田井直 (Tadashi Tai) - マイポータル

基本情報

所属: 旧所属東京都医学研究機構東京都臨床医学総合研究所腫瘍免疫研究部門部長

学位: 医学博士(神戸大学)

J-GLOBAL ID: 200901085272712720
researchmap会員ID: 0000029829

外部リンク: http://www.rinshoken.or.jp/

研究キーワード

研究分野

ライフサイエンス / 構造生物化学 /

MISC

157

Localization of verotoxin receptors in nervous system

Jin Ren, Iku Utsunomiya, Kyoji Taguchi, Toshio Ariga, Tadashi Tai, Yasuo Ihara, Tadashi Miyatake

Brain Research 825(1-2) 183-188 1999年4月17日
Differential distribution of glycosphingolipid antigens in the central nervous system

Tadashi Tai, Masaharu Kotani, Ikuo Kawashima

Acta Histochemica et Cytochemica 32(3) 215-222 1999年
Delineation of the epitope recognized by an antibody specific for N- glycolylneuraminic acid-containing gangliosides

Ernesto Moreno, Boel Lanne, Ana María Vázquez, Ikuo Kawashima, Tadashi Tai, Luis Enrique Fernández, Karl-Anders Karlsson, Jonas Ångström, Rolando Pérez

Glycobiology 8(7) 695-705 1998年7月
An immunocytochemical technique with monoclonal antibodies to glycosphingolipids in rat primary cerebellar cultures: Influence of detergent permeabilization

Ikuo Kawashima, Tadashi Tai

Brain Research Protocols 2(4) 299-305 1998年6月
On the specificity of anti-sulfoglucuronosyl glycolipid antibodies

Akira Tokuda, Toshio Ariga, Yukihiro Isogai, Shiro Komba, Makoto Kiso, Akira Hasegawa, Tadashi Tai, Robert K. Yu

Journal of Carbohydrate Chemistry 17(4-5) 535-546 1998年
Accumulation of cholesterol and G(M2) ganglioside in cells cultured in the presence of progesterone: An implication for the basic defect in Niemann-Pick disease type C

Masahiro Sato, Shinjiro Akaboshi, Tetsuo Katsumoto, Miyako Taniguchi, Katsumi Higaki, Tadashi Tai, Hitoshi Sakuraba, Kousaku Ohno

Brain and Development 20(1) 50-52 1998年1月
Immunocytochemical detection of accumulated substrates in cultured fibroblasts from patients with the infantile and adult forms of Sandhoff disease

Hitoshi Sakuraba, Kohji Itoh, Yoko Kuroki, Ryoichi Kase, Michie Shimmoto, Kouichi Utsumi, Hideki Ozawa, Tadashi Tai, Akio Hara, Eiichiro Uyama

Clinica Chimica Acta 265(2) 263-266 1997年9月30日
Generation and characterization of mouse monoclonal antibodies specific for N-linked neutral oligosaccharides of glycoproteins

Hideki Ozawa, Katsuko Yamashita, Hitoshi Sakuraba, Kohji Itoh, Ryoichi Kase, Tadashi Tai

Archives of Biochemistry and Biophysics 342(1) 48-57 1997年6月1日
Gangliosides involved in activation of rat T lineage cells

Keiko Nohara, Hideki Ozawa, Tadashi Tai, Hikaru Saji, Hidekazu Fujimaki

Biochimica et Biophysica Acta - Lipids and Lipid Metabolism 1345(2) 207-214 1997年4月1日
Inhibition of highly metastatic FBJ-LL cell migration by ganglioside GD1a highly expressed in poorly metastatic FBJ-S1 cells

Sumiko Hyuga, Sadako Yamagata, Tadashi Tai, Tatsuya Yamagata

Biochemical and Biophysical Research Communications 231(2) 340-343 1997年2月13日
Immunohistochemical study of sulfatide expression in gastric carcinoma: Alteration of sulfatide expression

Hiroyuki Osawa, Kentaro Sugano, Toru Igari, Tadashi Tai, Masao Iwamori, Masanobu Kawakami

