池田和子 (Kazuko OKAMURA) - マイポータル

基本情報

所属: 徳島大学疾患酵素学研究センター酵素分子生理学部門助手

学位: 医学博士(徳島大学)

通称等の別名: IKEDA Kazuko
J-GLOBAL ID: 200901052935064536
researchmap会員ID: 0000027210

外部リンク: http://mms1.ier.tokushima-u.ac.jp/bunshi-seiri/bunshi-seiri.html

研究キーワード

研究分野

MISC

Crystal structure of human T-protein of glycine cleavage system at 2.0 angstrom resolution and its implication for understanding non-ketotic hyperglycinemia

K Okamura-Ikeda, H Hosaka, M Yoshimura, E Yamashita, S Toma, A Nakagawa, K Fujiwara, Y Motokawa, H Taniguchi

JOURNAL OF MOLECULAR BIOLOGY 351(5) 1146-1159 2005年9月
Crystal structure of lipoate-protein ligase a from Escherichia coli - Determination of the lipoic acid-binding site

K Fujiwara, S Toma, K Okamura-Ikeda, Y Motokawa, A Nakagawa, H Taniguchi

JOURNAL OF BIOLOGICAL CHEMISTRY 280(39) 33645-33651 2005年9月
Probing the H-protein-induced conformational change and the function of the N-terminal region of Escherichia coli T-protein of the glycine cleavage system by limited proteolysis

K Okamura-Ikeda, N Kameoka, K Fujiwara, Y Motokawa

JOURNAL OF BIOLOGICAL CHEMISTRY 278(12) 10067-10072 2003年3月
Purification, Characterization, and cDNA Cloning of Lipoate-activating Enzyme from Bovine Liver

Kazuko Fujiwara, Shinji Takeuchi, Kazuko Okamura-Ikeda, Yutaro Motokawa

Journal of Biological Chemistry 276(31) 28819-28823 2001年8月3日
Purification, Characterization, and cDNA Cloning of Lipoate-activating Enzyme from Bovine Liver

Kazuko Fujiwara, Shinji Takeuchi, Kazuko Okamura-Ikeda, Yutaro Motokawa

Journal of Biological Chemistry 276(31) 28819-28823 2001年8月3日
The amino-terminal region of the Escherichia coli T-protein of the glycine cleavage system is essential for proper association with H-protein

Kazuko Okamura-Ikeda, Kazuko Fujiwara, Putaro Motokawa

European Journal of Biochemistry 264(2) 446-452 1999年9月1日
Identification of the folate binding sites on the Escherichia coli T- protein of the glycine cleavage system

Kazuko Okamura-Ikeda, Kazuko Fujiwara, Yutaro Motokawa

Journal of Biological Chemistry 274(25) 17471-17477 1999年6月18日
Molecular cloning, structural characterization and chromosomal localization of human lipoyltransferase gene

Kazuko Fujiwara, Mikio Suzuki, Yasuyo Okumachi, Kazuko Okamura-Ikeda, Tsutomu Fujiwara, Ei-Ichi Takahashi, Yutaro Motokawa

European Journal of Biochemistry 260(3) 761-767 1999年3月15日
Molecular cloning, structural characterization and chromosomal localization of human lipoyltransferase gene

Kazuko Fujiwara, Mikio Suzuki, Yasuyo Okumachi, Kazuko Okamura-Ikeda, Tsutomu Fujiwara, Ei-Ichi Takahashi, Yutaro Motokawa

European Journal of Biochemistry 260(3) 761-767 1999年3月15日
Cloning and expression of a cDNA encoding bovine lipoyltransferase

Kazuko Fujiwara, Kazuko Okamura-Ikeda, Yutaro Motokawa

Journal of Biological Chemistry 272(51) 31974-31978 1997年12月19日
Synthesis and characterization of selenolipoylated H-protein of the glycine cleavage system

Kazuko Fujiwara, Kazuko Okamura-Ikeda, Lester Packer, Yutaro Motokawar

Journal of Biological Chemistry 272(32) 19880-19883 1997年8月8日
Synthesis and characterization of selenolipoylated H-protein of the glycine cleavage system

Kazuko Fujiwara, Kazuko Okamura-Ikeda, Lester Packer, Yutaro Motokawar

Journal of Biological Chemistry 272(32) 19880-19883 1997年8月8日
Lipoylation of acyltransferase components of α-ketoacid dehydrogenase complexes

Kazuko Fujiwara, Kazuko Okamura-Ikeda, Yutaro Motokawa

Journal of Biological Chemistry 271(22) 12932-12936 1996年
Structure and chromosomal localization of the aminomethyltransferase gene (AMT)

Kenji Nanao, Goro Takada, Ei-Ichi Takahashi, Naohiko Seki, Yoriko Komatsu, Kazuko Okamura-Ikeda, Yutaro Motokawa, Kiyoshi Hayasaka

Genomics 19(1) 27-30 1994年
Structure and chromosomal localization of the aminomethyltransferase gene (AMT)

Kenji Nanao, Goro Takada, Ei-Ichi Takahashi, Naohiko Seki, Yoriko Komatsu, Kazuko Okamura-Ikeda, Yutaro Motokawa, Kiyoshi Hayasaka

Genomics 19(1) 27-30 1994年
Isolation and sequence determination of cDNA encoding human T-protein of the glycine cleavage system

Kiyoshi Hayasaka, Kenji Nanao, Goro Takada, Kazuko Okamura-Ikeda, Yutaro Motokawa

Biochemical and Biophysical Research Communications 192(2) 766-771 1993年4月30日
Isolation and sequence determination of cDNA encoding human T-protein of the glycine cleavage system

Kiyoshi Hayasaka, Kenji Nanao, Goro Takada, Kazuko Okamura-Ikeda, Yutaro Motokawa

Biochemical and Biophysical Research Communications 192(2) 766-771 1993年4月30日
Cloning and nucleotide sequence of the gcv operon encoding the Escherichia coli glycine‐cleavage system

Kazuko OKAMURA‐IKEDA, Yosuke OHMURA, Kazuko FUJIWARA, Yutaro MOTOKAWA

European Journal of Biochemistry 216(2) 539-548 1993年
Cloning and nucleotide sequence of the gcv operon encoding the Escherichia coli glycine‐cleavage system

Kazuko OKAMURA‐IKEDA, Yosuke OHMURA, Kazuko FUJIWARA, Yutaro MOTOKAWA

European Journal of Biochemistry 216(2) 539-548 1993年
Isolation and sequence determination of l.c.DNA encoding T-protein of the glycine cleavage system

J. Biol. Chem. 266, 4917-4921 (1991)

もっとみる

書籍等出版物

Activation and transfer of lipoic acid in protein lipoylation in mammals

Thiamin: Catalytic Mechanism and Role in Normal and Disease States (Marcel Dekker, Inc.) 2004年
Role of lipoic acid in the glycine cleavage system and lipoylation of H-protein(Biothiols in Health and Disease

biothiols in Health and Disease pp389-407 Marcel Dekker, Inc. 1995年
Role of lipoic acid in the glycine cleavage system and lipoylation of H-protein

Biothiols in Health and Disease, pp389-407 Marcel Dekker, Inc. 1995年

所属学協会

共同研究・競争的資金等の研究課題

オルガネラプロテオキクスに基ずくペルオキシソーム形成とその障害の分子機構の解明

科学研究費補助金 2002年
Molecular mechanism of peroxisome disease

Grant-in-Aid for Scientific Research 2002年
グリシン開裂酵素系T-蛋白質の構造と機能に関する研究

1978年
The structure and function of T-protein of glycine cleavage system

1978年