塗谷秀子 (Hideko Nuriya) - マイポータル - researchmap

基本情報

所属: 財団法人東京都医学研究機構東京都臨床医学総合研究所感染症プロジェクト研究部門研究員

学位: 理学士

J-GLOBAL ID: 200901090482751790
researchmap会員ID: 0000030698

外部リンク: http://www.rinshoken.or.jp/

研究キーワード

2

研究分野

1

ライフサイエンス / ウイルス学 /

経歴

6

1996年4月

東京都臨床医学総合研究所
1996年4月

Tokyo Metropolitan Organization for
1982年4月

東京都立広尾病院
1982年4月

Tokyo Metropolitan Hiro Hospil
Metropolitan Institute of Medical Science
Medical research, Tokyo

学歴

2

受賞

2

MISC

20

Detection of Hepatitis B and C Viruses in Almost All Hepatocytes by Modified PCR-Based In Situ Hybridization

Hideko Nuriya, Kazuaki Inoue, Takeshi Tanaka, Yukiko Hayashi, Tsunekazu Hishima, Nobuaki Funata, Kyosuke Kaji, Seishu Hayashi, Shuichi Kaneko, Michinori Kohara

JOURNAL OF CLINICAL MICROBIOLOGY 48(11) 3843-3851 2010年11月
Detection of Hepatitis B and C Viruses in Almost All Hepatocytes by Modified PCR-Based In Situ Hybridization

Hideko Nuriya, Kazuaki Inoue, Takeshi Tanaka, Yukiko Hayashi, Tsunekazu Hishima, Nobuaki Funata, Kyosuke Kaji, Seishu Hayashi, Shuichi Kaneko, Michinori Kohara

JOURNAL OF CLINICAL MICROBIOLOGY 48(11) 3843-3851 2010年11月
Hepatitis C virus impairs p53 via persistent over-expression of 3β-hydroxysterol ⊿24-reductase.

Nishimura T, Kohara M, Izumi K, Kasama Y, Hirata Y, Huang Y, Shuda M, Nuriya H, Tokunaga Y, Sato M …

J.Biol.Chem. 284(52) 36442-36452 2009年12月
Hepatitis C Virus Impairs p53 via Persistent Overexpression of 3 beta-Hydroxysterol Delta 24-Reductase

Tomohiro Nishimura, Michinori Kohara, Kosuke Izumi, Yuri Kasama, Yuichi Hirata, Ying Huang, Masahiro Shuda, Chise Mukaidani, Takashi Takano, Yuko Tokunaga …

JOURNAL OF BIOLOGICAL CHEMISTRY 284(52) 36442-36452 2009年12月
Hepatitis C virus NS5A protein interacts with and negatively regulates the non-receptor protein tyrosine kinase Syk

Sachiko Inubushi, Motoko Nagano-Fujii, Kikurni Kitayama, Motofumi Tanaka, Chunying An, Hiroshi Yokozaki, Hirohei Yamamura, Hideko Nuriya, Michinori Kohara, Kiyonao Sada …

JOURNAL OF GENERAL VIROLOGY 89(5) 1231-1242 2008年5月
Hepatitis C virus NS5A protein interacts with and negatively regulates the non-receptor protein tyrosine kinase Syk

Sachiko Inubushi, Motoko Nagano-Fujii, Kikurni Kitayama, Motofumi Tanaka, Chunying An, Hiroshi Yokozaki, Hirohei Yamamura, Hideko Nuriya, Michinori Kohara, Kiyonao Sada …

JOURNAL OF GENERAL VIROLOGY 89(5) 1231-1242 2008年5月
Virological significance of low-level hepatitis B virus infection in patients with hepatitis C liver disease.(Tanaka T., Inoue K., Hayashi Y., Abe A., Tsukiyama-Kohara K., Nuriya H.,Aoki Y., Kawaguchi R., Kubota K., Yoshiba M., Koike M.,Tanaka,S.and Ko・・・

J.Medical Virology 72: 223-229 2004年
Hepatitis C virus infection in human liver tissue engrafted in mice with an infectious molecular clone.( Maeda N., Watanabe M., Okamoto S, Kanai T., Hata J., Hozumi N., Katsume A., Nuriya H., Sandhu J., Ishii H., Kohara M.)

