TAGAWA Masatoshi

J-GLOBAL         Last updated: Jan 1, 2019 at 11:54
 
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Name
TAGAWA Masatoshi
Affiliation
Chiba Cancer Center (Research Institute)
Section
Division of Pathology and Cell Therapy
Job title
Head
Degree
M.D. & Ph.D(Chiba University)

Research Areas

 

Academic & Professional Experience

 
Apr 1997
 - 
Today
Head, Division of Pathology and Cell Therapy, Chiba Cancer Center Res Inst
 
Feb 2003
 - 
Today
Visiting Professor, 4th Hospital, Hebei Medical University
 
Apr 2005
 - 
Today
Professor, Department of Molecular Biology and Oncology, Graduate School of Chiba University
 
Mar 2010
 - 
Mar 2014
Visiting Professor, Shenyang Pharmaceutical University
 

Education

 
 
 - 
1984
Immunology, Graduate School, Chiba University
 
 
 - 
1979
Faculty of Medicine, Chiba University
 

Committee Memberships

 
 
   
 
International Society of Cell and Gene Therapy of Cancer  Council
 
 
   
 
Japan Society of Gene Therapy  Council
 

Published Papers

 
Ushigome M, Nabeya Y, Soda H, Takiguchi N, Kuwajima A, Tagawa M, Matsushita K, Koike J, Funahashi K, Shimada H
International journal of clinical oncology   23(5) 917-923   Oct 2018   [Refereed]
Kubo S, Takagi-Kimura M, Tagawa M, Kasahara N
Cancer gene therapy      Oct 2018   [Refereed]
Morinaga T, Yamaguchi N, Nakayama Y, Tagawa M, Yamaguchi N
International journal of molecular sciences   19(6) 1811   Jun 2018   [Refereed]
Chai K, Ning X, Nguyễn TTT, Zhong B, Morinaga T, Li Z, Shingyoji M, Tada Y, Tatsumi K, Shimada H, Hiroshima K, Yamaguchi N, Tagawa M
Oncotarget   9(40) 26130-26143   May 2018   [Refereed]
Morinaga T, Nguyễn TTT, Zhong B, Hanazono M, Shingyoji M, Sekine I, Tada Y, Tatsumi K, Shimada H, Hiroshima K, Tagawa M
Virology journal   14(1) 219   Nov 2017   [Refereed]
Yamamoto Y, Nagasato M, Rin Y, Henmi M, Ino Y, Yachida S, Ohki R, Hiraoka N, Tagawa M, Aoki K
Cancer medicine   6(10) 2385-2397   Oct 2017   [Refereed]
Yamauchi S, Zhong B, Kawamura K, Yang S, Kubo S, Shingyoji M, Sekine I, Tada Y, Tatsumi K, Shimada H, Hiroshima K, Tagawa M
BMC cancer   17(1) 622   Sep 2017   [Refereed]
Nagasato M, Rin Y, Yamamoto Y, Henmi M, Hiraoka N, Chiwaki F, Matsusaki K, Tagawa M, Sasaki H, Aoki K
Anticancer research   37(7) 3599-3605   Jul 2017   [Refereed]
Shimazu K, Tada Y, Morinaga T, Shingyoji M, Sekine I, Shimada H, Hiroshima K, Namiki T, Tatsumi K, Tagawa M
BMC cancer   17(1) 309   May 2017   [Refereed]
Hoshino I, Nagata M, Takiguchi N, Nabeya Y, Ikeda A, Yokoi S, Kuwajima A, Tagawa M, Matsushita K, Satoshi Y, Hideaki S
Cancer science   108(3) 308-315   Mar 2017   [Refereed]
Ak G, Tada Y, Shimada H, Metintas S, Ito M, Hiroshima K, Tagawa M, Metintas M
BMC cancer   17(1) 212   Mar 2017   [Refereed]
Wu D, Hiroshima K, Yusa T, Ozaki D, Koh E, Sekine Y, Matsumoto S, Nabeshima K, Sato A, Tsujimura T, Yamakawa H, Tada Y, Shimada H, Tagawa M
Annals of diagnostic pathology   26 31-37   Feb 2017   [Refereed]
Qin Y, Sekine I, Fan M, Takiguchi Y, Tada Y, Shingyoji M, Hanazono M, Yamaguchi N, Tagawa M
