田中啓二 (Keiji Tanaka) - 論文

Changes in brain proteasome dynamics associated with aging

Nodoka Nago, Shigeo Murata, Keiji Tanaka, Nobuyuki Tanahashi

Genes to Cells 2024年3月25日

cIAP1-based degraders induce degradation via branched ubiquitin architectures.

Yoshino Akizuki, Mai Morita, Yuki Mori, Ai Kaiho-Soma, Shivani Dixit, Akinori Endo, Marie Shimogawa, Gosuke Hayashi, Mikihiko Naito, Akimitsu Okamoto …

Nature chemical biology 19(3) 311-322 2022年10月31日

The TGN/EE SNARE protein SYP61 and the ubiquitin ligase ATL31 cooperatively regulate plant responses to carbon/nitrogen conditions in Arabidopsis.

Yoko Hasegawa, Thais Huarancca Reyes, Tomohiro Uemura, Anirban Baral, Akari Fujimaki, Yongming Luo, Yoshie Morita, Yasushi Saeki, Shugo Maekawa, Shigetaka Yasuda …

The Plant cell 34(4) 1354-1374 2022年3月29日

Unfolding is the driving force for mitochondrial import and degradation of the Parkinson's disease-related protein DJ-1

Bruno Barros Queliconi, Waka Kojima, Mayumi Kimura, Kenichiro Imai, Chisato Udagawa, Chie Motono, Takatsugu Hirokawa, Shinya Tashiro, Jose M. M. Caaveiro, Kouhei Tsumoto …

Journal of Cell Science 134(22) 2021年11月15日

Loss of peptide:N-glycanase causes proteasome dysfunction mediated by a sugar-recognizing ubiquitin ligase.

Yukiko Yoshida, Makoto Asahina, Arisa Murakami, Junko Kawawaki, Meari Yoshida, Reiko Fujinawa, Kazuhiro Iwai, Ryuichi Tozawa, Noriyuki Matsuda, Keiji Tanaka …

Proceedings of the National Academy of Sciences of the United States of America 118(27) 2021年7月6日

Multifaceted array-based keloidal gene expression profiling reveals specific MDFI upregulation in keloid lesions.

M Asai, Y Koike, Y Kuwatsuka, Y Yagi, K Kashiyama, K Tanaka, H Mishima, K Yoshiura, A Utani, H Murota

Clinical and experimental dermatology 46(7) 1255-1261 2021年4月26日

TRIP12 promotes small-molecule-induced degradation through K29/K48-branched ubiquitin chains.

Ai Kaiho-Soma, Yoshino Akizuki, Katsuhide Igarashi, Akinori Endo, Takuji Shoda, Yasuko Kawase, Yosuke Demizu, Mikihiko Naito, Yasushi Saeki, Keiji Tanaka …

Molecular cell 81(7) 1411-1424 2021年4月1日

Mammalian BCAS3 and C16orf70 associate with the phagophore assembly site in response to selective and non-selective autophagy.

Waka Kojima, Koji Yamano, Hidetaka Kosako, Kenichiro Imai, Reika Kikuchi, Keiji Tanaka, Noriyuki Matsuda

Autophagy 1-26 2021年1月26日

Ribosomal protein S7 ubiquitination during ER stress in yeast is associated with selective mRNA translation and stress outcome.

Yasuko Matsuki, Yoshitaka Matsuo, Yu Nakano, Shintaro Iwasaki, Hideyuki Yoko, Tsuyoshi Udagawa, Sihan Li, Yasushi Saeki, Tohru Yoshihisa, Keiji Tanaka …

Scientific reports 10(1) 19669-19669 2020年11月12日

A substrate-trapping strategy to find E3 ubiquitin ligase substrates identifies Parkin and TRIM28 targets.

