論文

2017年5月

Measurements of radon activity concentration in mouse tissues and organs

RADIATION AND ENVIRONMENTAL BIOPHYSICS
  • Yuu Ishimori
  • ,
  • Hiroshi Tanaka
  • ,
  • Akihiro Sakoda
  • ,
  • Takahiro Kataoka
  • ,
  • Kiyonori Yamaoka
  • ,
  • Fumihiro Mitsunobu

56
2
開始ページ
161
終了ページ
165
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1007/s00411-017-0682-9
出版者・発行元
SPRINGER

The purpose of this study is to investigate the biokinetics of inhaled radon, radon activity concentrations in mouse tissues and organs were determined after mice had been exposed to about 1 MBq/m(3) of radon in air. Radon activity concentrations in mouse blood and in other tissues and organs were measured with a liquid scintillation counter and with a well-type HP Ge detector, respectively. Radon activity concentration in mouse blood was 0.410 +/- 0.016 Bq/g when saturated with 1 MBq/m(3) of radon activity concentration in air. In addition, average partition coefficients obtained were 0.74 +/- 0.19 for liver, 0.46 +/- 0.13 for muscle, 9.09 +/- 0.49 for adipose tissue, and 0.22 +/- 0.04 for other organs. With these results, a value of 0.414 for the blood-to-air partition coefficient was calculated by means of our physiologically based pharmacokinetic model. The time variation of radon activity concentration in mouse blood during exposure to radon was also calculated. All results are compared in detail with those found in the literature.

リンク情報
DOI
https://doi.org/10.1007/s00411-017-0682-9
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000399996800003&DestApp=WOS_CPL
ID情報
  • DOI : 10.1007/s00411-017-0682-9
  • ISSN : 0301-634X
  • eISSN : 1432-2099
  • Web of Science ID : WOS:000399996800003

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