Cancer cell international   17 120   2017   [Refereed]
Sheikh A, Takatori A, Hossain MS, Hasan MK, Tagawa M, Nagase H, Nakagawara A
Cancer science   107(9) 1223-1232   Sep 2016   [Refereed]
Hiroshima K, Wu D, Hasegawa M, Koh E, Sekine Y, Ozaki D, Yusa T, Walts AE, Marchevsky AM, Nabeshima K, Tada Y, Shimada H, Tagawa M
Diagnostic cytopathology   44(7) 591-598   Jul 2016   [Refereed]
Jiang Y, Zhong B, Kawamura K, Morinaga T, Shingyoji M, Sekine I, Tada Y, Tatsumi K, Shimada H, Hiroshima K, Tagawa M
BMC cancer   16 455   Jul 2016   [Refereed]
Oshima Y, Shimada H, Yajima S, Nanami T, Matsushita K, Nomura F, Kainuma O, Takiguchi N, Soda H, Ueda T, Iizasa T, Yamamoto N, Yamamoto H, Nagata M, Yokoi S, Tagawa M, Ohtsuka S, Kuwajima A, Murakami A, Kaneko H
Journal of gastroenterology   51(1) 30-34   Jan 2016   [Refereed]
Oshima Y, Shimada H, Yajima S, Nanami T, Matsushita K, Nomura F, Kainuma O, Takiguchi N, Soda H, Ueda T, Iizasa T, Yamamoto N, Yamamoto H, Nagata M, Yokoi S, Tagawa M, Ohtsuka S, Kuwajima A, Murakami A, Kaneko H
Journal of gastroenterology   51(1) 83   Jan 2016   [Refereed]
Kawamura K, Wada A, Wang JY, Li Q, Ishii A, Tsujimura H, Takagi T, Itami M, Tada Y, Tatsumi K, Shimada H, Hiroshima K, Tagawa M
Journal of cancer research and clinical oncology   142(1) 27-36   Jan 2016   [Refereed]
Clinical significance of serum autoantibodies against Ras-like GTPases, RalA, in patients with esophageal squamous cell carcinoma.
Nanami, T., Shimada, H., Yajima, S., Oshima, Y., Matsushita, K., Nomura, F., Nagata, M., Tagawa, M., Otsuka, S., Kuwajima, A. and Kaneko, H.
Esophagus   13 167-172   2016   [Refereed]
Anti-tumor immunity elicited by direct intratumoral administration of a recombinant adenovirus expressing either IL-28A/IFN-λ2 or IL-29/IFN-λ1
Hasegawa, K., Tagawa, M., Takagi, K., Tsukamoto, H., Tomioka, Y., Suzuki, T., Nishioka, Y., Ohrui, T. and Numasaki, M
Cancer Gene Ther   23 266-277   2016   [Refereed]
Tada Y, Hiroshima K, Shimada H, Shingyoji M, Suzuki T, Umezawa H, Sekine I, Takiguchi Y, Tatsumi K, Tagawa M
SpringerPlus   5 195   2016   [Refereed]
Yamauchi S, Kawamura K, Okamoto S, Morinaga T, Jiang Y, Shingyoji M, Sekine I, Kubo S, Tada Y, Tatsumi K, Shimada H, Hiroshima K, Tagawa M
Apoptosis   20(12) 1587-1598   Dec 2015   [Refereed]
Ma G, Zhong B, Okamoto S, Jiang Y, Kawamura K, Liu H, Li Q, Shingyoji M, Sekine I, Tada Y, Tatsumi K, Shimada H, Hiroshima K, Tagawa M
Tumour biology   36(10) 8137-8145   Sep 2015   [Refereed]
Yang S, Kawamura K, Okamoto S, Yamauchi S, Shingyoji M, Sekine I, Kobayashi H, Tada Y, Tatsumi K, Hiroshima K, Shimada H, Tagawa M
BMC cancer   15 464   Jun 2015   [Refereed]
Administration of DNA encoding the interleukin-27 gene augments antitumor responses through non-adaptive immunity.
Li, Q., Sato, A., Shimozato, O., Shingyoji, M., Tada, Y., Tatsumi, K., Shimada, H., Hiroshima, K. and Tagawa, M.
Scand J Immunol.   82 320-327   2015   [Refereed]
