Reiji Kannagi - My portal - researchmap

Profile Information

Affiliation: Head, Division of Molecular Pathology, Aichi Cancer Center, Research Institute

Degree: M.D., Ph.D.

J-GLOBAL ID: 200901045019206493
researchmap Member ID: 0000020517

Research Interests

6

Research Areas

3

Research History

2

1985

Faculty of Medicine, Kyoto University
1982

Faculty of Medicine, Kyoto University

Education

2

Committee Memberships

5

Awards

2

Misc.

89

Human B-lymphocytes express alpha 2-6-sialylated 6-sulfo-N-acetyllactosamine serving as a preferred ligand for CD22/Siglec-2

Naoko Kimura, Katsuyuki Ohmori, Keiko Miyazaki, Mineko Izawa, Yuji Matsuzaki, Yosuke Yasuda, Hiromu Takematsu, Yasunori Kozutsumi, Akihiko Moriyama, Reiji Kannagi

JOURNAL OF BIOLOGICAL CHEMISTRY, 282(44) 32200-32207, Nov, 2007
Interaction of GATA-3/T-bet transcription factors regulates expression of sialyl Lewis X homing receptors on Th1/Th2 lymphocytes

Guo-Yun Chen, Hirotaka Osada, Luis F. Santamaria-Babi, Reiji Kannagi

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 103(45) 16894-16899, Nov, 2006
Rapid demonstration of diversity of sulfatide molecular species from biological materials by MALDI-TOF MS

Mamoru Kyogashima, Keiko Tamiya-Koizumi, Takashi Ehara, Gang Li, Rui Hu, Atsushi Hara, Toshifumi Aoyama, Reiji Kannagi

GLYCOBIOLOGY, 16(8) 719-728, Aug, 2006
Identification of cutaneous lymphocyte-associated antigen as sialyl 6-sulfo Lewis X, a selectin ligand expressed on a subset of skin-homing helper memory T cells

K Ohmori, F Fukui, M Kiso, T Imai, O Yoshie, H Hasegawa, K Matsushima, R Kannagi

BLOOD, 107(8) 3197-3204, Apr, 2006
Hypoxic culture induces expression of sialin, a sialic acid transporter, and cancer-associated gangliosides containing non-human sialic acid on human cancer cells

J Yin, A Hashimoto, M Izawa, K Miyazaki, GY Chen, H Takematsu, Y Kozutsumi, A Suzuki, K Furuhata, FL Cheng …

CANCER RESEARCH, 66(6) 2937-2945, Mar, 2006
A major class of L-selectin ligands is eliminated in mice deficient in two sulfotransferases expressed in high endothelial venules

K Uchimura, JM Gauguet, MS Singer, D Tsay, R Kannagi, T Muramatsu, UH von Andrian, SD Rosen

NATURE IMMUNOLOGY, 6(11) 1105-1113, Nov, 2005
N-acetylglucosamine 6-O-sulfotransferase-1 regulates expression of L-selectin ligands and lymphocyte homing

K Uchimura, K Kadomatsu, FM El-Fasakhany, MS Singer, M Izawa, R Kannagi, N Takeda, SD Rosen, T Muramatsu

JOURNAL OF BIOLOGICAL CHEMISTRY, 279(33) 35001-35008, Aug, 2004
Carbohydrate-mediated cell adhesion in cancer metastasis and angiogenesis.

Cancer Sci., 95: 377-384, 2004
In search of the carbohydrate structures on CD44 critical for hyaluronic acid binding - roles of sialylation and sulfation.

Trends Glycosci. Glycotechnol., 16: 211-223,, 2004
Hypoxia induces adhesion molecules on cancer cells-a missing link between Warburg effect and induction of selectin ligand carbohydrates.

Proc. Natl. Acad. Sci. USA, 101: 8132-8137, 2004
Loss of disialyl Lewis a, the ligand for lymphocyte inhibitory receptor Siglec-7, associated with increased sialyl Lewis a expression on human colon cancers.

Cancer Res, 64: 4498-4505, 2004
Synthesis of disialyl Lewis a (Le(a)) structure in colon cancer cell lines by a sialyltransferase, ST6GalNAc VI, responsible for the synthesis of alpha-series gangliosides

A Tsuchida, T Okajima, K Furukawa, T Ando, H Ishida, A Yoshida, Y Nakamura, R Kannagi, M Kiso, K Furukawa

JOURNAL OF BIOLOGICAL CHEMISTRY, 278(25) 22787-22794, Jun, 2003
Transactivation of the fucosyltransferase VII gene by human T-cell leukemia virus type 1 Tax through a variant cAMP-responsive element

N Hiraiwa, T Yabuta, K Yoritomi, M Hiraiwa, Y Tanaka, T Suzuki, M Yoshida, R Kannagi

BLOOD, 101(9) 3615-3621, May, 2003
Molecular mechanism for cancer-associated induction of sialyl Lewis X and sialyl Lewis A expression - The Warburg effect revisited

Reiji Kannagi

Glycoconjugate Journal, 20(5) 353-364, 2003
Specificities of N-acetylglucosamine-6-O-sulfotransferases in relation to L-selectin ligand synthesis and tumor-associated enzyme expression

K Uchimura, FM El-Fasakhany, M Hori, S Hemmerich, SE Blink, GS Kansas, A Kanamori, K Kumamoto, R Kannagi, T Muramatsu

JOURNAL OF BIOLOGICAL CHEMISTRY, 277(6) 3979-3984, Feb, 2002
Specificities of N-acetylglucosamine-6-O-sulfotransferases in relation to L-selectin ligand synthesis and tumor-associated enzyme expression

K Uchimura, FM El-Fasakhany, M Hori, S Hemmerich, SE Blink, GS Kansas, A Kanamori, K Kumamoto, R Kannagi, T Muramatsu

JOURNAL OF BIOLOGICAL CHEMISTRY, 277(6) 3979-3984, Feb, 2002
6-Sulfo LacNAc, a novel carbohydrate modification of PSGL-1, defines an inflammatory type of human dendritic cells.

Immunity, 17: 289-301, 2002
Regulatory roles of carbohydrate ligands for selectins in homing of lymphocytes.

Curr. Opin. Struct. Biol., 12: 599-608, 2002
Distinct sulfation requirements of selectins disclosed using cells which support rolling mediated by all three selectins under shear flow: L-selectin prefers carbohydrate 6-sulfation to tyrosine sulfation whereas P-selectin does not.

J. Biol. Chem., 277: 32578-32586, 2002
Roles of cell adhesion molecules in tumor angiogenesis induced by co-transplantation of cancer and endothelial cells to nude rats.

Cancer Res., 62: 6289-6296, 2002

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