SHIGA Hideaki

J-GLOBAL         Last updated: Dec 28, 2019 at 02:57
 
Avatar
Name
SHIGA Hideaki
Affiliation
Kanazawa Medical University
Section
School of Medicine, Department of Otolaryngology
Job title
Associate Professor
Degree
Ph.D in Medicine

Academic & Professional Experience

 
Apr 1995
   
 
Resident, Kanazawa University Hospital
 
Apr 1997
   
 
Visiting Fellow, Georgetown University Medical Center
 
Apr 2003
   
 
Research Scholar, National Institutes of Health (U.S.A.)
 
Jan 2007
   
 
Assistant Professor, Kanazawa University Hospital
 
Jun 2009
   
 
Senior Assistant Professor, Kanazawa Medical University
 
Jul 2013
   
 
Associate Professor, Kanazawa Medical University
 

Education

 
Apr 1995
 - 
Sep 1999
Division of Medicine, Graduate School, Kanazawa University
 
Apr 1989
 - 
Mar 1995
Faculty of Medicine, Kanazawa University
 

Committee Memberships

 
2011
   
 
Japanese Society of Allergology  会員
 
2011
   
 
The Japanese Association for the Study of Taste and Smell  評議員
 
2009
   
 
Japanese Society for Molecular Imaging  会員
 
2006
   
 
Association for Chemoreception Sciences  Regular member
 
2006
   
 
Japanese Rhinologic Society  会員
 
1995
   
 
The Oto-Rhino-Laryngological Society of Japan  会員
 

Awards & Honors

 
2011
Evaluation of the olfactory nerve transport function by SPECT-MRI fusion image with nasal thallium-201 administration, Molecular Imaging and Biology, [Epub ahead of print],2010.
 