Expression of p53 synergistically augments caspases-mediated apoptosis induced by replication-competent adenoviruses in pancreatic carcinoma cells.
Takei, Y., Okamoto, S., Kawamura, K., Jiang, Y., Morinaga, T., Shingyoji, M., Sekine, I., Kubo, S., Tada, Y., Tatsumi, K., Shimada, H., Hiroshima, K., Yamaguchi, N. and Tagawa, M
Cancer Gene Ther.   22 445-453   2015   [Refereed]
Molecular-targeted therapy for malignant mesothelioma.
Tada, Y., Suzuki, T., Shimada, H., Hiroshima, K., Tatsumi, K. and Tagawa, M
Pleura   1-11   2015   [Refereed]
Zhong B, Ma G, Sato A, Shimozato O, Liu H, Li Q, Shingyoji M, Tada Y, Tatsumi K, Shimada H, Hiroshima K, Tagawa M
Journal of immunology research   2015 743828   2015   [Refereed]
Tada Y, Hiroshima K, Shimada H, Morishita N, Shirakawa T, Matsumoto K, Shingyoji M, Sekine I, Tatsumi K, Tagawa M
SpringerPlus   4 358   2015   [Refereed]
Fukamachi T, Ikeda S, Saito H, Tagawa M, Kobayashi H
Molecular and clinical oncology   2(6) 1160-1166   Nov 2014   [Refereed]
Yamamoto Y, Hiraoka N, Goto N, Rin Y, Miura K, Narumi K, Uchida H, Tagawa M, Aoki K
Journal of Controlled Release   192 284-293   Oct 2014   [Refereed]
Suzuki T, Kawamura K, Li Q, Okamoto S, Tada Y, Tatsumi K, Shimada H, Hiroshima K, Yamaguchi N, Tagawa M
BMC cancer   14 713   Sep 2014   [Refereed]
Combination of adenoviruses expressing melanoma differentiation-associated gene-7 and chemotherapeutic agents produces enhanced cytotoxicity on esophageal carcinoma.
Ma, G., Kawamura, K., Yang, S., Okamoto, S., Li, Q., Namba, M., Shingyoji, M., Tada, Y., Tatsumi, K., Hiroshima, K., Shimada, H. and Tagawa, M
Cancer Gene Ther.   21 31-37   2014   [Refereed]
Gene therapy in malignant pleural mesothelioma.
Tagawa, M
Lung Cancer Manage.   3 29-33   2014   [Refereed]
Oncolytic virotherapy for osteosarcoma using midkine promoter-regulated adenoviruses.
Takagi-Kimura, M., Yamano, T., Tagawa, M. and Kubo S
Cancer Gene Ther.   21 126-132   2014   [Refereed]
Enhanced expression of the 4-galactosyltransferase 2 gene impairs the mammalian tumor growth.
Tagawa, M., Shirane, K., Yu, L., Sato, T., Furukawa, S., Mizuguchi, H., Kuji, R., Kawamura, K., Takahashi, N., Kato, K., Hayakawa, S., Sawada, S. and Furukawa, K.
Cancer Gene Ther.   21 219-227   2014   [Refereed]
Zoledronic acid induces apoptosis and S-phase arrest in mesothelioma through inhibiting Rab family proteins and topoisomerase II actions.
Okamoto, S., Jiang, Y., Kawamura, K., Shingyoji, M., Tada, Y., Sekine, I., Takiguchi, Y., Tatsumi, K., Kobayashi, H., Shimada, H., Hiroshima, K. and Tagawa, M.
Cell Death Dis.   5 e1517   2014   [Refereed]
Takagi-Kimura M, Yamano T, Tamamoto A, Okamura N, Okamura H, Hashimoto-Tamaoki T, Tagawa M, Kasahara N, Kubo S
Cancer science   104(11) 1433-1439   Nov 2013   [Refereed]
Kawamura K, Hiroshima K, Suzuki T, Chai K, Yamaguchi N, Shingyoji M, Yusa T, Tada Y, Takiguchi Y, Tatsumi K, Shimada H, Tagawa M
American journal of clinical pathology   140(4) 544-549   Oct 2013   [Refereed]
Novel type III interferons produce anti-tumor effects through multiple functions.
