YOSHIZAWA Katsuhiko

J-GLOBAL         Last updated: Nov 4, 2018 at 21:00
 
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Name
YOSHIZAWA Katsuhiko
URL
http://www.kmu.ac.jp/indexja.shtml
Affiliation
Mukogawa Women's University
Section
School of Human Environmental Sciences
Job title
Lecturer

Research Interests

 
 

Research Areas

 

Academic & Professional Experience

 
Apr 2017
 - 
Today
Professor, Department of Food Sciences and Nutrition, School of Human Environmental Sciences, Mukogawa Women's University
 
Apr 2009
 - 
Mar 2017
Assistant Professor, Department of Pathology II, Kansai Medical University
 
Apr 2005
 - 
Mar 2009
Reseach manager, Drug Safety Laboratories, Astellas Pharmaceutical Co., Ltd.
 
Apr 2006
 - 
Mar 2009
Vistiting associate professor, Department of Pathology II, Kansai Medical University
 
Feb 2004
 - 
Mar 2005
Visiting researcher, Laboratory of Experimental Pathology, National Institutes of Environmental Health Sciences
 
Apr 2001
 - 
Mar 2004
Reseach manager, Drug Safety Laboratories, Fujisawa Pharmaceutical Co., Ltd.
 
Apr 1996
 - 
Mar 2001
Chief, Drug Safety Laboratories, Fujisawa Pharmaceutical Co., Ltd.
 
Apr 1989
 - 
Mar 1996
Reseacrher, Drug Safety Laboratories, Fujisawa Pharmaceutical Co., Ltd.
 

Education

 
 
 - 
1989
Faculty of Marine Science and Technology, Tottori University
 

Committee Memberships

 
1999
 - 
2005
Conference on Experimental Animal Histopathology  
 
2005
 - 
2008
Conference on Experimental Animal Histopathology  
 
2012
   
 
International Academy of Toxicologic Pathology  
 
2011
   
 
Experimental and Toxicologic Pathology  editor
 
2014
   
 
Annuals of Clinical Pathology  editor
 
2014
 - 
2016
International Federation of Toxicologic Pathology  Executive Committee member
 
2014
   
 
Austin Journal of Clinical Pathology  Editorial board members
 
2014
   
 
International Journal of Laboratory Medicine & Research  Editorial board members
 
2014
   
 
International Journal of Ophthalmic Research  
 

Awards & Honors

 
2013
2012 Best Paper Award, Journal of Toxicologic Pathology
 
2016
2015 JTP Best-Case-Report-of-the-Year Award
 

Published Papers

 
Ramos MF, Baker J, Atzpodien EA, Bach U, Brassard J, Cartwright J, Farman C, Fishman C, Jacobsen M, Junker-Walker U, Kuper F, Moreno MCR, Rittinghausen S, Schafer K, Tanaka K, Teixeira L, Yoshizawa K, Zhang H
Journal of toxicologic pathology   31(3 Suppl) 97S-214S   2018   [Refereed]
Naito Y, Yoshikawa Y, Yoshizawa K, Takenouchi A, Yasui H
In vivo (Athens, Greece)   31(6) 1145-1151   Nov 2017   [Refereed]
Yuki M, Emoto Y, Yoshizawa K, Yuri T, Tsubura A
Case reports in gastroenterology   10(3) 629-632   Sep 2016   [Refereed]
Yoshizawa K, Yuki M, Kinoshita Y, Emoto Y, Yuri T, Elmore SA, Tsubura A
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie   68(7) 371-379   Aug 2016   [Refereed]
Yuri T, Yoshizawa K, Emoto Y, Kinoshita Y, Yuki M, Tsubura A
In vivo (Athens, Greece)   30(6) 795-800   2016   [Refereed]
Keenan CM, Baker JF, Bradley AE, Goodman DG, Harada T, Herbert R, Kaufmann W, Kellner R, Mahler B, Meseck E, Nolte T, Rittinghausen S, Vahle J, Yoshizawa K
Journal of toxicologic pathology   28(1) 51-53   Jan 2015   [Refereed]
Moroki T, Yoshikawa Y, Yoshizawa K, Tsubura A, Yasui H
Metallomics : integrated biometal science   6(9) 1632-1638   Sep 2014   [Refereed]
Morphological characterization of systemic changes in KK-Ay mice as an animal model of type 2 diabetes.
Moroki T, Yoshikawa Y, Yoshizawa K, Tsubura A, Yasui H
In vivo (Athens, Greece)   27(4) 465-472   Jul 2013   [Refereed]
Review: Animal models of N-Methyl-N-nitrosourea-induced mammary cancer and retinal degeneration with special emphasis on therapeutic trials.
Tsubura A, Lai YC, Miki H, Sasaki T, Uehara N, Yuri T, Yoshizawa K
In vivo (Athens, Greece)   25(1) 11-22   Jan 2011   [Refereed]
Yoshizawa K
Nihon yakurigaku zasshi. Folia pharmacologica Japonica   131(4) 285-290   Apr 2008   [Refereed]
Ischemic brain damage after ketamine and xylazine treatment in a young laboratory monkey (Macaca fascicularis).
Yoshizawa K, Oishi Y, Matsumoto M, Nyska A
Contemporary topics in laboratory animal science   44(5) 19-24   Sep 2005   [Refereed]
[Characteristics of N-methyl-N-nitrosourea-induced retinal degeneration in animals and application for the therapy of human retinitis pigmentosa].
Yoshizawa K, Tsubura A
Nippon Ganka Gakkai zasshi   109(6) 327-337   Jun 2005   [Refereed]

