大竹徹 (Toru Otake) - マイポータル - researchmap

基本情報

所属: 旧所属大阪府立公衆衛生研究所感染症部ウイルス課ウイルス課長

学位: 医学博士(鳥取大学)

J-GLOBAL ID: 200901036804611749
researchmap会員ID: 0000026062

外部リンク: http://www.iph.pref.osaka.jp/Eindex.html

研究キーワード

15

研究分野

1

ライフサイエンス / ウイルス学 /

経歴

2

1971年

- 大阪府立公衆衛生研究所
1971年

- Osaka Prefectural Institute of Public Health

学歴

2

- 1971年

鳥取大学, 農学部, 獣医学科
- 1971年

University of Tottori, Department of Agriculture, Veterinary Science

MISC

99

HIV-1 integrase inhibitory substances from Coleus parvifolius

S Tewtrakul, H Miyashiro, N Nakamura, M Hattori, T Kawahata, T Otake, T Yoshinaga, T Fujiwara, T Supavita, S Yuenyongsawad …

PHYTOTHERAPY RESEARCH 17(3) 232-239 2003年3月
HIV-1 integrase inhibitory substances from Coleus parvifolius

S Tewtrakul, H Miyashiro, N Nakamura, M Hattori, T Kawahata, T Otake, T Yoshinaga, T Fujiwara, T Supavita, S Yuenyongsawad …

PHYTOTHERAPY RESEARCH 17(3) 232-239 2003年3月
A novel substance purified from Perilla frutescens Britton inhibits an early stage of HIV-1 replication without blocking viral adsorption

T. Kawahata, T. Otake, H. Mori, Y. Kojima, I. Oishi, S. Oka, Y. Fukumori, K. Sano

Antiviral Chemistry and Chemotherapy 13(5) 283-288 2002年
Synthesis and evaluation of anti-HIV-1 and anti-HSV-1 activities of 4H-[1,2,4]-triazolo[1,5-a]pyrimidin-5-one derivatives

AA Abdel-Hafez, HAH Elsherief, M Jo, M Kurokawa, K Shiraki, T Kawahata, T Otake, N Nakamura, M Hattori

ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH 52(11) 833-839 2002年
Inhibition effects of triterpene-azidothymidine conjugates on proliferation of human immunodeficiency virus type 1 and its protease(Ma C, Nakamura N, Hattori M, Kawahata T, Otake T)

Chemical and Pharmaceutical Bulletin, 50, 877-550, 2002年
Screening of Chinese and Mongloian herbal drugs for anti-human immunodeficiency virus type 1(HIV-1) activity (Ma C, Nakamura N, Miyashiro H, Hattori M, Komatsu K, Kawahata T, Otake T)

Phytotherapy Research, 16, 186-189, 2002年
Ability to induce p53 and caspase-mediated apoptosis in primary CD4+ T cells is variable among primary isolates of human immunodeficiency virus type 1(Komoto S, Kinomoto M, Horikoshi H, Shiraga M, Kurosu T, Mukai T, Auwanit W, Otake T, Oishi I, Ikuta K)

AIDS Research and Human Retroviruses, 18, 435-446, 2002年
Inhibition of cytophathec effect of human immunodeficiency virus type-1 by various phorbol derivatives(El-Makkawy S, Meselhy M R, Abdel-Hafez A A M, Nakamura N, Hattori M, Kawahata T, Otake T)

Chemical and Pharmaceutical Bulletin, 50, 523-529, 2002年
Resting CD4+T cell with CD38+CD62L+ produce interleukin-4 which contributes to enhances replication of T-tropic human immunodeficiency virus type 1(Horikoshi H, Kinomoto M, Kurosu T, Komoto S, Shiraga M, Otake T, Mukai T, Ikuta K)

Virology, 293, 94-102, 2002年
A novel substance purified from Perilla frutescens Britton inhibits an early stage of HIV-1 replication without blocking viral adsorption