Li Q, Kawamura K, Tada Y, Shimada H, Hiroshima K, Tagawa M
Frontiers in bioscience (Landmark edition)   18 909-918   Jun 2013   [Refereed]
Gotoh A, Nagaya H, Kanno T, Tagawa M, Nishizaki T
Urology   81(4) 920.e7-11   Apr 2013   [Refereed]
Fukamachi T, Ikeda S, Wang X, Saito H, Tagawa M, Kobayashi H
Genes   4(1) 65-85   Mar 2013   [Refereed]
Wu D, Hiroshima K, Matsumoto S, Nabeshima K, Yusa T, Ozaki D, Fujino M, Yamakawa H, Nakatani Y, Tada Y, Shimada H, Tagawa M
American journal of clinical pathology   139(1) 39-46   Jan 2013   [Refereed]
Gene therapy for malignant mesothelioma: Current prospects and challenges.
Tagawa, M., Tada, Y., Shimada, H. and Hiroshima, K.
Cancer Gene Ther.   20 150-156   2013   [Refereed]
Heat-shock protein 90 inhibitors synergistically enhance melanoma differentiation-associated gene-7-mediated cell killing of human pancreatic carcinoma.
Zhang, M., Kawamura, K., Jiang, Y., Shingyoji, M., Ma, G., Li, Q., Hu, J., Qi, Y., Liu, H., Zhang, F., Kang, S., Shan, B., Wang, S., Chada, S. and Tagawa, M
Cancer Gene Ther.   20 663-670   2013   [Refereed]
Tada Y, Shimada H, Hiroshima K, Tagawa M
BioMed research international   2013 572609   2013   [Refereed]
Okamoto S, Jiang Y, Kawamura K, Shingyoji M, Fukamachi T, Tada Y, Takiguchi Y, Tatsumi K, Shimada H, Hiroshima K, Kobayashi H, Tagawa M
PloS one   8(3) e60297   2013   [Refereed]
Li Q, Kawamura K, Yang S, Okamoto S, Kobayashi H, Tada Y, Sekine I, Takiguchi Y, Shingyouji M, Tatsumi K, Shimada H, Hiroshima K, Tagawa M
PloS one   8(8) e72709   2013   [Refereed]
Yamanaka M, Tada Y, Kawamura K, Li Q, Okamoto S, Chai K, Yokoi S, Liang M, Fukamachi T, Kobayashi H, Yamaguchi N, Kitamura A, Shimada H, Hiroshima K, Takiguchi Y, Tatsumi K, Tagawa M
Journal of Thoracic Oncology   7(12) 1850-1857   Dec 2012   [Refereed]
Beneficial oncolytic effect of fiber-substituted conditionally replicating adenovirus on human lung cancer.
Kanno T, Gotoh A, Nakano T, Tagawa M, Nishizaki T
Anticancer research   32(11) 4891-4895   Nov 2012   [Refereed]
Gene therapy using adenovirus against malignant mesothelioma.
Gotoh A, Kanno T, Nagaya H, Nakano T, Tabata C, Fukuoka K, Tagawa M, Nishizaki T
Anticancer research   32(9) 3743-3747   Sep 2012   [Refereed]
Kitazono-Saitoh M, Takiguchi Y, Kitazono S, Ashinuma H, Kitamura A, Tada Y, Kurosu K, Sakaida E, Sekine I, Tanabe N, Tagawa M, Tatsumi K
Oncology reports   28(1) 33-40   Jul 2012   [Refereed]
Fiber-substituted conditionally replicating adenovirus for oncolysis of human renal carcinoma cells.
Nagaya H, Tagawa M, Hiwasa K, Terao S, Kanno T, Nishizaki T, Gotoh A
Anticancer research   32(7) 2985-2989   Jul 2012   [Refereed]
Okamoto S, Kawamura K, Li Q, Yamanaka M, Yang S, Fukamachi T, Tada Y, Tatsumi K, Shimada H, Hiroshima K, Kobayashi H, Tagawa M
Journal of thoracic oncology   7(5) 873-882   May 2012   [Refereed]
Hamada K, Yoshihara C, Ito T, Tani K, Tagawa M, Sakuragawa N, Itoh H, Koyama Y
Journal of Gene Medicine   14(2) 120-127   Feb 2012   [Refereed]