Journal of Clinical Gastroenterology 25(1) S135-S140 1997年
Changes in composition of newly synthesized sphingolipids of HeLa cells during the cell cycle. Suppression of sphingomyelin and higher-glycosphingolipid synthesis and accumulation of ceramide and glucosylceramide in mitotic cells

Kazuaki Yokoyama, Minoru Suzuki, Ikuo Kawashima, Ken Karasawa, Shoshichi Nojima, Takemi Enomoto, Tadashi Tai, Akemi Suzuki, Morio Setaka

European Journal of Biochemistry 249(2) 450-455 1997年
Immunocytochemical analysis of gangliosides in rat primary cerebellar cultures using specific monoclonal antibodies

Ikuo Kawashima, Isao Nagata, Tadashi Tai

Brain Research 732(1-2) 75-86 1996年9月2日
Cloning and expression of cDNA for O-acetylation of GD3 ganglioside

Kiyoshi Ogura, Kiyomitsu Nara, Yumiko Watanabe, Kenji Kohno, Tadashi Tai, Yutaka Sanai

Biochemical and Biophysical Research Communications 225(3) 932-938 1996年8月23日
Generation and characterization of anti-sulfoglucuronosyl paragloboside monoclonal antibody NGR50 and its immunoreactivity with peripheral nerve

M. Yamawaki, T. Ariga, J. W. Bigbee, H. Ozawa, I. Kawashima, T. Tai, T. Kanda, R. K. Yu

Journal of Neuroscience Research 44(6) 586-593 1996年6月15日
Differential expression of gangliosides and galactolipids in fetal human oligodendrocytes and astrocytes in culture

Jun-Ichi Satoh, Tadashi Tai, Seung U. Kim

Developmental Brain Research 93(1-2) 172-181 1996年5月31日
Distinctive ganglioside patterns revealed by anti-ganglioside antibody binding to differentiating CG-4 oligodendrocytes

Ronald L. Schnaar, Patti Longo, Lynda J.-S. Yang, Tadashi Tai

Glycobiology 6(3) 257-263 1996年4月
Ganglioside composition of the rat choriocarcinoma cell line, Rcho-1

Takamitsu Shirai, Saki Itonori, Tadashi Tai, Michael J. Soares, Kunio Shiota, Tomoya Ogawa

Glycoconjugate Journal 13(3) 415-421 1996年
Expression and localization of Lewisx glycolipids and GD1a ganglioside in human glioma cells

Toshio Ariga, Shama Bhat, Takashi Kanda, Masanaga Yamawaki, Tadashi Tai, Yasunori Kushi, Takeshi Kasama, Shizuo Handa, Robert K. Yu

Glycoconjugate Journal 13(2) 135-145 1996年
Accumulation of GM2 ganglioside in Niemann-Pick disease type C fibroblasts

Tamami Yano, Miyako Taniguchi, Shinjiro Akaboshi, Marie-Thèrése Vanier, Tadashi Tai, Hitoshi Sakuraba, Kousaku Ohno

Proceedings of the Japan Academy Series B: Physical and Biological Sciences 72(10) 214-219 1996年

もっとみる

書籍等出版物

糖鎖抗体を用いる実験法:動物細胞発現クローニング法によるガラクトシルセラミド発現因子cDNAの単離. 第5巻、脂質・糖質・複合糖質、基礎生化学実験法（日本生化学会編）
アスパラギン結合糖鎖の代表的な構造決定例. 続生化学実験講座、第4巻、複合糖質研究法Ｉ

182-194、東京化学同人、1985
抽出・精製・分析,溶媒抽出.新基礎生化学実験法

31-38,丸善,1988
ガングリオシド抗体の治療への応用.ガングリオシド研究法11

225-230,学会出版センター,1995
ガングリオシド抗体の作製法.ガングリオシ

211-215,学会出版センター,1995
モノクローナル抗体は糖鎖を分子認識する.糖鎖(永井克孝監修),第3巻,

78-84,東京化学同人,1994

所属学協会

共同研究・競争的資金等の研究課題

複合糖質の構造と機能

2002年 - 2007年
Structure and function of glycoconjugates