Jan 2012
THE TAKASAGO AWARD FOR RESEARCH ENCOURAGEMENT, 嗅覚障害の病態研究における分子イメージングの応用
 
Jan 2000
学術論文
 

Published Papers

 
Miwa T, Ikeda K, Ishibashi T, Kobayashi M, Kondo K, Matsuwaki Y, Ogawa T, Shiga H, Suzuki M, Tsuzuki K, Furuta A, Motoo Y, Fujieda S, Kurono Y
Auris, nasus, larynx   46(5) 653-662   Oct 2019   [Refereed]
Shiga H, Okuda K, Taki J, Watanabe N, Tonami H, Kinuya S, Miwa T
International forum of allergy & rhinology      Jul 2019   [Refereed]
Harita M, Miwa T, Shiga H, Yamada K, Sugiyama E, Okabe Y, Miyake Y, Okuno T, Iritani O, Morimoto S
Geriatrics & gerontology international   19(5) 384-391   May 2019   [Refereed]
Noda T, Shiga H, Yamada K, Harita M, Nakamura Y, Ishikura T, Kumai M, Kawakami Z, Kaneko A, Hatta T, Sakata-Haga H, Shimada H, Miwa T
Chemical senses   44(5) 327-338   May 2019   [Refereed]
Gender differences and influences to olfactory nerve regeneration by ovariectomy in mice
Miwa Takaki, Yamada Kentaro, Noda Takuya, Harita Masayuki, Shiga Hideaki
CHEMICAL SENSES   43(7) E179   Sep 2018   [Refereed]
Correlation of nasal thallium migration to olfactory bulb and olfactory bulb volume in patients with olfactory impairment after upper respiratory infection
Shiga Hideaki, Taki Junichi, Okuda Koichi, Watanabe Naoto, Tonami Hisao, Kinuya Seigo, Miwa Takaki
CHEMICAL SENSES   43(4) E54   May 2018   [Refereed]
嗅覚障害診療ガイドライン
56(4) 487-556   Dec 2017   [Refereed]
嗅覚障害に対する漢方治療
33(2) 231-233   Feb 2017   [Refereed]
Shiga Hideaki;Taki Junichi;Okuda Koichi;Watanabe Naoto;Tonami Hisao;Nakagawa Hideaki;Kinuya Seigo;Miwa Takaki
Scientific reports   7(1) 1   2017   [Refereed]
:Idiopathic olfactory disorder is resistant to treatment, and the recovery time is long. This study investigated the prognostic value of the migration of nasally administered thallium-201 to the olfactory bulb (thallium migration to the OB), a mea...
Clinical value of olfactory molecular imaging
Shiga Hideaki, Miwa Takaki
CHEMICAL SENSES   41(9) E124   Nov 2016   [Refereed]
Behavioral assessment of mouse olfaction using a new experimental device
Harita Masayuki, Shiga Hideaki, Hiraba Tomoko, Nakamura Yukari, Noda Takuya, Yamada Kentaro, Ninomiya Hideaki, Miwa Takaki
CHEMICAL SENSES   41(9) E196   Nov 2016   [Refereed]
Effect of Kampo medicine Tokishakuyakusan on olfactory epithelium in olfactory impaired mice
Noda Takuya, Shiga Hideaki, Ninomiya Hideaki, Nakamura Yukari, Hiraba Tomoko, Harita Masayuki, Yamada Kentaro, Yamamoto Junpei, Miwa Takaki
CHEMICAL SENSES   41(9) E205   Nov 2016   [Refereed]
An investigation into the differences in damage of the olfactory epithelium between female and male mice after administration of methimazole
Yamada Kentaro, Shiga Hideaki, Ninomiya Hideaki, Yamamoto Jyunpei, Noda Takuya, Harita Masayuki, Nakamura Yukari, Hiraba Tomoko, Miwa Takaki
CHEMICAL SENSES   41(9) E204-E205   Nov 2016   [Refereed]
Direct transport of insulin to the olfactory bulb of mice by nasal administration
Nakamura Yukari, Shiga Hideaki, Ninomiya Hideaki, Noda Takuya, Yamada Kentaro, Harita Masayuki, Hiraba Tomoko, Yamamoto Junpei, Miwa Takaki
CHEMICAL SENSES   41(9) E252-E253   Nov 2016   [Refereed]
The relationship between olfactory dysfunction and the number of eosinophils in nasal polyp tissues in surgical cases
Hiraba Tomoko, Nakamura Yukari, Noda Takuya, Yamada Kentaro, Yamamoto Junpei, Teraguchi Kanako, Shiga Hideaki, Miwa Takaki
CHEMICAL SENSES   41(9) E262   Nov 2016   [Refereed]
Bilateral dysgeusia after head trauma
Yamamoto Junpei, Shiga Hideaki, Hiraba Tomoko, Nakamura Yukari, Harita Masayuki, Noda Takuya, Yamada Kentaro, Miwa Takaki
CHEMICAL SENSES   41(9) E282   Nov 2016   [Refereed]
Prognostic value of olfactory nerve scintigraphy by per-nasal Tl-201 administration in patients with impaired sense of smell
Taki Junichi, Shiga Hideaki, Okuda Koichi, Miwa Takaki, Inaki Anri, Kinuya Seigo
JOURNAL OF NUCLEAR MEDICINE   57    May 2016   [Refereed]
Changes in smell and taste function in the elderly
Miwa Takaki, Yamamoto Junpei, Teraguchi Kanako, Kinoshita Yuko, Ymamda Kentaro, Noda Takuya, Harita Masayuki, Shiga Hideaki, Sugiyama Eriko, Ono Kaori, Kawai Misako
CHEMICAL SENSES   40(3) 261   Mar 2015   [Refereed]
鼻粘膜接触点頭痛
107:672-673    Sep 2014
Reduced nasal transport of insulin-like growth factor-1 to the mouse cerebrum with olfactory bulb resection.
H.Shiga, M.Nagaoka, K.Washiyama, J.Yamamoto, K.Yamada, T.Noda, M.Harita, R.Amano, T.Miwa
Chemical senses.   39:595-599    Sep 2014
外傷性嗅覚障害の漢方治療成績と分子イメージング解析
53:71-72    Jul 2014
嗅覚障害に対する局所薬物療法
168:27-30    Jun 2014
がん化学療法施行患者における客観的な指標を用いた嗅覚異常の評価.
50:745-748    Jun 2014
Rapamycin downregulates thymidylate synthase and potentiates the activity of pemetrexed in non-small cell lung cancer.