Nagakawa H, Shimozato O, Yu L, Wada A, Kawamura K, Li Q, Chada S, Tada Y, Takiguchi Y, Tatsumi K, Tagawa M
Cellular immunology   275(1-2) 90-97   Jan 2012   [Refereed]
Impact of serum biomarkers on esophageal squamous cell carcinoma.
Shimada, H., Yajima, S., Oshima, Y., Hiwasa, T., Tagawa, M., Matsushita, K. and Nomura, F
Esophagus   9 131-140   2012   [Refereed]
Upregulated p53 expression activates apoptotic pathways in wild-type p53-bearing mesothelioma and enhances cytotoxicity of cisplatin and pemetrexed.
Li, Q., Kawamura, K., Okamoto, S., Yamanaka, M., Yang, S., Yamauchi, S., Fukamachi, T., Kobayashi, H., Tada, Y., Takiguchi, Y., Tatsumi, K., Shimada, H., Hiroshima, K. and Tagawa, M
Cancer Gene Ther.   19 218-228   2012   [Refereed]
Efficient antitumor effects of carrier cells loaded with a fiber-substituted conditionally replicating adenovirus on CAR-negative tumor cells.
Iguchi, K., Sakurai, F., Tomita, K., Katayama, K., Yamaguchi, T., Tagawa, M., Kawabata, M., Shirakawa, T. and Mizuguchi, H
Cancer Gene Ther.   19 118-125   2012   [Refereed]
Fujie H, Tanaka T, Tagawa M, Kaijun N, Watanabe M, Suzuki T, Nakayama K, Numasaki M
Cancer science   102(11) 1977-1990   Nov 2011   [Refereed]
[Recent advancement of esophageal cancer gene therapy].
Yajima S, Oshima Y, Shimada H, Matsushita K, Tagawa M
Nihon rinsho. Japanese journal of clinical medicine   69 Suppl 6 387-391   Aug 2011   [Refereed]
Kitamura A, Matsushita K, Takiguchi Y, Shimada H, Tada Y, Yamanaka M, Hiroshima K, Tagawa M, Tomonaga T, Matsubara H, Inoue M, Hasegawa M, Sato Y, Levens D, Tatsumi K, Nomura F
Cancer science   102(7) 1366-1373   Jul 2011   [Refereed]
Tagawa M, Kawamura K, Li Q, Tada Y, Hiroshima K, Shimada H
Clinical & developmental immunology   2011(479013) 1-6   2011   [Refereed]
Adenoviruses-mediated transduction of human oesophageal carcinoma cells with the interferon-λ genes produced anti-tumor effects.
Li, Q., Kawamura, K., Okamoto, S., Fujie, H., Numasaki, M., Namba, M., Nagata, M., Shimada, H., Kobayashi,, H. and Tagawa, M
Br. J. Cancer.   (105) 1302-1312   2011   [Refereed]
Angiogenesis-related factors are molecular targets for diagnosis and treatment of patients with esophageal carcinoma.
Oshima Y, Yajima S, Yamazaki K, Matsushita K, Tagawa M, Shimada H
Annals of Thoracic and Cardiovascular Surgery   16(6) 389-393   Dec 2010   [Refereed]
Fukamachi T, Chiba Y, Wang X, Saito H, Tagawa M, Kobayashi H
Cancer letters   297(2) 182-189   Nov 2010   [Refereed]
Kubo S, Kawasaki Y, Yamaoka N, Tagawa M, Kasahara N, Terada N, Okamura H
Journal of Gene Medicine   12(8) 681-692   Aug 2010   [Refereed]
Li, Q., Kawamura, K., Ma, G., Iwata, F., Numasaki, M., Suzuki, N., Shimada, H. and Tagawa, M.
Eur. J. Cancer   46(1) 180-190   2010
Combinatory cytotoxic effects produced by E1B-55kDa-deleted adenoviruses and chemotherapeutic agents are dependent on the agents in esophageal carcinoma.
Ma, G., Kawamura, K., Li, Q., Okamoto, S., Suzuki, N., Kobayashi, H., Liang, M., Tada, Y., Tatsumi, K., Hiroshima, K., Shimada, H. and Tagawa, M.