Misc

 
竹之内明子, 榎本祐子, 木下勇一, 浜崎景, 螺良愛郎, 義澤克彦
日本毒性病理学会講演要旨集   34th 86(JA),200(EN)-86   Jan 2018
Mammalian target of rapamycin(mTOR)シグナル遺伝子改変マウスを用いた嚢胞腎および腎癌の発症分子機構
塚口 裕康, 義澤 克彦, Nguyen Thanh Huan, 辻 章志, 木下 秀文, 松田 達志
関西医科大学雑誌   68 34-34   Dec 2017
カンタキサンチン・アスタキサンチン摂取によるMNU誘発ラット乳腺発癌予防効果の検証
圦 貴司, 義澤 克彦
乳癌基礎研究   25 27-31   Apr 2017
3週齢雌のSprague-Dawleyラット90匹を基礎食群、低用量群、高用量群、カンタキサンチン(Cx)群、アスタキサンチン(Ax)群の5群各18匹に分け、N-メチル-N-ニトロスウレア(MNU)誘発ラット乳癌モデルを用い、発癌のイニシエーション期/早期プロモーション期におけるCx、Ax摂取が乳癌発生に影響を及ぼすか、実験病理学的に検討し、その作用機序について検証した。1日当たりの食餌摂取量は基礎食群とCx群、Ax群で差はなかった。1日当たりのキサントフィル摂取量は低用量Cx群・Ax群に...
木下勇一, 木下勇一, 義澤克彦, 浜崎景, 河島洋, 榎本裕子, 結城美智子, 圦貴司, 螺良愛郎
日本病理学会会誌   105(1) 471-471   Apr 2016
SEND(非臨床試験電子データ標準化) その規制動向と実装に向けた企業、CRO、ITベンダーの取り組み INHANDの活動とSENDの関係について
義澤 克彦, 原田 孝則
The Journal of Toxicological Sciences   41(Suppl.) S34-S34   Jun 2016

Books etc

 
Animal Models for the Study of Human Disease, 1st edition.
Katsuhiko Yoshizawa, Maki Kuwata, and Airi Tsubura. (Part:Joint Work)
Academic Press / Elsevier   Apr 2013   
Toxic Heart Muscle Disease. Encyclopedic Reference of Molecular Mechanisms of Disease
Springer   Apr 2009   ISBN:103540671366
CD(SD)IGS-1999
Noto T, Oishi Y, Fujihira S, Matsumoto M, Yoshizawa K, Tsubota K, Hashimoto M, and Ohara K. (Part:Joint Work, Spontaneous lesions in Crj:CD(SD)IGS rats versus in Jcl:SD rats used in toxicity studies - histopathological findings -. CD(SD)IGS-1999)
Apr 1999   
Methylnitrosourea. In: Encyclopedia of Toxicology, 3rd Ed.. Elsevier, Acadenuc Press
Elsevier, Acadenuc Press   2014   
N-Methyl-N-nitrosourea-induced retinal degeneration in rats: A reliable animal model of retinitis pigmentosa for the development of new therapeutic strategies. Recent Advances in Eye Research
Nova Science   2015   ISBN:978-1-63463-375-8

