2003年
Expression of Bcl-2 on leukocytes in prostatic fluid from patients with acute and chronic prostatitis
Journal of Infection and Chemotherapy
- ,
- ,
- ,
- 巻
- 9
- 号
- 2
- 開始ページ
- 156
- 終了ページ
- 159
- 記述言語
- 英語
- 掲載種別
- DOI
- 10.1007/s10156-003-0238-6
- 出版者・発行元
- Springer Japan
In our continuing investigation to clarify the significance of leukocytosis and its prolongation in prostatic fluid (PF) from prostatitis patients, we investigated whether expression of the antiapoptotic gene Bcl-2 on leukocytes in prostatic fluid has any relation with prolonged leukocytosis in prostatitis. The subjects were eight patients with acute bacterial prostatitis (ABP) and eight with nonbacterial prostatitis (NBP) with a history of more than 2 years. Twelve micrograms of protein obtained from leukocytes in PF were subjected to Western blot analysis, Bcl-2 was expressed in seven of eight (87.5%) and six of eight (75.0%) patients with NBP and ABP, respectively. Quantitative density analysis of the Bcl-2 band did not show any statistically significant differences between patients with NBP and those with ABP. These results suggest that the expression of antiapoptotic Bcl-2 on leukocytes in PF is not a cause of leukocyte longevity in long-term prostatitis.
- リンク情報
- ID情報
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- DOI : 10.1007/s10156-003-0238-6
- ISSN : 1341-321X
- PubMed ID : 12825115
- SCOPUS ID : 0038607781