Cancer Gene Ther.   17 803-813   2010   [Refereed]
Gene medicine for cancer treatment: commercially available medicine and accumulated clinical data in China.
Ma G, Shimada H, Hiroshima K, Tada Y, Suzuki N, Tagawa M
Drug Design, Development and Therapy   2 115-122   Feb 2009   [Refereed]
Shimozato, O., Sato, A., Kawamura, K., Chiyo, M., Ma, G., Li, Q. and Tagawa, M.
Immunology   128 e816-e825   2009
Ma, G., Kawamura, K., Li, Q., Suzuki, N., Liang, M., Namba, M., Shimada, H. and Tagawa, M
Cancer Gene Ther.   16(11) 832-840   2009
[Enhanced expression of CD40L cDNA on ovarian cancer cell line OVHM induces the secretion of Th1 cytokines from dendritic cells].
Zhang ZM, Zhang FH, Wang XM, Zhang C, Liu J, Gu LM, Li QH, Shan BE, Tagawa M
Zhonghua zhong liu za zhi [Chinese journal of oncology]   30(3) 174-178   Mar 2008   [Refereed]
Tagawa, M., Kawamura, K., Ueyama, T., Nakamura, M., Tada, Y., Ma, G., Li, Q., Suzuki, N., Shimada, H., Kuriyama, T. and Ochiai, T
Front. Biosci.   13 2578-2587   2008
Recent advances in esophageal cancer gene therapy.
Shimada, H., Matsushita, K and Tagawa, M
Ann. Thorac. Cardiovasc. Surg.   14 3-8   2008
Liu, L., Wang, S., Shan, B., Shao, L., Sato, A., Kawamura, K., Li, Q., Ma, G. and Tagawa, M
Scand. J. Immunol.   68 22-29   2008
Ouchida, R., Yamasaki, S., Hikida, M., Masuda, K., Kawamura, K., Wada, A., Mochizuki, S., Tagawa, M., Sakamoto, A., Hatano, M., Tokuhisa, T., Koseki, H., Saito, T., Kurosaki, T. and Ji-Yang Wang
Immunity   29(1) 33-43   2008
Ouchida, R., Ukai, A., Mori, H., Kawamura, K., Dollé, E. T. M., Tagawa, M., Sakamoto, A., Tokuhisa, T., Yokosuka, T., Saito, T., Yokoi, M., Hanaoka, F., Vijg, J. and Ji-Yang Wang
DNA Repair   7(8) 1392-1398   2008
Gene medicine for cancer treatment: Commercially available medicine and accumulated clinical data in China.
Ma, G., Shimada, H., Hiroshima, K., Tada, Y., Suzuki, N. and Tagawa, M
Drug Des. Devel. Ther.   2 115-122   2008
Adenovirus vectors with chimeric type 5 and 35 fiber proteins exhibit enhanced transfection of human pancreatic cancer cells.
Int. J. Oncol.   33 1141-1147   2008
Toyoda, E., Doi, R., Kami, K., Mori, T., Ito, D., Koizumi, M., Kida, A., Nagai, K., Ito, T., Masui, T., Wada, M., Tagawa, M. and Uemoto, S
J. Exp. Clin. Cancer Res.   27 30   2008
Tada, Y., Takiguchi, Y., Hiroshima, K., Shimada, H., Ueyama, T., Nakamura, M., Tatsumi, K., Kuriyama, T. and Tagawa, M
Oncol. Res.   17 239-246   2008
Gene therapy for malignant pleural mesothelioma: present and future.
Tada Y, Takiguchi Y, Hiroshima K, Shimada H, Ueyama T, Nakamura M, Tatsumi K, Kuriyama T, Tagawa M
Oncology research   17(6) 239-246   2008   [Refereed]
Adenovirus type 5 substituted with type 11 or 35 fiber structure increases its infectivity to human cells enabling dual gene transfer in CD46-dependent and -independent manners.
Yu L, Shimozato O, Li Q, Kawamura K, Ma G, Namba M, Ogawa T, Kaiho I, Tagawa M
Anticancer research   27(4B) 2311-2316   Jul 2007   [Refereed]
