分離装置及び分離方法、並びに検査装置及び検査方法

浮田芳昭, 内藤大揮, 二宮啓, 岩野智彦, 吉村健太郎
特許7348626号生体試料の状態評価装置、システム、方法、およびプログラム

吉村健太郎, 佐藤金夫, 大舘徹, 川井将敬
特許7158642号質量分析装置及び質量分析システム

吉村健太郎, 石井裕貴, チェンリーチュイン
特許7025621号質量分析装置及び質量分析方法、並びに解析装置及び解析方法

吉村健太郎, チェンリーチュイン, 二宮啓
特許6715451号マススペクトル解析システム，方法およびプログラム

吉村健太郎, 城野悠志, 舟山慧, 川井将敬, 森優喜, 竹田扇
特許6189587号質量分析装置、及び該装置を用いた癌診断装置

出水秀明, 谷端博司, 糸井弘人, 田邉國士, 竹田扇, 吉村健太郎, 平岡賢三, チェン, リーチュイン, 堀裕和

Profile Information

Research Interests

Major Research Areas

Research History

Awards

Papers

Professional Memberships

Industrial Property Rights

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