T. Kawahata, T. Otake, H. Mori, Y. Kojima, I. Oishi, S. Oka, Y. Fukumori, K. Sano

Antiviral Chemistry and Chemotherapy 13(5) 283-288 2002年
Synthesis and evaluation of anti-HIV-1 and anti-HSV-1 activities of 4H-[1,2,4]-triazolo[1,5-a]pyrimidin-5-one derivatives

AA Abdel-Hafez, HAH Elsherief, M Jo, M Kurokawa, K Shiraki, T Kawahata, T Otake, N Nakamura, M Hattori

ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH 52(11) 833-839 2002年
Inhibition effects of triterpene-azidothymidine conjugates on proliferation of human immunodeficiency virus type 1 and its protease(Ma C, Nakamura N, Hattori M, Kawahata T, Otake T)

Chemical and Pharmaceutical Bulletin, 50, 877-550, 2002年
Screening of Chinese and Mongloian herbal drugs for anti-human immunodeficiency virus type 1(HIV-1) activity (Ma C, Nakamura N, Miyashiro H, Hattori M, Komatsu K, Kawahata T, Otake T)

Phytotherapy Research, 16, 186-189, 2002年
Ability to induce p53 and caspase-mediated apoptosis in primary CD4+ T cells is variable among primary isolates of human immunodeficiency virus type 1(Komoto S, Kinomoto M, Horikoshi H, Shiraga M, Kurosu T, Mukai T, Auwanit W, Otake T, Oishi I, Ikuta K)

AIDS Research and Human Retroviruses, 18, 435-446, 2002年
Inhibition of cytophathec effect of human immunodeficiency virus type-1 by various phorbol derivatives(El-Makkawy S, Meselhy M R, Abdel-Hafez A A M, Nakamura N, Hattori M, Kawahata T, Otake T)

Chemical and Pharmaceutical Bulletin, 50, 523-529, 2002年
Resting CD4+T cell with CD38+CD62L+ produce interleukin-4 which contributes to enhances replication of T-tropic human immunodeficiency virus type 1(Horikoshi H, Kinomoto M, Kurosu T, Komoto S, Shiraga M, Otake T, Mukai T, Ikuta K)

Virology, 293, 94-102, 2002年
Inhibitory effects of Korean plants on HIV-1 activity(Min B S, Kim Y H, Tomiyama M, Nakamura N, Miyashiro H, Otake T, Hattori M)

Phytotherapy Research, 15, 481-486, 2001年
Effect of size of man-made and natural mineral fibers on chemiluminescent response in human monocyte-derived macrophages(Ohyama M, Otake T, Morinaga K)

Environmental Health Perspectives, 109, 1033-1038, 2001年
Low or no antibody responses to human immunodeficiency virus type 1 Nef in infected carriers with subtype E, in contrast to sbtype B that showed antibodies preferenitially(Komoto S, Kinomoto M, Ibrahim M S, Zhong Q, Auwanit W, Ayuthaya P I N, Otake T, ・・・

Vaccine, 19, 3019-3032, 2001年
Inhibitory effects of Korean plants on HIV-1 activity(Min B S, Kim Y H, Tomiyama M, Nakamura N, Miyashiro H, Otake T, Hattori M)

Phytotherapy Research, 15, 481-486, 2001年

もっとみる

所属学協会

12

Works(作品等)

2

新規抗HIV剤の開発

1988年
Development of new anti-HIV agents

1988年

共同研究・競争的資金等の研究課題

4

AIDS/HIV感染症におけるウイルス学的診断法，抗HIV剤の開発

厚生労働科学研究費補助金 1985年 - 2008年
Virologecal diagnosis for AIDS/HIV infection, Anti-HIV agents

Health and Labour Sciences Research Grants 1985年 - 2008年
高圧処理による血液製剤の無毒化
Detoxication of blood products by highpressure

産業財産権

10