Wada, A., Tada, Y., Kawamura, K., Takiguchi, Y., Tatsumi, K., Kuriyama, T., Takenouchi, T., O-Wang, J., and Tagawa, M
Cancer Gene Ther.   14 262-267   2007
Transcriptional regulatory regions of the survivin gene activate an exogenous suicide gene in human tumors and enhance the sensitivity to a prodrug.
Kawamura, K., Yu, L., Tomizawa, M., Shimozato, O., Ma, G., Li, Q., Sato, A., Yang, Y., Suzuki, T., Abdel-Azizi, N. M., Tagawa, M
Anticancer Res.   27 89-94   2007
IL-28 elicits antitumor responses against murine fibrosarcoma.
Numasaki, M., Tagawa, M., Hidaka, M., Suzuki, T., Nakamura, A., Okada, M., Iwakura, Y., Aiba, S. and Yamaya, M
J. Immunol.   178 5086-5098   2007
Hamada, K., Desaki, J., Nakagawa, K., Zhang, T., Shirakawa, T., Gotoh, A. and Tagawa, M.
Mol. Ther.   15 1121-1128   2007
Adenovirus type 5 substituted with type 11 or type 35 fiber structure increases its infectivity to human cells and enables dual gene transfer in CD46-dependent and -independent manners.
Yu, L., Shimozato, O., Li, Q., Kawamura, K., Ma, G., Namba, M., Ogawa, T., Kaiho, I. and Tagawa, M
Anticancer Res.   27 2311-2316   2007
Terao, S., Shirakawa, T., Kubo, S., Bishunu, A., Lee, S-J., Goda, K., Tsukuda, M., Hamada, K., Tagawa, M., Takenaka, A., Fujisawa, M. and Gotoh, A.
Urology   70 1009-1013   2007
Are novel interferon-lambdas promising anti-viral cytokines?
Li, Q and Tagawa, M
Curr. Trend. Immunol.   8 53-60   2007
Tagawa M, Kawamura K, Shimozato O, Ma G, Li Q, Suzuki N, Shimada H, Ochiai T
Cancer Immunology, Immunotherapy   55(11) 1420-1425   Nov 2006   [Refereed]
Up-regulated expression of the uridine phosphorylase gene in human gastric tumors is correlated with a favorable prognosis.
Kawamura K, Takiguchi N, Wada A, Takenobu H, Kimura H, Soda H, Nagata M, Asano T, Tagawa M
Anticancer research   26(6C) 4647-4651   Nov 2006   [Refereed]
[Biological and antitumor effects of CD40L on ovarian cancer cell line OVHM].
Zhang ZM, Zhang C, Zhang FH, Shan BE, Nakagawn S, Tagawa M
Ai zheng = Aizheng = Chinese journal of cancer   25(9) 1102-1107   Sep 2006   [Refereed]
Ukai A, Maruyama T, Mochizuki S, Ouchida R, Masuda K, Kawamura K, Tagawa M, Kinoshita K, Sakamoto A, Tokuhisa T, O-Wang J
Genes to Cells   11(2) 111-121   Feb 2006   [Refereed]
Antitumor activity and immune enhancement of murine interleukin-23 expressed in murine colon carcinoma cells.
Shan BE, Hao JS, Li QX, Tagawa M
Cellular & Molecular Immunology   3(1) 47-52   Feb 2006   [Refereed]
Shimozato O, Ugai S, Chiyo M, Takenobu H, Nagakawa H, Wada A, Kawamura K, Yamamoto H, Tagawa M
Immunology   117(1) 22-28   Jan 2006   [Refereed]
Increased infectivity of adenovirus type 5 bearing type 11 or type 35 fibers to human esophageal and oral carcinoma cells.
Yu L, Takenobu H, Shimozato O, Kawamura K, Nimura Y, Seki N, Uzawa K, Tanzawa H, Shimada H, Ochiai T, Tagawa M
Oncology reports   14(4) 831-835   Oct 2005   [Refereed]
Nezu M, Tomonaga T, Sakai C, Ishii A, Itoga S, Nishimura M, Matsuo Y, Tagawa M, Nomura F
Biochem Biophys Res Comm   335(3) 843-849   Sep 2005   [Refereed]