(S.Kawabata), CT.Chiang, J.Tsurutani, H.Shiga, ML.Arwood, T.Komiya, JJ.Gills, RM.Memmott, PA.Dennis
Oncotarget [electronic resource]   5:1062-1070.    Feb 2014
Combinations of two odorants of smell identification test for screening of olfactory impairment.
H.Shiga, J.Yamamoto, M.Kitamura, H.Nakagawa, T.Matsubasa, A.Seo, T.Miwa
Auris, nasus, larynx.   41:523-527    2014
耳鼻咽喉科診療で用いる漢方薬 加味帰脾湯
29:2034-2036    Dec 2013
Post-traumatic olfactory impairment
H.Shiga
45:278-281    Jul 2013
Assessment of olfactory nerve by SPECT-MRI image with nasal thallium-201 administration in patients with olfactory impairments in comparison to healthy volunteers.
H.Shiga, J.Taki, K.Washiyama, J.Yamamoto, S.Kinase, K.Okuda, S.Kinuya, N.Watanabe, H.Tonami, K.Koshida, R.Amano, M.Furukawa, T.Miwa
PloS one   8:e57671;1-8    Feb 2013
Olefactory nerve transport of macromolecular drugs to the brain -A problem in olfactory impaired patients-
H.Shiga, J.Yamamoto, T.Miwa
55(補1) :15-19    Aug 2012
Internal dosimetry for nasal thallium-201 administration.
(S.Kinase), K.Washiyama, H.Shiga, J.Taki, Y.Nakanishi, K.Koshida, T.Miwa, S.Kinuya, R.Amano
KEK Proceedings   7:35-40    2012
Olfactory nerve scintigraphy in patients with impaired sense of smell by per-nasal Tl-201 administration
Taki Junichi, Shiga Hideaki, Inaki Anri, Wakabayashi Hiroshi, Washiyama Kohshin, Miwa Takaki, Kinuya Seigo
JOURNAL OF NUCLEAR MEDICINE   52    May 2011   [Refereed]
Biological safety of nasal thallium-201 administration: a preclinical study for olfacto-scintigraphy
(K.Washiyama), H.Shiga, K.Hirota, A.Tsuchida, J.Yamamoto, S.Yagi, T.Yoshizaki, M.Furukawa, R.Amano, T.Miwa
Journal of radiation research   Epub ahead of print    May 2011
Evaluation of the olfactory nerve transport function by SPECT-MRI fusion image with nasal thallium-201 administration
H.Shiga, J.Taki, M.Yamada, K.Washiyama, R.Amano, Y.Matsuura, O.Matsui, S.Tatsutomi, S.Yagi, A.Tsuchida, T.Yoshizaki, M.Furukawa, S.Kinuya, T.Miwa
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging   13:1262-1266    Dec 2010
A case of recurrent frontal sinusitis -The usefulness of Mini-Trephine-
K.Yamada, H.Shiga, J.Yamamoto, T.Miwa
53:327-330    Oct 2010
嗅覚同定機能測定器具
26:855-858    Jun 2010
Olfactory nerve scintigraphy in normal volunteer by per-nasal Tl-201 administration
Taki Junichi, Yamada Masato, Shiga Hideaki, Miwa Takaki, Washiyama Kohshin, Wakabayashi Hiroshi, Inaki Anri, Kinuya Seigo
JOURNAL OF NUCLEAR MEDICINE   51    May 2010   [Refereed]
漢方薬の取り入れ方のコツ 嗅覚障害
26:592-594    Apr 2010
嗅神経画像評価のための201Tlオルファクトシンチグラフィの試み
24:40-43    Apr 2010
嗅神経再生診断における分子イメージングの応用
49:72-73    Apr 2010
外来癌化学療法における嗅覚の変化
653-654    Dec 2009
Use of thallium transport to visualize functional olfactory nerve regeneration in vivo
H.Shiga, K.Washiyama, K.Hirota, R.Amano, M.Furukawa, T.Miwa
Rhinology   47:460-464    Dec 2009
Usefulness of curry odorant of odor stick identification test for Japanese in olfactory impairment screening
H.Shiga, H.Toda, T.Kobayakawa, S.Saito, K.Hirota, T.Tsukatani, M.Furukawa, T.Miwa
Acta oto-laryngologica.   129(Suppl.562):91-94    Jun 2009
Olfactory nerve regeneration and molecular imaging
H.Shiga, T.Miwa
The Japanese journal of taste and smell research.   16 (1) : 11-15 11-15   Apr 2009
Odor detection ability and thallium-201 transport in the olfactory nerve of traumatic olfactory-impaired mice.
H.Shiga, Y.Kinoshita, K.Washiyama, R.Amano, K.Hirota, T.Tsukatani, M.Furukawa, T.Miwa
Chemical senses.   33: 633-637    Sep 2008
Thallium transport and the evaluation of olfactory nerve connectivity between the nasal cavity and olfactory bulb.
(Y.Kinoshita), H.Shiga, K.Washiyama, D.Ogawa, R.Amano, M.Ito, T.Tsukatani, M.Furukawa, T.Miwa
Chemical senses.   33: 73-78    Jan 2008
カレー1臭による嗅覚スクリーニングの可能性.
14 (3) : 517-518    Dec 2007
人間ドックにおけるスティック型嗅覚検査法 (OSIT)による嗅覚障害スクリーニングの検討.
110(8):586-591    Aug 2007
Prognostic value of p53, glutathione S-transferase π, and thymidylate synthase for neoadjuvant cisplatin-based chemotherapy in head and neck cancer.
H.Shiga, EI.Heath, AA.Rasmussen, B.Trock, PG.Johnston, AA.Forastiere, M.Langmacher, A.Baylor, M.Lee, KJ.Cullen
Clinical cancer research : an official journal of the American Association for Cancer Research.   5:4097-4104 4097-4104   1999
Patient with primary tonsillar and gastric syphilis.
(T.Ishimaru), Y.Mizuno, H.Shiga, I.Nagayama, M.Furukawa
The Journal of laryngology and otology   111:766-768 766-768   1997
H.Shiga, T.Miwa
Nihon Bika Gakkai Kaishi (Japanese Journal of Rhinology)   54(1) 47-51   2015
An injury to the olfactory nerve between the olfactory epithelium and olfactory bulb cannot be easily visualized even with high-resolution magnetic resonance imaging (MRI). Previously, our group has reported that nasally administered thallium-203 ...

