論文

2023年2月22日

Left atrial strain assessment using cardiac computed tomography in patients with hypertrophic cardiomyopathy.

Japanese journal of radiology
  • Takaaki Hosokawa
  • Hiroshi Kawakami
  • Yuki Tanabe
  • Naoki Fukuyama
  • Kazuki Yoshida
  • Kentaro Ohara
  • Takuya Kitamura
  • Naoto Kawaguchi
  • Tomoyuki Kido
  • Takayuki Nagai
  • Katsuji Inoue
  • Osamu Yamaguchi
  • Teruhito Kido
  • 全て表示

記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1007/s11604-023-01401-6

PURPOSE: To evaluate left atrial (LA) function in patients with hypertrophic cardiomyopathy (HCM) by LA strain assessment using cardiac computed tomography (CT-derived LA strain). MATERIALS AND METHODS: This was a retrospective study of 34 patients with HCM and 31 non-HCM patients who underwent cardiac computed tomography (CT) using retrospective electrocardiogram-gated mode. CT images were reconstructed every 5% (0-95%) of the RR intervals. CT-derived LA strain (reservoir [LASr], conduit [LASc], and booster pump strain [LASp]) were semi-automatically analyzed using a dedicated workstation. We also measured the left atrial volume index (LAVI) and left ventricular longitudinal strain (LVLS) for the left atrial and ventricular functional parameters to assess the relationship with CT-derived LA strain. RESULTS: CT-derived LA strain significantly correlated with LAVI: r = - 0.69, p < 0.001 for LASr; r = - 0.70, p < 0.001 for LASp; and r = - 0.35, p = 0.004 for LASc. CT-derived LA strain also significantly correlated with LVLS: r = - 0.62, p < 0.001 for LASr; r = - 0.67, p < 0.001 for LASc; and r = - 0.42, p = 0.013 for LASp. CT-derived LA strain in patients with HCM was significantly lower than that in non-HCM patients: LASr (20.8 ± 7.6 vs. 31.7 ± 6.1%, p < 0.001); LASc (7.9 ± 3.4 vs. 14.2 ± 5.3%, p < 0.001); and LASp (12.8 ± 5.7 vs. 17.6 ± 4.3%, p < 0.001). Additionally, CT-derived LA strain showed high reproducibility; inter-observer correlation coefficients were 0.94, 0.90, and 0.89 for LASr, LASc, and LASp, respectively. CONCLUSION: CT-derived LA strain is feasible for quantitative assessment of left atrial function in patients with HCM.

リンク情報
DOI
https://doi.org/10.1007/s11604-023-01401-6
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/36811719
ID情報
  • DOI : 10.1007/s11604-023-01401-6
  • PubMed ID : 36811719

エクスポート
BibTeX RIS