Books etc

 
Cancer Gene Therapy 2010
Research Signpost   2010   
Gene Therapy 2007
Medical View   2007   
Unlization of the promoter region of the midkine gene as a tool to drive the therapeutic genes in a tumor specific manner.
Adv.Enzyme Regul.   2003   
An antigen-specific suppressor T cell factor composed of two distict polypeptide chain.In: Humoral factors in host defence.
Academic Press, p.71-79, 1983.   
Antigen-specific suppressor T cell factor:Functional and molecular structure.In:T cell hybridomas.ed.by Taussig, M.J.
CRC Press, p.197-208, 1985.   
Characterization of mouse melanoma associate antigen and genomic cloning.In: Gann monograph on cancer research on cellular and molecular mechanisms of tumor immunity. 34 ed. by Hashimoto, Y. and Hamaoka, T. J.
J.Cancer Assoc. p51-58, 1988.   
Cloning, sequencing and differential splicing of the Lyt-2 gene. In: New horizons in animal models for autoimmune disease. ed. Kyogoku M.and Wigzel H.
Academic Press (Tokyo), p133-140, 1987.   
Identification of a receptor-type tyrosine phosphatase expressed in postmitotic maturing neurons: its structure and expression in the central nervous system. In: Kinases and phosphatases in lymphocyte and neuron signaling. ed. by Yakura, H.
Springer-Vertag Tokyo, p.308-309, 1997.   
Suppressor T-cell hybridoma with a receptor recognizing KLH-specific suppressor factor. In: The biology of idiotypes. ed. by Green, M.I. and Nisonoff, A.
Plenum Press, p435-447, 1984.   

Research Grants & Projects

 
2.Molecular mechanism of responses
Grant-in-Aid for Scientific Research
Project Year: 1997 - 2017
1.Cancer gene therapy
Grant-in-Aid for Scientific Research
Project Year: 1997 - 2017

Patents

 
特許US 7,030,099 B2 : Tumor specific promoters of the midkine gene that allow for selective expression in p53-inactivated cells
US 7,030,099 B2

Social Contribution

 
Biological Procedures Online
[Editor]  Springer Nature  Jul 2014 - Today
Biomarkers in Cancer
[Editor]  Libertas Academica  Jul 2012 - Today
Cancer Gene Therapy
[Editor]  Springer Nature  Apr 2006 - Today