Liver International 259-267 2004年
Major Histocompatibility Complex Class-I Presentation Impaired in Transgenic Mice Expressing Hepatitis C Virus Structual Proteins During Dendritic Cell Maturation.( Hiasa Y., Takahashi H., Shimizu M., Nuriya H., Tsukiyama-Kohara K., Tanaka T., Horiike ・・・

J of Medical Virology 74: 253-261 2004年
Activation of the CKI-CDK-Rb-E2F Pathway in Full Genome Hepatitis C Virus-expressing Cells.(Tsukiyama-Kohara K., Tone S., Maruyama I., Inoue K., Asao K., Nuriya H., Ohmori H., Ohkawa J., Taira K., Hoshikawa Y.,Shibasaki F., Reth M.,Minatogawa Y. and Ko・・・

J of Bilological Chemistry 279.15:14531-114541 2004年
Virological significance of low-level hepatitis B virus infection in patients with hepatitis C liver disease.(Tanaka T., Inoue K., Hayashi Y., Abe A., Tsukiyama-Kohara K., Nuriya H.,Aoki Y., Kawaguchi R., Kubota K., Yoshiba M., Koike M.,Tanaka,S.and Ko・・・

J.Medical Virology 72: 223-229 2004年
Hepatitis C virus infection in human liver tissue engrafted in mice with an infectious molecular clone.( Maeda N., Watanabe M., Okamoto S, Kanai T., Hata J., Hozumi N., Katsume A., Nuriya H., Sandhu J., Ishii H., Kohara M.)

Liver International 259-267 2004年
Major Histocompatibility Complex Class-I Presentation Impaired in Transgenic Mice Expressing Hepatitis C Virus Structual Proteins During Dendritic Cell Maturation.( Hiasa Y., Takahashi H., Shimizu M., Nuriya H., Tsukiyama-Kohara K., Tanaka T., Horiike ・・・

J of Medical Virology 74: 253-261 2004年
Activation of the CKI-CDK-Rb-E2F Pathway in Full Genome Hepatitis C Virus-expressing Cells.(Tsukiyama-Kohara K., Tone S., Maruyama I., Inoue K., Asao K., Nuriya H., Ohmori H., Ohkawa J., Taira K., Hoshikawa Y.,Shibasaki F., Reth M.,Minatogawa Y. and Ko・・・

J of Bilological Chemistry 279.15:14531-114541 2004年
Impaired function of antigen-presenting dendritic cells in patients with chronic hepatitis B: Localization of HBV DNA and HBV RNA in blood DC by in situ hybridization.(Arima S.,Akebar S.,M Fazle, Michitaka K., Horiike N.,Nuriya H.,Kohara M.)

International J.MOL.MED. 11:169-174 2003年
PKR is increased and is functional in Hepatitis C virus-Related Hepatocellular Carcinoma.(Hiasa Y.,Kamegaya Y.,Nuriya H.,Onji M.,Schmidt E.V.,and Chung ,R.T.)

Amer.J.Gastroenterology. 98 (11) : 2528-2534 2003年
Impaired function of antigen-presenting dendritic cells in patients with chronic hepatitis B: Localization of HBV DNA and HBV RNA in blood DC by in situ hybridization.(Arima S.,Akebar S.,M Fazle, Michitaka K., Horiike N.,Nuriya H.,Kohara M.)

International J.MOL.MED. 11:169-174 2003年
PKR is increased and is functional in Hepatitis C virus-Related Hepatocellular Carcinoma.(Hiasa Y.,Kamegaya Y.,Nuriya H.,Onji M.,Schmidt E.V.,and Chung ,R.T.)

Amer.J.Gastroenterology. 98 (11) : 2528-2534 2003年
Direct evidence for IFN-G production by effector memory CD8+ T cells residing at an effector site of pathology in fixed drug eruption : A model for epidermal injury mediated by skin resident T cells.(Mizukawa Y.,Yamazaki Y.,Teraki Y.,Nuriya H.,Kohara M・・・

J.Amer. Patho. 161: 1337-1347 2002年
Direct evidence for IFN-G production by effector memory CD8+ T cells residing at an effector site of pathology in fixed drug eruption : A model for epidermal injury mediated by skin resident T cells.(Mizukawa Y.,Yamazaki Y.,Teraki Y.,Nuriya H.,Kohara M・・・

J.Amer. Patho. 161: 1337-1347 2002年

所属学協会

4

共同研究・競争的資金等の研究課題

2