論文

査読有り
2015年6月

A short period of fasting before surgery conserves basal metabolism and suppresses catabolism according to indirect calorimetry performed under general anesthesia

JOURNAL OF ANESTHESIA
  • Shinichiro Yoshimura
  • ,
  • Yoshihito Fujita
  • ,
  • Hiroyuki Hirate
  • ,
  • Nobuyoshi Kusama
  • ,
  • Takafumi Azami
  • ,
  • Kazuya Sobue

29
3
開始ページ
453
終了ページ
456
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1007/s00540-014-1950-3
出版者・発行元
SPRINGER JAPAN KK

It is recommended that the period of fasting before elective surgery should be shortened to facilitate a rapid recovery by preventing catabolism. We examined the effects of a short period of fasting on metabolism by performing indirect calorimetry (IC) under general anesthesia. A prospective observational study involving 26 consecutive patients who underwent elective surgery and whose metabolism was evaluated using IC during anesthesia was conducted. The patients were divided into two groups, those who fasted for < 8 h (group S) and those who fasted for > 10 h (group L). Oxygen consumption, the volume of carbon dioxide emissions (VCO2), the respiratory quotient (RQ), resting energy expenditure (REE), and basal energy expenditure (BEE) were compared. The REE, VCO2, and RQ of group L (17.7 +/- A 2.3 kcal/kg/day, 118.5 +/- A 20.8 ml/min, and 0.71 +/- A 0.12, respectively) were significantly lower than those of group S (19.7 +/- A 2.3 kcal/kg/day, 143.6 +/- A 30.9 ml/min, and 0.81 +/- A 0.09, respectively) (P < 0.05). In group L, the relationship between REE and BEE was weaker (r (2) = 0.501) and the BEE-REE slope was less steep (REE = 0.419BEE + 509.477) than those seen in group S (r (2) = 0.749 and REE = 1.113BEE - 376.111, respectively). Our findings suggest that a short period of fasting (< 8 h) before surgery is more strongly associated with the conservation of basal metabolism.

Web of Science ® 被引用回数 : 3

リンク情報
DOI
https://doi.org/10.1007/s00540-014-1950-3
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/25398400
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000357281100022&DestApp=WOS_CPL

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