Books etc

 
Innovative imaging of olfactory nerve connectivity “Thallium-201 olfacto-scintigraphy”
H.Shiga, T.Miwa
Nova Science Publishers   Jan 2011   

Conference Activities & Talks

 
経鼻的投与したIGF-1の脳内神経芽細胞遊走へ及ぼす影響
中村 有加里, 志賀 英明, 二宮 英明, 坂田 ひろみ, 八田 稔久, 三輪 高喜
日本耳鼻咽喉科学会会報   Apr 2019   
オルファクトシンチによる感冒後異嗅症の検討
志賀 英明, 三輪 高喜
日本耳鼻咽喉科学会会報   Apr 2019   
当帰芍薬散が嗅神経の再生に及ぼす影響に関する研究
能田 拓也, 山田 健太郎, 張田 雅之, 中村 有加里, 石倉 友子, 熊井 理美, 志賀 英明, 三輪 高喜
日本耳鼻咽喉科学会会報   Apr 2019   
嗅神経性嗅覚障害における食事を利用した嗅覚刺激療法の比較研究
28 Sep 2018   
視覚障がい者スポーツにおける聴覚管理の事例検討
5 Oct 2018   
高齢者の味嗅覚の低下とサルコペニアとの関係
13 Sep 2018   
嗅上皮障害マウスにおける当帰芍薬散と神経栄養因子との関連に関する研究
24 Feb 2018   
卵巣摘出マウスにおける嗅上皮障害後の嗅上皮再生に関する研究
24 Feb 2018   
IGF-1の経鼻投与による脳内新生ニューロン移動促進効果の検討
中村 有加里, 志賀 英明, 二宮 英明, 三輪 高喜
耳鼻咽喉科免疫アレルギー   Jun 2018   
遺伝性出血性末梢血管拡張症における遺伝子検査の意義
1 Jun 2018   
IGF-1経鼻投与による嗅球への神経新生細胞到達促進の検討
31 May 2018   
嗅覚検査と画像診断 国内外の動向
志賀 英明
日本耳鼻咽喉科学会会報   Apr 2018   
鼻腔内より発生した小児炎症性筋線維芽細胞性腫瘍の一例
中村 有加里, 寺口 奏子, 志賀 英明, 山本 純平, 三輪 高喜
日本鼻科学会会誌   Sep 2017   
嗅覚障害の病態・治療研究の最前線 嗅神経性嗅覚障害の病態解明と治療への応用
山田 健太郎, 志賀 英明, 能田 拓也, 張田 雅之, 二宮 英明, 三輪 高喜
日本鼻科学会会誌   Sep 2017   
食べ方の指導による嗅覚刺激療法 鼻腔法と口腔法の比較
18 May 2017   
マウス嗅上皮障害後の再生における性差に関する研究
山田 健太郎, 張田 雅之, 能田 拓也, 志賀 英明, 三輪 高喜
日本鼻科学会会誌   Sep 2016   
嗅覚障害の病態と治療の進歩 分子イメージングで明らかとなった嗅覚障害の病態と新たな治療への展望
志賀 英明, 三輪 高喜
日本鼻科学会会誌   Sep 2016   
Prognostic value of olfactory nerve assessment with olfacto-scintigraphy in patients with olfactory disorders
H. Shiga, J.Taki, K.Okuda, N.Watanabe, H.Tonami, M.Furukawa, S.Kinuya, T.Miwa
The 37th annual meeting of the Association for Chemoreception Sciences   22 Apr 2015   
嗅覚障害における嗅神経再生と嗅球体積の検討
2 Oct 2015   
当帰芍薬散による嗅細胞再生の実験的観察
2 Oct 2015   

Research Grants & Projects

 
パーキンソン病における嗅覚障害の分子イメージング研究
Project Year: 2017 - 2020
食べ方の指導による嗅神経再生効果の画像解析研究
Project Year: 2013 - 2016
嗅神経及び腫瘍へ集積し高エネルギーを付与する原子核プローブに関する核放射化学研究
Project Year: 2011 - 2013
嗅神経経由の輸送を利用した他覚的嗅覚検査の開発
Project Year: 2009 - 2012