Conference Activities & Talks

 
A spontaneously occurring malignant ovarian Sertoli cell tumor in a young Sprague-dawley rat.
第3回日本獣医病理専門家協会学術集会   2016   
INHAND and collaboration with the FDA on SEND – Background and Current Status
36th Annual Meeting, American College of Toxicology   2015   
Diagnostic intraocular lesions using vitreous humor and intraocular perfusion fluid cytology.
The 7th Japan・Taiwan・Korea Cytotechn Joint Meeting,   2015   
INHAND and collaboration with the FDA on SEND – Background and Current Status
35th Annual Meeting, American College of Toxicology   2014   
Morphological analysis of the pancreas and liver in diabetic KK-Ay mice treated with zinc or oxovanadium complexes.
第24回金属の関与する生体関連反応シンポジウム   2014   
Inhibition of in vivo cell motility and invasive potential by microRNA-148a in human breast cancer cells.
第72回日本癌学会学術総会   2013   
N-Methyl-N-nitrosourea-induced renal tumors in rats: Immunohistochemical comparison to human Wilms tumors.
Soc Toxicol Pathol   2013   
MNU-induced renal tumors in rats: Immunohistochemical comparison to human Wilms tumors.
第155回日本獣医学会学術集会   2013   
A perplexing pancreatic lesion.
第29回日本毒性病理学会   2013   
Arachidonic acid supplementation during gestational, lactational and post-weaning periods prevents retinal degeration induced by N-methyl-N-nitrosourea in young Lewis rats.
第39回日本毒性学会/The 6th Int Cong Asian Soc Toxicol   2012   
Degeneration induced in adult mice by a single intraperitoneal injection of N-ethyl-N-nitrosourea.
Soc Toxicol Pathol / 30th Annual Symposium Toxicol Pathol and the immune system   2011   
Calpain inhibition restores basal autophagy and suppresses apoptosis on MNU-induced photoreceptor cell injury in mice
Association for Reseach in Vision and Ophthalmology   2011   
Short-term pregnancy hormone treatment on N-methyl-N-nitrosourea-induced mammary carcinogenesis in relation to serum fatty acid composition.
HUGO-IABCR Cong 2010   2010   
Cerebromalacia with Epilepsy and Cortical Blindness in an Experimental Japanese Macaque
STP/IFSTP 2010 Joint Symposium   2010   
Introducing the Japanese Society of Toxicologic Pathology
STP/IFSTP 2010 Joint Symposium   2010   
Toxicologic pathology aspects of chemically induced cardiovascular toxicity, as seen in national toxicology program studies.
The 7th Europ Cong Toxicol Pathol   2009   
Ocular toxicity caused by paclitaxel in neonatal Sprague-Dowley rats.
The 28 th Soc Toxicol Pathol Annual Symp   2009   
Toxicologic Pathology Aspects of Chemically Induced Cardiovascular Toxicity, as Seen in National Toxicity Parogram (NTP) Studies
日本毒性病理学会   2009   
A Critical Comparison of Murine Pathology and Epidemiological Data of Dioxins and PCBs.
Society of Toxicologic Pathology   2007   
Thirteen week toxicity study of indole-3-carbinol in B6C3F1 mice and Fischer 344 rats.
Society of Toxicologic Pathology   2007   
Reproductive Lesions in Female Harlan Sprague-Dawley Rats Following Two-year Oral Treatment with Dioxin and Dioxin-like Compounds
Society of Toxicologic Pathology   2007   
Pulmonary Lesions in Female Harlan SD Rats Following Two-Year Oral Treatment with Dioxins
Society of Toxicologic Pathology   2007   
Pulmonary Lesions in Female Harlan SD Rats Following Two-Year Oral Treatment with Dioxins.
日本毒性病理学会   2007   
Thyroid Follicular Lesions Induced by Oral Treatment for Two Years with 2,3,7,8-Tetrachlorodibenzo-p-dioxin and Dioxin-like Compounds in Female Harlan Sprague-Dawley Rats.
Society of Toxicologic Pathology   2006   
Chemical-Induced Atrial Thrombosis in Rodent NTP Studies: Morphological Aspects and Potential Mechanisms.
Society of Toxicologic Pathology   2005   
Mechanisms of Exocrine Pancreatic Toxicity Induced by Oral Treatment with 2,3,7,8-Tetrachlorodibenzo-p-dioxin in Female Harlan Sprague-Dawley Rats.
Society of Toxicologic Pathology   2005   
Ischemic Brain Damage after Ketamine and Xylazine Treatment in a Young Laboratory Monkey (Macaca fascicularis).
Society of Toxicologic Pathology   2005   
Gingival Carcinogenicity in Female Harlan Sprague-Dawley Rats Following Two-year Oral Treatment with 2,3,7,8-Tetrachlorodibenzo-p-dioxin and Dioxin-like Compounds.
Society of Toxicologic Pathology   2005   
Mechanisms and disease control of N-methyl-N-nitrosourea-induced retinal degeneration in animals.
Society of Toxicologic Pathology   2004   
Mechanisms and disease control of N-methyl-N-nitrosourea-induced retinal degeneration in animals.
Jpn Soc Toxicol Pathol/ Int Fed Soc Toxicol Pathol   2004   
Nicotinamide Functionally Rescues N-Methyl-N-Nitrosourea-Induced Retinopathy in Rats.
Association for Research in Vision and Ophthalmology 2003 Annual Meeting   2003   
Nicotinamide prevents N-methyl-N-nitrosourea induced photoreceptor cell apoptosis in rats and mice.
The Association for Research in Vision and Ophthalmology   2002   
Light inhibition reduces MNU-induced photoreceptor apoptosis.
ARVO   2001   
Protective effects of pregnancy and lactation against N-methyl-N-nitrosourea-induced mammary carcinoma in female Lewis rats.
Int Symp. Biol of Cancer Prev and Treat   1999   
N-methyl-N-nitrosourea誘発ラット雄乳癌の免疫組織学的特徴:雌との相違.
第56回日本組織細胞化学会   2015   
妊娠に関連するホルモンによる乳癌治療の可能性:hCGによるヒト乳癌細胞株の増殖抑制効果.
第102回日本病理学会   2013   

Others

 
Jun 2010   IATP, Fellow
Oct 2002   DJST