2011年6月
Surgical removal of amyloid-laden lymph nodes: a possible therapeutic approach in a primary systemic AL amyloidosis patient with focal lymphadenopathy
AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS
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- 巻
- 18
- 号
- 2
- 開始ページ
- 79
- 終了ページ
- 82
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.3109/13506129.2011.560216
- 出版者・発行元
- INFORMA HEALTHCARE
We report a patient with primary systemic AL amyloidosis who suffered from remarkable bilateral cervical lymphadenopathy. Intensive chemotherapies, including two cycles of high-dose melphalan with autologous peripheral blood stem cell transplantation, were insufficiently effective for both the lymphadenopathy and amyloidogenic IgG lambda lambda-type M-protein in serum, but the patient showed complete haematological remission after extensive surgical removal of enlarged lymph nodes that had massive depositions of lambda lambda-type immunoglobulin light chain-derived amyloid. Lymphadenectomy may be a possible therapeutic approach with regard to both cosmetic and haematological aspects in primary systemic AL amyloidosis patients with focal lymphadenopathy.</.
- リンク情報
- ID情報
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- DOI : 10.3109/13506129.2011.560216
- ISSN : 1350-6129
- Web of Science ID : WOS:000290486500007