河合慶親 (Yoshichika Kawai) - マイポータル

基本情報

学位: 博士（農学）(名古屋大学)

J-GLOBAL ID: 201101026381709332
researchmap会員ID: 6000030054

研究キーワード

研究分野

ライフサイエンス / 食品科学 /

経歴

2003年11月 - 2011年3月

徳島大学大学院ヘルスバイオサイエンス研究部・助教
名古屋大学

学歴

委員歴

日本酸化ストレス学会, 評議員

受賞

2009年

2009年度農芸化学奨励賞

MISC

Mitochondrial Dysfunction Leads to Deconjugation of Quercetin Glucuronides in Inflammatory Macrophages

Akari Ishisaka, Kyuichi Kawabata, Satomi Miki, Yuko Shiba, Shoko Minekawa, Tomomi Nishikawa, Rie Mukai, Junji Terao, Yoshichika Kawai

PLOS ONE 8(11) e80843 2013年11月
Atg7 Modulates p53 Activity to Regulate Cell Cycle and Survival During Metabolic Stress

In Hye Lee, Yoshichika Kawai, Maria M. Fergusson, Ilsa I. Rovira, Alexander J. R. Bishop, Noboru Motoyama, Liu Cao, Toren Finkel

SCIENCE 336(6078) 225-228 2012年4月
Accumulation of orally administered quercetin in brain tissue and its antioxidative effects in rats

Akari Ishisaka, Satomi Ichikawa, Hiroyuki Sakakibara, Mariusz K. Piskula, Toshiyuki Nakamura, Yoji Kato, Mikiko Ito, Ken-ichi Miyamoto, Akira Tsuji, Yoshichika Kawai …

FREE RADICAL BIOLOGY AND MEDICINE 51(7) 1329-1336 2011年10月
Immunochemical Detection of Food-Derived Polyphenols in the Aorta: Macrophages as a Major Target Underlying the Anti-Atherosclerotic Activity of Polyphenols

Yoshichika Kawai

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 75(4) 609-617 2011年4月
Immunochemical detection of food-derived polyphenols in the aorta: Macrophages as a major target underlying the anti-atherosclerotic activity of polyphenols

Yoshichika Kawai

Bioscience, Biotechnology and Biochemistry 75(4) 609-617 2011年
Different Profiles of Quercetin Metabolites in Rat Plasma: Comparison of Two Administration Methods

Yoshichika Kawai, Satomi Saito, Tomomi Nishikawa, Akari Ishisaka, Kaeko Murota, Junji Terao

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 73(3) 517-523 2009年3月
(-)-epicatechin gallate accumulates in foamy macrophages in human atherosclerotic aorta: Implication in the anti-atherosclerotic actions of tea catechins

Yoshichika Kawai, Hiroko Tanaka, Kaeko Murota, Michitaka Naito, Junji Terao

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 374(3) 527-532 2008年9月
Immunochemical detection of flavonoid glycosides: Development, specificity, and application of novel monoclonal antibodies

Yoshichika Kawai, Akari Ishisaka, Satomi Saito, Koji Uchida, Noriyuki Shibata, Makio Kobayashi, Yoshiko Fukuchi, Michitaka Naito, Junjji Terao

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 476(2) 124-132 2008年8月
Flavonoids as substrates and inhibitors of myeloperoxidase: Molecular actions of aglycone and metabolites

Yuko Shiba, Takashi Kinoshita, Hiroshi Chuman, Yutaka Taketani, Eiji Takeda, Yoji Kato, Michitaka Naito, Kyuichi Kawabata, Akari Ishisaka, Junji Terao …

CHEMICAL RESEARCH IN TOXICOLOGY 21(8) 1600-1609 2008年8月
Galloylated catechins as potent inhibitors of hypochlorous acid-induced DNA damage

Yoshichika Kawai, Yuri Matsui, Hajime Kondo, Hiroshi Morinaga, Koji Uchida, Noriyuki Miyoshi, Yoshimasa Nakamura, Toshihiko Osawa