Masashi Watanabe, Yasushi Saeki, Hidehisa Takahashi, Fumiaki Ohtake, Yukiko Yoshida, Yusuke Kasuga, Takeshi Kondo, Hiroaki Yaguchi, Masanobu Suzuki, Hiroki Ishida …

Communications biology 3(1) 592-592 2020年10月20日

Proteomic and metabolomic analyses uncover sex-specific regulatory pathways in mouse fetal germline differentiation

Hayashi, Y, Mori, M, Igarashi, K, Tanaka, K, Takehara, A, Ito-Matsuoka, Y, Kanai, A, Yaegashi, N, Soga, T, Matsui, Y

Biol. Reprod. 103(4) 717-735 2020年10月5日査読有り

Critical role of mitochondrial ubiquitination and the OPTN ATG9A axis in mitophagy

Koji Yamano, Reika Kikuchi, Waka Kojima, Ryota Hayashida, Fumika Koyano, Junko Kawawaki, Takuji Shoda, Yosuke Demizu, Mikihiko Naito, Keiji Tanaka …

Journal of Cell Biology 219(9) 2020年9月7日

Critical role of mitochondrial ubiquitination and the OPTN-ATG9A axis in mitophagy.

Koji Yamano, Reika Kikuchi, Waka Kojima, Ryota Hayashida, Fumika Koyano, Junko Kawawaki, Takuji Shoda, Yosuke Demizu, Mikihiko Naito, Keiji Tanaka …

The Journal of cell biology 219(9) 2020年9月7日査読有り

The HOIL-1L ligase modulates immune signalling and cell death via monoubiquitination of LUBAC.

Yasuhiro Fuseya, Hiroaki Fujita, Minsoo Kim, Fumiaki Ohtake, Akira Nishide, Katsuhiro Sasaki, Yasushi Saeki, Keiji Tanaka, Ryosuke Takahashi, Kazuhiro Iwai

Nature cell biology 22(6) 663-673 2020年6月査読有り

Molecular bases for HOIPINs-mediated inhibition of LUBAC and innate immune responses.

Oikawa D, Sato Y, Ohtake F, Komakura K, Hanada K, Sugawara K, Terawaki S, Mizukami Y, Phuong HT, Iio K …

Communications Biology 3(1) 163-163 2020年4月査読有り

Two distinct modes of DNMT1 recruitment ensure stable maintenance DNA methylation.

Atsuya Nishiyama, Christopher B Mulholland, Sebastian Bultmann, Satomi Kori, Akinori Endo, Yasushi Saeki, Weihua Qin, Carina Trummer, Yoshie Chiba, Haruka Yokoyama …

Nature communications 11(1) 1222-1222 2020年3月6日

【イメージング時代の構造生命科学細胞の動態、膜のないオルガネラ、分子の構造変化をトランススケールに観る】(第2章)構造生命科学からトランススケール・イメージングによる細胞動態学へトランススケールな解析が待たれる生命科学の未解決課題タンパク質のマルチバレント相互作用が駆動する液液相分離

安田さや香, 田中啓二, 佐伯泰

実験医学 38(5) 756-761 2020年3月

Stress- and ubiquitylation-dependent phase separation of the proteasome.

Sayaka Yasuda, Hikaru Tsuchiya, Ai Kaiho, Qiang Guo, Ken Ikeuchi, Akinori Endo, Naoko Arai, Fumiaki Ohtake, Shigeo Murata, Toshifumi Inada …

Nature 578(7794) 296-300 2020年2月5日査読有り

Structural insights into ubiquitin recognition and Ufd1 interaction of Npl4.

Yusuke Sato, Hikaru Tsuchiya, Atsushi Yamagata, Kei Okatsu, Keiji Tanaka, Yasushi Saeki, Shuya Fukai

Nature communications 10(1) 5708-5708 2019年12月13日査読有り

Loss of Parkin contributes to mitochondrial turnover and dopaminergic neuronal loss in aged mice.

Noda S, Sato S, Fukuda T, Tada N, Uchiyama Y, Tanaka K, Hattori N