2014年6月
Propargyltrimethylsilanes as Allene Equivalents in Transition Metal-Catalyzed [5+2] Cycloadditions
ORGANIC LETTERS
- ,
- ,
- ,
- 巻
- 16
- 号
- 11
- 開始ページ
- 2923
- 終了ページ
- 2925
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1021/ol501114q
- 出版者・発行元
- AMER CHEMICAL SOC
Conventional allenes have not been effective pi-reactive 2-carbon components in many intermolecular cyclo-additions including metal-catalyzed [5 + 2] cycloadditions. We report herein that rhodium-catalyzed [5 + 2] cycloadditions of propargyltrimethylsilanes and vinylcyclopropanes provide, after in situ protodesilylation, a highly efficient route to formal allene cycloadducts. Propargyltrimethylsilanes function as safe, easily handled synthetic equivalents of gaseous allenes and hard-to-access monosubstituted allenes. In this one-flask procedure, they provide cycloadducts of what is formally addition to the more sterically encumbered allene double bond.
- リンク情報
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- DOI
- https://doi.org/10.1021/ol501114q
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000337074300036&DestApp=WOS_CPL
- URL
- http://www.scopus.com/inward/record.url?eid=2-s2.0-84902105381&partnerID=MN8TOARS
- URL
- http://orcid.org/0000-0003-2999-083X
- ID情報
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- DOI : 10.1021/ol501114q
- ISSN : 1523-7060
- eISSN : 1523-7052
- ORCIDのPut Code : 36826992
- SCOPUS ID : 84902105381
- Web of Science ID : WOS:000337074300036