CHEMICAL RESEARCH IN TOXICOLOGY 21(7) 1407-1414 2008年7月
Macrophage as a target of quercetin glucuronides in human atherosclerotic arteries - Implication in the anti-atherosclerotic mechanism of dietary flavonoids

Yoshichika Kawai, Tomomi Nishikawa, Yuko Shiba, Satomi Saito, Kaeko Murota, Noriyuki Shibata, Makio Kobayashi, Masaya Kanayama, Koji Uchida, Junji Terao

JOURNAL OF BIOLOGICAL CHEMISTRY 283(14) 9424-9434 2008年4月
Detection of cholesteryl ester hydroperoxide isomers using gas chromatography-mass spectrometry combined with thin-layer chromatography blotting

Yoshichika Kawai, Mariko Miyoshi, Jae-Hak Moon, Junji Terao

ANALYTICAL BIOCHEMISTRY 360(1) 130-137 2007年1月
Lipidomic analysis for lipid peroxidation-derived aldehydes using gas chromatography-mass spectrometry

Yoshichika Kawai, Sayaka Takeda, Junji Terao

CHEMICAL RESEARCH IN TOXICOLOGY 20(1) 99-107 2007年1月
Hypochlorous acid-derived modification of phospholipids: Characterization of aminophospholipids as regulatory molecules for lipid peroxidation

Yoshichika Kawai, Hitomi Kiyokawa, Yuki Kimura, Yoji Kato, Koichiro Tsuchiya, Junji Terao

BIOCHEMISTRY 45(47) 14201-14211 2006年11月
Formation of N-epsilon-(succinyl)lysine in vivo: a novel marker for docosahexaenoic acid-derived protein modification

Yoshichika Kawai, Hiroyuki Fujii, Miki Okada, Yoshikazu Tsuchie, Koji Uchida, Toshihiko Osawa

JOURNAL OF LIPID RESEARCH 47(7) 1386-1398 2006年7月
Endogenous formation of novel halogenated 2 '-deoxycytidine - Hypohalous acid-mediated DNA modification at the site of inflammation

Y Kawai, H Morinaga, H Kondo, N Miyoshi, Y Nakamura, K Uchida, T Osawa

JOURNAL OF BIOLOGICAL CHEMISTRY 279(49) 51241-51249 2004年12月
2 '-deoxycytidine in free nucleosides and double-stranded DNA, as the major target of lipid peroxidation products

Y Kawai, K Uchida, T Osawa

FREE RADICAL BIOLOGY AND MEDICINE 36(5) 529-541 2004年3月
Esterified lipid hydroperoxide-derived modification of protein: formation of a carboxyalkylamide-type lysine adduct in human atherosclerotic lesions

Y Kawai, H Fujii, Y Kato, M Kodama, M Naito, K Uchida, T Osawa

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 313(2) 271-276 2004年1月
Formation of acrolein-derived 2 '-deoxyadenosine adduct in an iron-induced carcinogenesis model

Y Kawai, A Furuhata, S Toyokuni, Y Aratani, K Uchida

JOURNAL OF BIOLOGICAL CHEMISTRY 278(50) 50346-50354 2003年12月
Covalent binding of oxidized cholesteryl esters to protein - Implications for oxidative modification of low density lipoprotein and atherosclerosis

Y Kawai, A Saito, N Shibata, M Kobayashi, S Yamada, T Osawa, K Uchida

JOURNAL OF BIOLOGICAL CHEMISTRY 278(23) 21040-21049 2003年6月

もっとみる

所属学協会

Works(作品等)

ミトコンドリアDNA付加体による炎症誘導活性評価

2013年4月 - 2015年3月
ミトコンドリア品質管理機構を標的とする食品成分の新機能探索

2011年4月 - 2013年3月
ポリフェノール類の機能性と安全性評価のための標的分子の解析

2007年4月 - 2011年3月
食品の抗酸化機能評価を目指した酸化ストレス産物の一斉解析法の開発

2005年4月 - 2007年3月