鈴木博紀 (HIRONORI SUZUKI) - マイポータル

基本情報

所属: 物質構造科学研究所構造生物学研究センター研究員

J-GLOBAL ID: 201001045809309749
researchmap会員ID: 6000025549

外部リンク: http://pfweis.kek.jp/index_ja.html

研究キーワード

研究分野

学歴

- 2010年

名古屋大学
- 2007年

名古屋大学
- 2005年

名城大学

受賞

2008年

European Calcium Society Fellowship

MISC

Molecular basis for defect in Alix-binding by alternatively spliced isoform of ALG-2 (ALG-2(Delta GF122)) and structural roles of F122 in target recognition

Tatsutoshi Inuzuka, Hironori Suzuki, Masato Kawasaki, Hideki Shibata, Soichi Wakatsuki, Masatoshi Maki

BMC STRUCTURAL BIOLOGY 10 25 2010年8月
Penta-EF-hand protein ALG-2 functions as a Ca2+-dependent adaptor that bridges Alix and TSG101

Mayumi Okumura, Fumitaka Ichioka, Ryota Kobayashi, Hironori Suzuki, Haruna Yoshida, Hideki Shibata, Masatoshi Maki

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 386(1) 237-241 2009年8月
The mechanism of Ca2+-dependent recognition of Alix by ALG-2: insights from X-ray crystal structures

Hironori Suzuki, Masato Kawasaki, Tatsutoshi Inuzuka, Mayumi Okumura, Takeshi Kakiuchi, Hideki Shibata, Soichi Wakatsuki, Masatoshi Maki

BIOCHEMICAL SOCIETY TRANSACTIONS 37(1) 190-194 2009年2月
Crystallization and X-ray diffraction analysis of N-terminally truncated human ALG-2

Hironori Suzuki, Masato Kawasaki, Takeshi Kakiuchi, Hideki Shibata, Soichi Wakatsuki, Masatoshi Maki

ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS 64(11) 974-977 2008年11月
Structural Basis for Ca2+-Dependent Formation of ALG-2/Alix Peptide Complex: Ca2+/EF3-Driven Arginine Switch Mechanism

Hironori Suzuki, Masato Kawasaki, Tatsutoshi Inuzuka, Mayumi Okumura, Takeshi Kakiuchi, Hideki Shibata, Soichi Wakatsuki, Masatoshi Maki

STRUCTURE 16(10) 1562-1573 2008年10月
Identification of Alix-type and non-Alix-type ALG-2-binding sites in human phospholipid scramblase 3 - Differential binding to an alternatively spliced isoform and amino acid-substituted mutants

Hideki Shibata, Hironori Suzuki, Takeshi Kakiuchi, Tatsutoshi Inuzuka, Haruna Yoshida, Takako Mizuno, Masatoshi Maki

JOURNAL OF BIOLOGICAL CHEMISTRY 283(15) 9623-9632 2008年4月
ALG-2 directly binds Sec31A and localizes at endoplasmic reticulum exit sites in a Ca2+-dependent manner

Hideki Shibata, Hironori Suzuki, Haruna Yoshida, Masatoshi Maki

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 353(3) 756-763 2007年2月
HD-PTP and Alix share some membrane-traffic related proteins that interact with their Bro1 domains or proline-rich regions

Fumitaka Ichioka, Emi Takaya, Hironori Suzuki, Sachiko Kajigaya, Vladimir L. Buchman, Hideki Shibata, Masatoshi Maki

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 457(2) 142-149 2007年1月

講演・口頭発表等

X-ray structure analysis of ESCRT-associated proteins.

The 2009 Nagoya Workshop on International Animal Biotechnology Partnership and Internship 2009年
Elucidation of the calcium dependent interaction mechanism between ALG-2 and Alix by X-ray crystallographic analysis.

European Calcium Society meeting 2008年
X線結晶解析により明らかになったアポトーシス関連因子ALG-2のCa2+依存的な構造変化

日本農芸化学会 2008年
The crystal structure of apoptosis-linked gene 2, a member of Penta-EF-hand protein family.

日本分子生物学会年会・日本生化学会大会合同大会 2007年
The crystal structure of apoptosis-linked gene 2, a member of Penta-EF-hand protein family.

日本分子生物学会年会・日本生化学会大会合同大会 2007年
Identification and characterization of two calcium dependent ALG-2 binding sites in phospholipid scramblase 3.

IUBMB (国際生化学・分子生物学会議) 2006年
Mutational analyses of interactions between ALG-2 and its binding partners.

European Calcium Society meeting 2006年
Mutational analyses of interactions between ALG-2 and it binding partners.

European Calcium Society meeting 2006年

共同研究・競争的資金等の研究課題

細胞内小胞輸送に関わる因子のX線結晶構造解析

共同研究