論文

2008年

Estimation models for the morbidity of the horses infected with equine influenza virus

Journal of Equine Science
  • Shigeo Sugita
  • ,
  • Hironori Oki
  • ,
  • Telhisa Hasegawa
  • ,
  • Nobushige Ishida

19
3
開始ページ
63
終了ページ
66
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1294/jes.19.63

Estimation formulas for the morbidity of horses infected with equine influenza virus by linear regression, logistic regression and probit transformation were developed, using data from the outbreak at the Sha Tin Racing Track in Hong Kong in 1992. Using these formulas, we estimated the equine influenza virus morbidity rates at training centers belonging to the Japan Racing Association (JRA) in October 1997 and in October 1998. In 1998 JRA started a new vaccination program, and every horse must now be vaccinated twice per year. At that time, the vaccine included two US lineage virus strains, the A/equine/Kentucky/81 strain and the A/equine/La Plata/93 (LP93) strain, against equine type-2 influenza viruses
it did not include any EU lineage virus strains, such as A/equine/Suffolk/89 (SF89). Comparing the geometric mean (GM) values of hemagglutination inhibition (HI) titers between the LP93 strain and the SF89 strain in 1997 and in 1998, they both rose significantly at every age (p&lt
0.05) by Wilcoxon test. Calculations by the simulation models show the morbidity rates for LP93 diminished from 0.439 (linear), 0.423 (logistic) and 0.431 (probit) to 0.276 (linear), 0.265 (logistic) and 0.271 (probit), respectively. On the other hand, the estimated morbidity rates for SF89 diminished only slightly from 0.954 (linear), 0.932 (logistic) and 0.944 (probit) to 0.946 (linear), 0.914 (logistic) and 0.927 (probit), respectively. Our simulation models could estimate the effect of the vaccine on each of the equine virus strains represented by the morbidity of infected horses. Thus, they are useful for vaccine evaluation.

リンク情報
DOI
https://doi.org/10.1294/jes.19.63
CiNii Articles
http://ci.nii.ac.jp/naid/10024336711
ID情報
  • DOI : 10.1294/jes.19.63
  • ISSN : 1340-3516
  • ISSN : 1347-7501
  • CiNii Articles ID : 10024336711
  • SCOPUS ID : 54949092390

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